Z-PHE-DL-ALA-FLUOROMETHYLKETONE
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- CAS-Nr.
- 197855-65-5
- Englisch Name:
- Z-PHE-DL-ALA-FLUOROMETHYLKETONE
- Synonyma:
- CS-1504;Z-Phe-DL-Ala-FMK;Z-PHE-DL-ALA-FLUOROMETHYLKETONE;Nalpha-[(Benzyloxy)Carbonyl]-N-(4-Fluoro-3-Oxo-2-Butanyl)Phenylalaninamide;Benzyl ((2S)-1-((4-fluoro-3-oxobutan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate;Nalpha-[(Benzyloxy)Carbonyl]-N-(4-Fluoro-3-Oxo-2-Butanyl)Phenylalaninamide z-fa-fmk;Carbamic acid,N-[(1S)-2-[(3-fluoro-1-methyl-2-oxopropyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-,phenylmethyl ester;SARS coronavirus,SARS-CoV,RRMs,DNA fragmentation,DEVDase,Caspase,Cathepsin,Inhibitor,externalization of phosphatidylserine,Apoptosis,inhibit,Z FA FMK,reovirus replication,ZFAFMK
- CBNumber:
- CB9710726
- Summenformel:
- C21H23FN2O4
- Molgewicht:
- 386.42
- MOL-Datei:
- 197855-65-5.mol
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Z-PHE-DL-ALA-FLUOROMETHYLKETONE Eigenschaften
- Siedepunkt:
- 630.5±55.0 °C(Predicted)
- Dichte
- 1?+-.0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,2-8°C
- L?slichkeit
- DMF: 5 mg/ml; DMSO: 5 mg/ml
- pka
- 11.07±0.46(Predicted)
- Aggregatzustand
- White solid
- Farbe
- White to off-white
Sicherheit
Z-PHE-DL-ALA-FLUOROMETHYLKETONE Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Z-
FA-
FMK is an irreversible inhibitor of cysteine proteases, including cathepsins B, L, and S, cruzain, and papain. It also inhibits effector caspases-
2, -
3, -
6, and -
7 (IC
50 = 6-
32 μM) without affecting the initiator caspases-
8 and -
10. Z-
FA-
FMK also modulates infection by certain bacteria, parasites, and viruses. It can be used both in cells and
in vivo.
Verwenden
Z-FA-FMK is an irreversible cysteine protease inhibitor. It also inhibits papain and cruzain.
Z-PHE-DL-ALA-FLUOROMETHYLKETONE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Z-PHE-DL-ALA-FLUOROMETHYLKETONE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 88)Lieferanten
197855-65-5()Verwandte Suche:
- Z-PHE-DL-ALA-FLUOROMETHYLKETONE
- Carbamic acid,N-[(1S)-2-[(3-fluoro-1-methyl-2-oxopropyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-,phenylmethyl ester
- Nalpha-[(Benzyloxy)Carbonyl]-N-(4-Fluoro-3-Oxo-2-Butanyl)Phenylalaninamide z-fa-fmk
- Nalpha-[(Benzyloxy)Carbonyl]-N-(4-Fluoro-3-Oxo-2-Butanyl)Phenylalaninamide
- CS-1504
- Z-Phe-DL-Ala-FMK
- Benzyl ((2S)-1-((4-fluoro-3-oxobutan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate
- SARS coronavirus,SARS-CoV,RRMs,DNA fragmentation,DEVDase,Caspase,Cathepsin,Inhibitor,externalization of phosphatidylserine,Apoptosis,inhibit,Z FA FMK,reovirus replication,ZFAFMK
- 197855-65-5
- C21H23FN2O4
- Inhibitors
- API