Sulfobernsteins?ure-bis-2-ethylhexylester, Natrium-Salz
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Sulfobernsteins?ure-bis-2-ethylhexylester, Natrium-Salz Eigenschaften
- Schmelzpunkt:
- 173-179 °C(lit.)
- Siedepunkt:
- 82.7°C
- Dichte
- 1.1
- Dampfdruck
- 0Pa at 25℃
- storage temp.
- Inert atmosphere,Room Temperature
- L?slichkeit
- methanol: 0.1 M at 20 °C, clear, colorless
- Aggregatzustand
- Waxy Solid
- Farbe
- White
- Wichte
- 1.005_PERCENT VOLATILE: 40
- Wasserl?slichkeit
- 1.5 g/100 mL (25 ºC)
- Sensitive
- Hygroscopic
- maximale Wellenl?nge (λmax)
- λ: 260 nm Amax: 0.1
λ: 280 nm Amax: 0.05
- Merck
- 14,3401
- BRN
- 4117588
- Stabilit?t:
- Stable. Combustible. Incompatible with strong oxidizing agents.
- InChIKey
- APSBXTVYXVQYAB-UHFFFAOYSA-M
- LogP
- 1.998 at 20℃
- CAS Datenbank
- 577-11-7(CAS DataBase Reference)
- EPA chemische Informationen
- Bis(2-ethylhexyl) sodium sulfosuccinate (577-11-7)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher | Xn,Xi | ||
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R-S?tze: | 22-38-41-36/37/38 | ||
S-S?tze: | 26-39-37/39-36 | ||
WGK Germany | 2 | ||
RTECS-Nr. | WN0525000 | ||
F | 3-10 | ||
TSCA | Yes | ||
HS Code | 29171900 | ||
Giftige Stoffe Daten | 577-11-7(Hazardous Substances Data) | ||
Toxizit?t | LD50 oral in rat: 1900mg/kg |
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Alarmwort | Achtung | |||||||||||||||||||||
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Sicherheit |
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Sulfobernsteins?ure-bis-2-ethylhexylester, Natrium-Salz Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.R38:Reizt die Haut.
R41:Gefahr ernster Augensch?den.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.S39:Schutzbrille/Gesichtsschutz tragen.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
white solid, often supplied as an aqueous solutionVerwenden
Dioctyl sulfosuccinate sodium salt is a wetting and emulsifying agent that is slowly soluble in water, having a solubility of 1 g in 70 ml of water. It functions as a wetting agent in fumaric acid-containing powdered fruit drinks to help the acid dissolve in water. It is used as a stabilizing agent on gums at not more than 0.5% by weight of the gum. It is used as a flavor potentiator in canned milk where it improves and maintains the flavor of the sterilized milk during storage. It also functions as a processing aid in the manufacture of unrefined sugar. It is also termed sodium dioctylsulfosuccinate.Vorbereitung Methode
Maleic anhydride is treated with 2-ethylhexanol to produce dioctyl maleate, which is then reacted with sodium bisulfite.Allgemeine Beschreibung
Odorless colorless to white waxy solid. Sinks and mixes slowly with water.Air & Water Reaktionen
Mixes slowly with water.Reaktivit?t anzeigen
Docusate sodium causes foaming and spreading of water. Assists in putting out fires by water. [USCG, 1999].Health Hazard
Liquid is strong irritant to eye and may irritate skin by removing natural oils. Ingestion causes diarrhea and intestinal bloating.Brandgefahr
Behavior in Fire: Causes foaming and spreading of water. Assists in putting out fires by water.Pharmazeutische Anwendungen
Docusate sodium and docusate salts are widely used as anionic surfactants in pharmaceutical formulations. Docusate sodium is mainly used in capsule and direct-compression tablet formulations to assist in wetting and dissolution.Sicherheitsprofil
Poison by intravenous route. Moderately toxic by ingestion and intraperitoneal routes. A skin and severe eye irritant. See also ESTERS. When heated to decomposition it emits toxic fumes of SOx and Na2O.Sicherheit(Safety)
Docusate salts are used in oral formulations as therapeutic agents for their fecal softening and laxative properties. As a laxative in adults, up to 500mg of docusate sodium is administered daily in divided doses; in children over 6 months old, up to 75 mg in divided doses is used. The quantity of docusate sodium used as an excipient in oral formulations should therefore be controlled to avoid unintended laxative effects. Adverse effects associated with docusate sodium include diarrhea, nausea, vomiting, abdominal cramps, and skin rashes. As with the chronic use of laxatives, the excessive use of docusate sodium may produce hypomagnesemia.Docusate salts are absorbed from the gastrointestinal tract and excreted in bile; they may cause alteration of the gastrointestinal epithelium. The gastrointestinal or hepatic absorption of other drugs may also be affected by docusate salts, enhancing activity and possibly toxicity. Docusate sodium should not be administered with mineral oil as it may increase the absorption of the oil.
LD50 (mouse, IV): 0.06 g/kg
LD50 (mouse, oral): 2.64 g/kg
LD50 (rat, IP): 0.59 g/kg
LD50 (rat, oral): 1.9 g/kg
Lager
Docusate sodium is stable in the solid state when stored at room temperature. Dilute aqueous solutions of docusate sodium between pH 1–10 are stable at room temperature. However, at very low pH (<1) and very high pH (>10) docusate sodium solutions are subject to hydrolysis.The solid material is hygroscopic and should be stored in an airtight container in a cool, dry place.
l?uterung methode
Dissolve it in MeOH and the inorganic salts which precipitate are filtered off. Water is added and the solution is extracted several times with hexane. The residue is evaporated to one-fifth its original volume, *benzene is added and azeotropic distillation is continued until no water remains. The solvent is evaporated. The white residual solid is crushed and dried in vacuo over P2O5 for 48hours [El Seoud & Fendler J Chem Soc, Faraday Trans 1 71 452 1975]. [Beilstein 4 IV 114.] It solubilises major myelin trans membrane proteolipids, and forms reverse micelles in hydrocarbon solvents.Inkompatibilit?ten
Electrolytes, e.g. 3% sodium chloride, added to aqueous solutions of docusate sodium can cause turbidity. However, docusate sodium possesses greater tolerance to calcium, magnesium, and other polyvalent ions than do some other surfactants. Docusate sodium is incompatible with acids at pH < 1 and with alkalis at pH > 10.Regulatory Status
GRAS listed. Included in the FDA Inactive Ingredients Database (IM injections; oral capsules, suspensions, and tablets; also topical formulations). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.Sulfobernsteins?ure-bis-2-ethylhexylester, Natrium-Salz Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Sulfobernsteins?ure-bis-2-ethylhexylester, Natrium-Salz Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 762)Lieferanten
Firmenname | Telefon | Land | Produktkatalog | Edge Rate | |
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Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 |
info@dycnchem.com | China | 52849 | 58 |
GIHI CHEMICALS CO.,LIMITED | +8618058761490 |
info@gihichemicals.com | China | 49977 | 58 |
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xie@china-sinoway.com | China | 988 | 58 |
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bess@weibangbio.com | China | 18148 | 58 |
Anhui Ruihan Technology Co., Ltd | +8617756083858 |
daisy@anhuiruihan.com | China | 973 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 20275 | 58 |
Shandong Juchuang Chemical Co., LTD | +undefined15030412209 |
admin@juchuangchem.com | China | 333 | 58 |
Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 |
admin@zlchemi.com | China | 3002 | 58 |
577-11-7(Sulfobernsteins?ure-bis-2-ethylhexylester, Natrium-Salz)Verwandte Suche:
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