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ChemicalBook >> CAS DataBase List >> Tubastatin A hydrochloride

Tubastatin A hydrochloride

Tubastatin A hydrochloride price.
  • $50 - $3994
  • Product name: Tubastatin A hydrochloride
  • CAS: 1310693-92-5
  • MF: C20H22ClN3O2
  • MW: 371.87
  • EINECS:
  • MDL Number:MFCD20488052
  • Synonyms:N-Hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide hydrochloride;Tubastatin A hydrochloride;TSA HCl;Tubastatin A Hydrochloride (Also See: T897000);Tubastatin A HCl salt;N-hydroxy-4-((2-methyl-1,2,3,4-tetrahydropyrido[4,3-b]indol-5-yl)methyl)benzamide hydrochloride;N-Hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide hydrochloride Tubastatin A HCl;Tubastatin A hydrochloride N-Hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide hydrochloride
27 prices
Selected condition：
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
Package
  • 20mg
  • 25mg
  • 10
  • 5MG
  • 10mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 500mg
  • 1g
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-3042-M010
  • Product descriptionTubastatinA.HCl ≥95%
  • Packaging10mg
  • Price$140
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN3042
  • Product descriptionTubastatinAHCl
  • Packaging10mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0002083
  • Product descriptionTUBASTATIN A HYDROCHLORIDE 95.00%
  • Packaging5MG
  • Price$504.9
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8547
  • Product descriptionTubastatinAHCl
  • Packaging100mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60282
  • Product descriptionTubastatinAHCl
  • Packaging20mg
  • Price$188
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS016601
  • Product descriptionTubastatin A hydrochloride ≥98%
  • Packaging250mg
  • Price$239
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2004
  • Product descriptionTubastatin A hydrochloride 99%
  • Packaging50mg
  • Price$357.5
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0498
  • Product descriptionTubastatin A hydrochloride 98.31%
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0498
  • Product descriptionTubastatin A hydrochloride 98.31%
  • Packaging10mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0498
  • Product descriptionTubastatin A hydrochloride 98.31%
  • Packaging50mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0498
  • Product descriptionTubastatin A hydrochloride 98.31%
  • Packaging100mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0498
  • Product descriptionTubastatin A hydrochloride 98.31%
  • Packaging200mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0498
  • Product descriptionTubastatin A hydrochloride 98.31%
  • Packaging500mg
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0498
  • Product descriptionTubastatin A hydrochloride 98.31%
  • Packaging1g
  • Price$1100
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003926
  • Product descriptionTubastatin A hydrochloride 98+%
  • Packaging10mg
  • Price$59
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003926
  • Product descriptionTubastatin A hydrochloride 98+%
  • Packaging50mg
  • Price$130
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences SYN-3042-M010 TubastatinA.HCl ≥95% 10mg $140 2021-12-16 Buy
AK Scientific SYN3042 TubastatinAHCl 10mg $150 2021-12-16 Buy
American Custom Chemicals Corporation INB0002083 TUBASTATIN A HYDROCHLORIDE 95.00% 5MG $504.9 2021-12-16 Buy
ApexBio Technology A8547 TubastatinAHCl 100mg $120 2021-12-16 Buy
Arctom CFN60282 TubastatinAHCl 20mg $188 2021-12-16 Buy
Arctom AS016601 Tubastatin A hydrochloride ≥98% 250mg $239 2021-12-16 Buy
Axon Medchem Axon2004 Tubastatin A hydrochloride 99% 50mg $357.5 2021-12-16 Buy
ChemScene CS-0498 Tubastatin A hydrochloride 98.31% 5mg $50 2021-12-16 Buy
ChemScene CS-0498 Tubastatin A hydrochloride 98.31% 10mg $60 2021-12-16 Buy
ChemScene CS-0498 Tubastatin A hydrochloride 98.31% 50mg $90 2021-12-16 Buy
ChemScene CS-0498 Tubastatin A hydrochloride 98.31% 100mg $150 2021-12-16 Buy
ChemScene CS-0498 Tubastatin A hydrochloride 98.31% 200mg $250 2021-12-16 Buy
ChemScene CS-0498 Tubastatin A hydrochloride 98.31% 500mg $600 2021-12-16 Buy
ChemScene CS-0498 Tubastatin A hydrochloride 98.31% 1g $1100 2021-12-16 Buy
Crysdot CD31003926 Tubastatin A hydrochloride 98+% 10mg $59 2021-12-16 Buy
Crysdot CD31003926 Tubastatin A hydrochloride 98+% 50mg $130 2021-12-16 Buy

Properties

Melting point :>221°C (subl.)
storage temp. :-20°C
solubility :Soluble in DMSO or Water.
form :powder
color :white to tan
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

Tubastatin A (1310693-92-5) is a potent and highly selective inhibitor of HDAC6 (IC50?= 15 nM, >1000-fold selectivity against other HDAC isoforms, approx. 60-fold versus HDAC8).1?It displayed anti-inflammatory and anti-rheumatic effects in Freund’s competitive adjuvant induced animal model of inflammation.2?Tubastatin A inhibited TNF-α (IC50?= 272 nM) and IL-6 (IC50 = 712 nM) in LPS stimulated human THP-1 macrophages.2?Tubastatin A has also been shown to have therapeutic potential for treatment of Alzheimer’s disease via altered amyloid-β load and reduced tau hyperphosphorylation.3-5

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