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ChemicalBook >> CAS DataBase List >>AZD1152

AZD1152

CAS No.
722543-31-9
Chemical Name:
AZD1152
Synonyms
AZD1152;CS-1053;Barasertib (AZD1152);Barasertib, 10 mM in DMSO;BARASERTIB; AZD-1152; AZD 1152;5-[[7-[3-[Ethyl[2-(phosphonooxy)ethyl]amino]propoxy]-4-quinazolinyl]amino]-N-(3-fluorophenyl)-1H-pyrazole-3-acetamide;1H-Pyrazole-3-acetamide, 5-[[7-[3-[ethyl[2-(phosphonooxy)ethyl]amino]propoxy]-4-quinazolinyl]amino]-N-(3-fluorophenyl)-;2-(Ethyl(3-((4-((3-(2-((3-fluorophenyl)amino)-2-oxoethyl)-1H-pyrazol-5-yl)amino)quinazolin-7-yl)oxy)propyl)amino)ethyl dihydrogen phosphate;2-[[3-({4-[(5-{2-[(3-fluorophenyl)amino]-2-oxoethyl}-1H-pyrazol-3-yl)amino]quinazolin-7-yl}oxy)propyl](ethyl)amino]ethyl dihydrogen phosphate
CBNumber:
CB72476033
Molecular Formula:
C26H31FN7O6P
Molecular Weight:
587.54
MDL Number:
MFCD15146330
MOL File:
722543-31-9.mol
Last updated:2024-11-19 20:33:22

AZD1152 Properties

Density 1.463
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility insoluble in H2O; insoluble in EtOH; ≥5.88 mg/mL in DMSO
form solid
pka 1.75±0.10(Predicted)
color Off-white to light yellow
FDA UNII 16XC2U7W8N

AZD1152 price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 13647 AZD 1152 ≥95% 722543-31-9 1mg $65 2021-12-16 Buy
Cayman Chemical 13647 AZD 1152 ≥95% 722543-31-9 5mg $293 2021-12-16 Buy
Cayman Chemical 13647 AZD 1152 ≥95% 722543-31-9 10mg $488 2021-12-16 Buy
Cayman Chemical 13647 AZD 1152 ≥95% 722543-31-9 25mg $975 2021-12-16 Buy
TRC B129135 Barasertib 722543-31-9 5mg $205 2021-12-16 Buy
Product number Packaging Price Buy
13647 1mg $65 Buy
13647 5mg $293 Buy
13647 10mg $488 Buy
13647 25mg $975 Buy
B129135 5mg $205 Buy

AZD1152 Chemical Properties,Uses,Production

Uses

Barasertib. is a selective inhibitor of Aurora B kinase, which inhibits human tumor xenograft growth by inducing apoptosis.

Definition

ChEBI: AZT-1152 is a dihydrogen phosphate prodrug of a pyrazoloquinazoline aurora kinase inhibitor AZD1152-hydroxyquinazoline pyrazol anilide(HQPA) and is converted rapidly to the active AZD1152-HQPA in plasma. It has a role as a prodrug, an antineoplastic agent and an Aurora kinase inhibitor. It is a member of quinazolines, a monoalkyl phosphate, an anilide, a member of monofluorobenzenes, a member of pyrazoles, a secondary amino compound, a secondary carboxamide and a tertiary amino compound. It is functionally related to an AZD-1152.

AZD1152 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 102)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29730 60
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49732 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32159 58
ANHUI WITOP BIOTECH CO., LTD 		+8615255079626 eric@witopchemical.com China 23541 58
Hefei Hirisun Pharmatech Co., Ltd 		+8615056975894 shawn@hirisunpharm.com CHINA 9911 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38630 58
Hu Bei Jiutian Bio-medical Technology CO.,Ltd 		027-88013699 17354350817 Ryan@jiutian-bio.com China 6001 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		13417589054 trendseenbio@gmail.com China 11681 58
Wuhan Han Sheng New Material Technology Co.，Ltd 		+8617798174412 admin01@hsnm.com.cn China 2097 58

View Lastest Price from AZD1152 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Barasertib pictures 2024-11-19 Barasertib
722543-31-9
 US $42.00-118.00 / mg 99.63% 10g TargetMol Chemicals Inc.
Barasertib pictures 2024-11-19 Barasertib
722543-31-9
 US $42.00-118.00 / mg 99.63% 10g TargetMol Chemicals Inc.
  • Barasertib pictures
  • Barasertib
    722543-31-9
  • US $42.00-118.00 / mg
  • 99.63%
  • TargetMol Chemicals Inc.
  • Barasertib pictures
  • Barasertib
    722543-31-9
  • US $42.00-118.00 / mg
  • 99.63%
  • TargetMol Chemicals Inc.

AZD1152 Spectrum

1H-Pyrazole-3-acetamide, 5-[[7-[3-[ethyl[2-(phosphonooxy)ethyl]amino]propoxy]-4-quinazolinyl]amino]-N-(3-fluorophenyl)- AZD1152 5-[[7-[3-[Ethyl[2-(phosphonooxy)ethyl]amino]propoxy]-4-quinazolinyl]amino]-N-(3-fluorophenyl)-1H-pyrazole-3-acetamide BARASERTIB; AZD-1152; AZD 1152 Barasertib (AZD1152) CS-1053 2-[[3-({4-[(5-{2-[(3-fluorophenyl)amino]-2-oxoethyl}-1H-pyrazol-3-yl)amino]quinazolin-7-yl}oxy)propyl](ethyl)amino]ethyl dihydrogen phosphate 2-(Ethyl(3-((4-((3-(2-((3-fluorophenyl)amino)-2-oxoethyl)-1H-pyrazol-5-yl)amino)quinazolin-7-yl)oxy)propyl)amino)ethyl dihydrogen phosphate Barasertib, 10 mM in DMSO 722543-31-9