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ChemicalBook >> CAS DataBase List >> 1,5-ISOQUINOLINEDIOL

1,5-ISOQUINOLINEDIOL

1,5-ISOQUINOLINEDIOL price.
  • $30 - $1442
  • Product name: 1,5-ISOQUINOLINEDIOL
  • CAS: 5154-02-9
  • MF: C9H7NO2
  • MW: 161.16
  • EINECS:637-104-6
  • MDL Number:MFCD00006900
  • Synonyms:1,5-ISOQUINOLINEDIOL;1,5-DIHYDROXYISOQUINOLINE;5-HYDROXYISOCARBOSTYRIL;5-HYDROXY-1(2H)-ISOQUINOLINE;5-HYDROXY-1(2H)-ISOQUINOLINONE;1,5-ISOQUINOLINEDIOL(1,5-DIHYDROXYISOQUI NO-LINE);1,5-Dihydroxyisoquinoline, 5-Hydroxy-1(2H)-isoquinolinone, DiQ;5-Hydroxyisoquinoline-1(2H)-one
20 prices
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Brand
  • Adipogen Life Sciences
  • AK Scientific
  • Alichem
  • Axon Medchem
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • Frontier Specialty Chemicals
  • Matrix Scientific
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 2.500g
  • 2.5g
  • 5g
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-0024-M005
  • Product description1,5-Isoquinolinediol ≥98%(NMR)
  • Packaging5mg
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number7630AJ
  • Product description1,5-Isoquinolinediol
  • Packaging2.5g
  • Price$1336
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number5154029
  • Product description5-Hydroxyisoquinoline-1(2H)-one
  • Packaging1g
  • Price$793.8
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2537
  • Product description1,5-Isoquinolinediol-NSC65585 100%
  • Packaging10mg
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2537
  • Product description1,5-Isoquinolinediol-NSC65585 100%
  • Packaging50mg
  • Price$104.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number14438
  • Product description1,5-Isoquinolinediol ≥98%
  • Packaging5mg
  • Price$36
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14438
  • Product description1,5-Isoquinolinediol ≥98%
  • Packaging25mg
  • Price$78
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14438
  • Product description1,5-Isoquinolinediol ≥98%
  • Packaging100mg
  • Price$207
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-W016138
  • Product description1,5-Isoquinolinediol 99.33%
  • Packaging25mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-W016138
  • Product description1,5-Isoquinolinediol 99.33%
  • Packaging50mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-W016138
  • Product description1,5-Isoquinolinediol 99.33%
  • Packaging100mg
  • Price$500
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD41000904
  • Product description5-Hydroxyisoquinoline-1(2H)-one 95+%
  • Packaging1g
  • Price$749
  • Updated2021-12-16
  • Buy
  • ManufacturerFrontier Specialty Chemicals
  • Product numberJK438800
  • Product description1,5-Isoquinolinediol 97%
  • Packaging250mg
  • Price$355
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number136882
  • Product descriptionIsoquinoline-1,5-diol 95%+
  • Packaging2.500g
  • Price$953
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number136882
  • Product descriptionIsoquinoline-1,5-diol 95%+
  • Packaging5g
  • Price$1442
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberI138
  • Product description1,5-Isoquinolinediol ≥98% (HPLC), powder
  • Packaging5MG
  • Price$59.9
  • Updated2022-05-15
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CR1-0024-M005 1,5-Isoquinolinediol ≥98%(NMR) 5mg $30 2021-12-16 Buy
AK Scientific 7630AJ 1,5-Isoquinolinediol 2.5g $1336 2021-12-16 Buy
Alichem 5154029 5-Hydroxyisoquinoline-1(2H)-one 1g $793.8 2021-12-16 Buy
Axon Medchem Axon2537 1,5-Isoquinolinediol-NSC65585 100% 10mg $55 2021-12-16 Buy
Axon Medchem Axon2537 1,5-Isoquinolinediol-NSC65585 100% 50mg $104.5 2021-12-16 Buy
Cayman Chemical 14438 1,5-Isoquinolinediol ≥98% 5mg $36 2024-03-01 Buy
Cayman Chemical 14438 1,5-Isoquinolinediol ≥98% 25mg $78 2024-03-01 Buy
Cayman Chemical 14438 1,5-Isoquinolinediol ≥98% 100mg $207 2024-03-01 Buy
ChemScene CS-W016138 1,5-Isoquinolinediol 99.33% 25mg $200 2021-12-16 Buy
ChemScene CS-W016138 1,5-Isoquinolinediol 99.33% 50mg $300 2021-12-16 Buy
ChemScene CS-W016138 1,5-Isoquinolinediol 99.33% 100mg $500 2021-12-16 Buy
Crysdot CD41000904 5-Hydroxyisoquinoline-1(2H)-one 95+% 1g $749 2021-12-16 Buy
Frontier Specialty Chemicals JK438800 1,5-Isoquinolinediol 97% 250mg $355 2021-12-16 Buy
Matrix Scientific 136882 Isoquinoline-1,5-diol 95%+ 2.500g $953 2021-12-16 Buy
Matrix Scientific 136882 Isoquinoline-1,5-diol 95%+ 5g $1442 2021-12-16 Buy
Sigma-Aldrich I138 1,5-Isoquinolinediol ≥98% (HPLC), powder 5MG $59.9 2022-05-15 Buy

Properties

Melting point :270-275 °C
Boiling point :287.44°C (rough estimate)
Density :1.2480 (rough estimate)
refractive index :1.5050 (estimate)
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :DMSO: >36 mg/mL
form :solid
pka :8.52±0.20(Predicted)
color :off-white
CAS DataBase Reference :5154-02-9(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P233 Keep container tightly closed.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304 IF INHALED:
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P340 Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362 Take off contaminated clothing and wash before reuse.
P403 Store in a well-ventilated place.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis. 1,5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1; IC50 = 0.39 μM). It has been used to study the role of PARP1 in both DNA repair and oxidant stress-induced cell death. This compound can be used with cells in culture and in animals.

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