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2-Amino-4-methoxypyridine

2-Amino-4-methoxypyridine ??? ???
?? ??:
10201-73-7
???:
2-Amino-4-methoxypyridine
???(??):
4-METHOXYPYRIDIN-2-AMINE;4-METHOXY-PYRIDIN-2-YLAMINE;KML-35;CML-032;4-Methoxypyridin-2-amin;2-PyridinaMine,4-Methoxy;4-Methoxy-2-pyridinamine;4-Methoxy-2-aMinopyridine;2-AMINO-4-METHOXYPYRIDINE;2-AMINO-4-METHOXYLPYRIDINE
CBNumber:
CB2379186
???:
C6H8N2O
??? ??:
124.14
MOL ??:
10201-73-7.mol

2-Amino-4-methoxypyridine ??

???
120-121°C
?? ?
258.6±20.0 °C(Predicted)
??
1.139±0.06 g/cm3(Predicted)
?? ??
Keep in dark place,Inert atmosphere,Room temperature
???
DMSO????? ???
?? ?? (pKa)
7.79±0.11(Predicted)
??? ??
??
??? ??
??? ??
??
?? ??
???
????????, ???? ?????. ?? ?? ?????.
??
Air Sensitive
?? ??(λmax)
280nm(CHCl3)(lit.)
InChI
InChI=1S/C6H8N2O/c1-9-5-2-3-8-6(7)4-5/h2-4H,1H3,(H2,7,8)
InChIKey
QPHBCOSULYSASF-UHFFFAOYSA-N
SMILES
C1(N)=NC=CC(OC)=C1
CAS ??????
10201-73-7(CAS DataBase Reference)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi,Xn
?? ???? ?? 22-36/37/38
????? 36/37/39
WGK ?? 3
?? ?? IRRITANT
?? ?? 6.1
HS ?? 2933399990
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P270 ? ??? ??? ??? ???, ???? ???? ???.
P301+P312 ??? ???? ??? ????(??)? ??? ????.
P302+P352 ??? ??? ??? ?? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
NFPA 704
0
2 0

2-Amino-4-methoxypyridine C??? ??, ??, ??

??? ??

Pale Yellow Solid

??

2-Amino-4-methoxypyridine is a highly selective inducible nitric oxide synthase inhibitors.

Synthesis Reference(s)

The Journal of Organic Chemistry, 72, p. 4554, 2007 DOI: 10.1021/jo070189y

2-Amino-4-methoxypyridine ?? ?? ? ???

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?? ??


2-Amino-4-methoxypyridine ?? ??

???( 313)?? ??
??? ?? ??? ?? ?? ? ??
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2-Amino-4-methoxypyridine ?? ??:

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