100% purity available from supplier Axon Medchem, prime source of life science reagents for your research" />

成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

1,5-Isoquinolinediol - NSC 65585

Based on 240 reference(s) in Google Scholar 9 10 240

Axon 2537

CAS [5154-02-9]

MF C9H7NO2
MW 161.16

  • Purity: 100%
  • Soluble in 0.1N NaOH(aq) and DMSO

1,5-Isoquinolinediol

Description

PARP1-specific inhibitor (IC50 value 0.39 - 1.00 μM) and neuroprotective agent, that leads to an increase up to 8-fold in the absolute frequency of gene targeting in the correction of the mutation at the stable integrated HSV tk gene in mouse Ltk cells. Treatment of 1,5-Isoquinolinediol significantly blocked mitochondrial membrane potential loss and AIF (apoptosis inducing factor) and cytochrome c release from the mitochondria. 1,5-Isoquinolinediol did not suppress pristimerin-induced JNK activation.

KEYWORDS: 1,5-Isoquinolinediol | supplier | PARP inhibitor |NSC65585 |NSC65585 | CAS [5154-02-9] |DNA-RNA | PARP1 | Inhibitor | DHIQ | DIQ | poly |ADP-ribose | SSB | single strand breaks | Ltk cells | mitochondrial membrane potential |AIF| apoptosis inducing factor | neuroprotetcive | JNK

Order
Size Unit Price Stock
10 mg $55.00 In Stock
50 mg $104.50 In Stock
Need more? Bulk Inquiry

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

Please wait...