100% purity available from supplier Axon Medchem, prime source of life science reagents for your research" />
JavaScript seems to be disabled in your browser. You must have JavaScript enabled in your browser to utilize the functionality of this website.
There are no items in your shopping cart
Featured Products
Axon 2537
CAS [5154-02-9]
MF C9H7NO2MW 161.16
PARP1-specific inhibitor (IC50 value 0.39 - 1.00 μM) and neuroprotective agent, that leads to an increase up to 8-fold in the absolute frequency of gene targeting in the correction of the mutation at the stable integrated HSV tk gene in mouse Ltk cells. Treatment of 1,5-Isoquinolinediol significantly blocked mitochondrial membrane potential loss and AIF (apoptosis inducing factor) and cytochrome c release from the mitochondria. 1,5-Isoquinolinediol did not suppress pristimerin-induced JNK activation.
KEYWORDS: 1,5-Isoquinolinediol | supplier | PARP inhibitor |NSC65585 |NSC65585 | CAS [5154-02-9] |DNA-RNA | PARP1 | Inhibitor | DHIQ | DIQ | poly |ADP-ribose | SSB | single strand breaks | Ltk cells | mitochondrial membrane potential |AIF| apoptosis inducing factor | neuroprotetcive | JNK
5-hydroxyisoquinolin-1(2H)-one
[5154-02-9]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
Download the Axon Ligands™ catalogue 2021 Spring Edition
* Required Fields