7-??????-3-??-4H-1-????-4-?
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7-??????-3-??-4H-1-????-4-? ??
- ???
- 116-120 °C(lit.)
- ?? ?
- 363.04°C (rough estimate)
- ??
- 1.2170 (rough estimate)
- ???
- 1.4700 (estimate)
- ?? ??
- Sealed in dry,Room Temperature
- ???
- DMF:20.0(Max Conc. mg/mL);71.35(Max Conc. mM)
DMF:PBS (pH 7.2) (1:4):0.2(Max Conc. mg/mL);0.71(Max Conc. mM)
DMSO:33.11(Max Conc. mg/mL);118.11(Max Conc. mM)
Ethanol:1.5(Max Conc. mg/mL);5.35(Max Conc. mM)
- ??? ??
- powder to crystal
- ??
- ???? ?? ??
- Merck
- 14,5074
- InChI
- InChI=1S/C18H16O3/c1-12(2)21-14-8-9-15-17(10-14)20-11-16(18(15)19)13-6-4-3-5-7-13/h3-12H,1-2H3
- InChIKey
- SFBODOKJTYAUCM-UHFFFAOYSA-N
- SMILES
- C1OC2=CC(OC(C)C)=CC=C2C(=O)C=1C1=CC=CC=C1
- LogP
- 4.245 (est)
- CAS ??????
- 35212-22-7(CAS DataBase Reference)
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- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? | Xi | ||
|---|---|---|---|
| ?? ???? ?? | 36/37/38 | ||
| ????? | 24/25-36/37/39-27-26 | ||
| WGK ?? | 2 | ||
| RTECS ?? | DJ3100500 | ||
| HS ?? | 29329990 |
| ????(GHS): |
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| ?? ?: | Warning | ||||||||||||||||||||||||||||
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7-??????-3-??-4H-1-????-4-? C??? ??, ??, ??
??
Ipriflavone, a derivative of isoflavone, is a calcium metabolism regulator useful in the treatment of primary and secondary osteoporosis, as well as disorders of osteogenesis. It appears to be without significant side-effects.??? ??
white powder??
7-Isopropoxy-3-phenyl-4H-1-benzopyran-4-one (Ipriflavone) has been used as a model drug in a study to functionalize the mesoporous bioactive glasses (MBG). Study suggested that since ipriflavone is a hydrophobic anti-osteoporotic drug, it easily attaches to the surface of MBG and results in long-term drug delivery.??
ChEBI: Ipriflavone is a member of the class of isoflavones that is isoflavone in which the hydrogen at position 7 is replaced by an isopropoxy group. A synthetic isoflavone, it was formerly used for the treatment of osteoporosis, although a randomised controlled study failed to show any benefit. It is still used to prevent osteoporosis in post-menopausal women. It has a role as a bone density conservation agent. It is a member of isoflavones and an aromatic ether.benefits
Ipriflavone is used clinically to treat osteoporosis. Bodybuilders also use ipriflavone, but enough experimental data supports this purpose. It has been shown to have anti-inflammatory and antioxidant activity. It helps to reduce bone loss, increase bone density, and reduce the risk of developing osteoporosis. It has also been found to help reduce neuroinflammation . In addition, it has been found to help reduce the risk of certain types of cancer, improve cognitive function and reduce the risk of depression.?? ??
7-Isopropoxy-3-phenyl-4H-1-benzopyran-4-one (Ipriflavone), a synthetic flavonoid, is reported to stimulate the activity of osteoblasts. It is reported to promote the deposition of calcium and the formation of mineralized nodules by newborn rat calvarial osteoblast-like (ROB) cells as well as the activity of alkaline phosphatase. Ipriflavone, an isoflavone derivative, is a new drug used to decrease bone loss in osteoporosis.???
Ipriflavone should be taken under medical supervision only. It can produce side effects such as stomach pain, diarrhoea, dizziness, etc. It may have a sudden increase in the WBC count if administered for six months or more. When the treatment with Ipriflavone is on, it is suggested that the WBC count should be monitored.7-??????-3-??-4H-1-????-4-? ?? ?? ? ???
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PHENYLZINC BROMIDE
2',4'-?????-2-???????
????? ??
7-Hydroxyisoflavone
?????????
?? ??
7-??????-3-??-4H-1-????-4-? ?? ??
???( 389)?? ??
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7-??????-3-??-4H-1-????-4-? ?? ??:
??? ????? ?????? ???(IV) ??????? 7-??????-3-??-4H-1-????-4-?
PHENYL VALERATE
1-(2,6-Dimethylphenoxy)-2-propanamine
Eplerenone
EPROSARTAN
Erythromycin Estolate
Eprinomectin
Etodolac
Ipriflavone Impurity D
7-Hydroxyisoflavone
ISOFLAVONES
5-HYDROXYDEQUELIN
ISO-OSAJIN
2-[(4-OXO-3-PHENYL-4H-CHROMEN-7-YL)OXY]PROPANOIC ACID