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AZD1152

AZD1152 ??? ???
?? ??:
722543-31-9
???:
AZD1152
???(??):
AZD1152;CS-1053;Barasertib (AZD1152);Barasertib, 10 mM in DMSO;BARASERTIB; AZD-1152; AZD 1152;5-[[7-[3-[Ethyl[2-(phosphonooxy)ethyl]amino]propoxy]-4-quinazolinyl]amino]-N-(3-fluorophenyl)-1H-pyrazole-3-acetamide;1H-Pyrazole-3-acetamide, 5-[[7-[3-[ethyl[2-(phosphonooxy)ethyl]amino]propoxy]-4-quinazolinyl]amino]-N-(3-fluorophenyl)-;2-(Ethyl(3-((4-((3-(2-((3-fluorophenyl)amino)-2-oxoethyl)-1H-pyrazol-5-yl)amino)quinazolin-7-yl)oxy)propyl)amino)ethyl dihydrogen phosphate;2-[[3-({4-[(5-{2-[(3-fluorophenyl)amino]-2-oxoethyl}-1H-pyrazol-3-yl)amino]quinazolin-7-yl}oxy)propyl](ethyl)amino]ethyl dihydrogen phosphate
CBNumber:
CB72476033
???:
C26H31FN7O6P
??? ??:
587.54
MOL ??:
722543-31-9.mol

AZD1152 ??

??
1.463
?? ??
under inert gas (nitrogen or Argon) at 2–8 °C
???
insoluble in H2O; insoluble in EtOH; ≥5.88 mg/mL in DMSO
??? ??
??
??? ??
??? ??
?? ?? (pKa)
1.75±0.10(Predicted)
??
Off-white to light yellow

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AZD1152 C??? ??, ??, ??

AZD1152 ?? ?? ? ???

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AZD1152 ?? ??

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