Pidolinsure
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- CAS-Nr.
- 98-79-3
- Bezeichnung:
- Pidolinsure
- Englisch Name:
- L-Pyroglutamic acid
- Synonyma:
- PYROGLUTAMIC ACID;H-PYR-OH;(S)-5-OXOPYRROLIDINE-2-CARBOXYLIC ACID;L-5-OXOPROLINE;5-oxoproline;oxoproline;5-Oxopyrrolidine-2-carboxylic acid;PYRROLIDONECARBOXYLIC ACID;PYR-OH;l-pyroglutamic
- CBNumber:
- CB9197008
- Summenformel:
- C5H7NO3
- Molgewicht:
- 129.11
- MOL-Datei:
- 98-79-3.mol
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Pidolinsure Eigenschaften
- Schmelzpunkt:
- 160-163 °C(lit.)
- Siedepunkt:
- 239.15°C (rough estimate)
- alpha
- -27.5 º (c=10, 1 N NaOH)
- Dichte
- 1.3816 (rough estimate)
- Dampfdruck
- 0.002Pa at 25℃
- Brechungsindex
- -10 ° (C=5, H2O)
- storage temp.
- 2-8°C
- L?slichkeit
- H2O: 1 M at 20 °C, clear, colorless
- Aggregatzustand
- Crystalline Powder
- pka
- 3.32(at 25℃)
- Farbe
- White to off-white
- PH
- 1.7 (50g/l, H2O, 20℃)
- Geruch (Odor)
- wh. crystal, odorless, sl. acidic taste
- Optische Aktivit?t
- [α]20/D 10.5±1°, c = 5% in H2O
- Wasserl?slichkeit
- 10-15 g/100 mL (20 ºC)
- Merck
- 14,8001
- BRN
- 82132
- Stabilit?t:
- Stable. Incompatible with bases, acids, strong oxidizing agents.
- LogP
- -1.233 at 20℃
- CAS Datenbank
- 98-79-3(CAS DataBase Reference)
- NIST chemische Informationen
- Pidolic acid(98-79-3)
- EPA chemische Informationen
- 5-Oxo-L-proline (98-79-3)
Pidolinsure Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
L-pyroglutamic acid has its scientific name being L-2-pyrrolidone-5-carboxylic acid. Precipitation from ethanol and petroleum ether mixture were colorless orthorhombic bipyramid crystals with the melting temperature being 162~163 °C. It is soluble in water, alcohol, acetone and acetic acid, slightly soluble in ethyl acetate, and insoluble in ether. Specific rotation-11.9 ° (c = 2, H2O). It is produced from 42% aqueous solution of glutamic acid which subjects to heating dehydration, concentration, crystallization, washing and drying to obtain L-pyroglutamic acid.
Verwenden
L-Pyroglutamic acid is an amino acid that is used in the synthesis of peptides. It has also been observed to convert when placed at the N-terminus in vivo to create IgG2 antibodies.
Definition
ChEBI: An optically active form of 5-oxoproline having L-configuration.
l?uterung methode
Crystallise S-pyroglutamic acid by dissolving it in boiling EtOH (20g in 100mL), cooling and after a few minutes additing pet ether (b 40-60o, 120mL), then after 5 minutes adding a further 120mL, and coThis has m 155.5-157.5o and [] D -11.4o (c 4.4, H2O) [Hardy Synthesis 290 1978, Pellegata et al. Synthesis 614 1978]. The NH4 salt has m 184-186o (from EtOH). [Beilstein 22/6 V 7.]
Pidolinsure Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Pidolinsure Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 726)Lieferanten
98-79-3(Pidolinsure)Verwandte Suche:
- (5s)-2-oxopyrrolidine-5-carboxylicacid
- (s)-5-oxo-2-pyrrolidinecarboxylicacid
- (s)-pyroglutamicacid
- 2-benzothiazolesulfenicacidmorpholide
- 2-l-pyrrolidone-5-carboxylicacid
- 2-oxopyrrolidine-5-carboxylicacid
- 2-pyrrolidone-5-carboxylate
- glutimicacid
- glutiminicacid
- l-glutamicacidgamma-lactam
- l-glutimicacid
- L-Glutiminoicacid
- L-Pyroglutamic acid-L-S-pyrrolidone-2-carboxylic acid
- L-Pyronglutamicacid
- l-pyrrolidinonecarboxylicacid
- l-pyrrolidonecarboxylicacid
- pidolicacid
- Pidolidone
- Proline, 5-oxo-
- pyrrolidinonecarboxylicacid
- pyrrolidone-5-carboxylicacid
- (2S)-5-Oxopyrrolidin-2-ylcarboxylic acid
- L-PYROGLUTAMIC ACID SIGMAULTRA
- H-Pyr-OH=L-2-Pyrrolidone-5-carboxylicacid
- Glutamic acid lactam
- α-Aminoglutaric acid lactam
- Pidolic
- L-PYROGLUTAMIC ACID ULTRA PURE, 99% EE
- L-PYRPGLUTAMICACID
- PYRROLIDONECARBOXYLATE
- L-Pyroglutamic acid, H-Pyr-OH
- (S)-(-)-2-Pyrrolidinone-5-carboxylic acid, 98+%
- L-Pyroglutamic acid, (S)-2-Pyrrolidone-5-carboxylic acid, (S)-5-Oxo-2-pyrrolidinecarboxylic acid
- 2-oxopyrrolidine-1-carboxylic acid
- L-Pyroglutamic acid≥ 99% (Titration: anhydrous basis)
- (S)-(-)-2-Pyrrolidone-5-carboxylic acid for synthesis
- L-GLUTIMINIC ACID
- L-GLUTAMIC ACID LACTAM
- (-)-L-PYROGLUTAMIC ACID
- L-PYROGLUTAMIC ACID
- L-2-PYRROLIDONE-5-CARBOXYLIC ACID
- L-5-CARBOXY-2-PYRROLIDINONE
- L-5-OXO-2-PYRROLIDINECARBOXYLIC ACID
- L-5-OXO-PYRROLIDINE CARBOXYLIC ACID
- L-5-PYRROLIDONE-2-CARBOXYLIC ACID
- L-A-AMINOGLUTARIC ACID LACTAM
- H-L-PGLU-OH
- H-L-PYROGLUTAMIC ACID
- H-PGLU-OH
- (S)-5-PYRROLIDONE-2-CARBOXYLIC ACID
- (S)-(-)-2-PYRROLIDINONE-5-CARBOXYLIC ACID
- (S)-2-PYRROLIDINE-5-CARBOXYLIC ACID
- (S)-(-)-2-PYRROLIDONE-5-CARBOXYLIC ACID
- (S)-2-PYRROLIDONE-5-CARBOXYLIC ACID
- RARECHEM EM WB 0204
- 5-OXO-2-PYRROLIDINECARBOXYLIC ACID
- 5-carboxy-2-pyrrolidinone
- 5-oxo-l-prolin