WITHAFERIN A
|
|
|
- CAS-Nr.
- 5119-48-2
- Englisch Name:
- WITHAFERIN A
- Synonyma:
- NSC 273757;nsc-101088;upeferinA.;Withaferine;WITHAFERIN A;withaferinea;Withaferin A-RM;Withaferin A Standard;Withaferin A 5119-48-2;delta-lactone,(20s,22r)-oxo
- CBNumber:
- CB9454365
- Summenformel:
- C28H38O6
- Molgewicht:
- 470.6
- MOL-Datei:
- 5119-48-2.mol
|
WITHAFERIN A Eigenschaften
- Schmelzpunkt:
- 252-253℃
- alpha
- D28 +125° (c = 1.30 in CHCl3)
- Siedepunkt:
- 680.7±55.0 °C(Predicted)
- Dichte
- 1.28
- Flammpunkt:
- 226℃
- storage temp.
- Desiccate at -20°C
- L?slichkeit
- Soluble in DMSO (up to 20 mg/ml)
- pka
- 13.49±0.70(Predicted)
- Aggregatzustand
- White solid
- Farbe
- White
- Stabilit?t:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
- InChIKey
- DBRXOUCRJQVYJQ-CKNDUULBSA-N
WITHAFERIN A Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
Solid
Definition
ChEBI: A withanolide that is 5,6:22,26-diepoxyergosta-2,24-diene-1,26-dione substituted by hydroxy groups at positions 4 and 27 (the 4beta,5beta,6beta,22R stereoisomer). Isolated from Phys
lis longifolia, it exhibits cytotoxic activity.
Biologische Aktivit?t
Steroid lactone that displays anti-inflammatory, antitumor and antiangiogenic activity. Inhibits endothelial cells (HUVEC) spouting in vitro (IC 50 = 12 nM) and in vivo . Prevents NF- κ B activation by inhibiting activation of IKK β . Also inhibits chymotrypsin-like activity of the 20S proteasome.
WITHAFERIN A Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
WITHAFERIN A Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 138)Lieferanten
5119-48-2()Verwandte Suche:
- WITHAFERIN A
- 5,6-beta-epoxy-4-beta,22,27-trihydroxy-1-5-beta-ergosta-24-dien-26-oicacid
- delta-lactone,(20s,22r)-oxo
- nsc-101088
- (4β,5β,6β,22R)-5,6-Epoxy-4,22,27-trihydroxy-1-oxoergosta-2,24-dien-26-oicacidδ-lactone
- NSC 273757
- Withaferine
- (20S,22R)-5,6β-Epoxy-4β,22,27-trihydroxy-1-oxo-5β-ergosta-
2,24-dien-26-oic Acid δ-Lactone
- Withaferin A NSC 273757 NSC 101088
- 5,6-Epoxy-4,27-dihydroxy-1-oxowitha-2,24-dienolide
- withaferinea
- Withaferin A from leaves of Withania somnifera
- Ergosta-2,24-dien-26-oicacid, 5,6-epoxy-4,22,27-trihydroxy-1-oxo-, d-lactone, (4b,5b,6b,22R)-
- Withaferin A, Withania somnifera - CAS 5119-48-2 - Calbiochem
- Withaferin A 5119-48-2
- Withaferin A Standard
- Ergosta-2,24-dien-26-oic acid, 5,6-epoxy-4,22,27-trihydroxy-1-oxo-, δ-lactone, (4β,5β,6β,22R)-
- AshwagandhaQ: What is
Ashwagandha Q: What is the CAS Number of
Ashwagandha Q: What is the storage condition of
Ashwagandha
- (4beta,5beta,6beta,22R)-4,27-dihydroxy-5,6:22,26-diepoxyergosta-2,24-diene-1,26-dione
- upeferinA.
- (4S,4aR,5aR,6aS,6bS,9R,9aS,11aS,11bR)-4-Hydroxy-9-((S)-1-((R)-5-(hydroxymethyl)-4-methyl-6-oxo-3,6-dihydro-2H-pyran-2-yl)ethyl)-9a,11b-dimethyl-5a,6,6a,6b,7,8,9,9a,10,11,11a,11b-dodecahydrocyclopenta[1,2]phenanthro[8a,9-b]oxiren-1(4H)-one
- Withaferin A-RM
- 5119-48-2
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Steroids
- antibiotic
