ChemicalBook >?? ???? >API>???>? ?? ??? ??>(6R-trans)-7-[2-(2-??????-4-?)?????]-3-[[[1-[2-(??????)??]-1H-????-5-?]??]??]-8-??-5-??-1-????????[4.2.0]??-2-?-2-????? ??????????
(6R-trans)-7-[2-(2-??????-4-?)?????]-3-[[[1-[2-(??????)??]-1H-????-5-?]??]??]-8-??-5-??-1-????????[4.2.0]??-2-?-2-????? ??????????
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![(6R-trans)-7-[2-(2-??????-4-?)?????]-3-[[[1-[2-(??????)??]-1H-????-5-?]??]??]-8-??-5-??-1-????????[4.2.0]??-2-?-2-????? ??????????](CAS/GIF/66309-69-1.gif)
(6R-trans)-7-[2-(2-??????-4-?)?????]-3-[[[1-[2-(??????)??]-1H-????-5-?]??]??]-8-??-5-??-1-????????[4.2.0]??-2-?-2-????? ?????????? ??
- ???
- >93°C (dec.)
- ?? ?
- 94℃
- RTECS ??
- XI0367000
- ???
- >110°(230°F)
- ?? ??
- Inert atmosphere,2-8°C
- ???
- H2O: ≥22M
- ??? ??
- ??
- ??
- ???? ?????
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- InChIKey
- BWRRTAXZCKVRON-DGPOFWGLSA-N
- CAS ??????
- 66309-69-1(CAS DataBase Reference)
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- ?? ? ???? ?? (GHS)
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(6R-trans)-7-[2-(2-??????-4-?)?????]-3-[[[1-[2-(??????)??]-1H-????-5-?]??]??]-8-??-5-??-1-????????[4.2.0]??-2-?-2-????? ?????????? C??? ??, ??, ??
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Cefotiam was synthesized by Takeda Chemicals Industries in 1977 as the first cephem derivative to introduce the aminothiazol group in the 7 side chain and the alkylated tetrazole group at the 3 side chain . This drug shows greater antibacterial activity against gram-negative bacteria than the earlier cephalosporins, including Enterobacter, Citrobacter, and indole-positive Proteus, and it retains the same activity as they have against gram-positive organisms. Its excellent activity against Klebsiella and Escherichia coli is based on its ability to penetrate the cell. This is 3- to 70-fold greater than that of cephalothin or cefazolin.??
ChEBI: Cefotiam dihydrochloride is the dihydrochloride salt of cefotiam. It has a role as an antibacterial drug. It contains a cefotiam.???
Ceradon (Takeda).(6R-trans)-7-[2-(2-??????-4-?)?????]-3-[[[1-[2-(??????)??]-1H-????-5-?]??]??]-8-??-5-??-1-????????[4.2.0]??-2-?-2-????? ?????????? ?? ?? ? ???
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(6R-trans)-7-[2-(2-??????-4-?)?????]-3-[[[1-[2-(??????)??]-1H-????-5-?]??]??]-8-??-5-??-1-????????[4.2.0]??-2-?-2-????? ?????????? ?? ??
???( 286)?? ??
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(6R-trans)-7-[2-(2-??????-4-?)?????]-3-[[[1-[2-(??????)??]-1H-????-5-?]??]??]-8-??-5-??-1-????????[4.2.0]??-2-?-2-????? ?????????? ?? ??:
???? ??? ??, ??? ?? (6R-trans)-7-[2-(2-??????-4-?)?????]-3-[[[1-[2-(??????)??]-1H-????-5-?]??]??]-8-??-5-??-1-????????[4.2.0]??-2-?-2-????? ??????????
Ceftiofur hydrochloride
Bromhexine hydrochloride
Cefcapene pivoxil hydrochloride
Metoclopramide hydrochloride
Cefazedone sodium salt
Cefonicid sodium
Cemandil sodium salt
Ceftezole sodium
Oxytetracycline hydrochloride
Cefozopran hydrochloride
Cefetamet pivoxil hydrochloride
Cefmenoxime hydrochloride
Nitrocefin
Ceftazidime
1-[2-(Dimethylamino)ethyl]-1H-tetrazole-5-thiol