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Cefdinir

Cefdinir Struktur
91832-40-5
CAS-Nr.
91832-40-5
Englisch Name:
Cefdinir
Synonyma:
Omnicef;Cefzon;CFDN;Omnice;FK-482;CI 983;Novacef;CEFDINIR;cefdinyl;bmy28488
CBNumber:
CB7483101
Summenformel:
C14H13N5O5S2
Molgewicht:
395.41
MOL-Datei:
91832-40-5.mol

Cefdinir Eigenschaften

Schmelzpunkt:
>180°C dec.
Dichte
1.89±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,2-8°C
L?slichkeit
dilute HCl: slightly soluble
pka
9.70(at 25℃)
Aggregatzustand
solid
Farbe
Pale Yellow to Light Yellow
Wasserl?slichkeit
Soluble in water
maximale Wellenl?nge (λmax)
295nm(DMSO)(lit.)
Merck 
14,1920
BCS Class
4
InChIKey
RTXOFQZKPXMALH-GHXIOONMSA-N
SMILES
N12[C@@]([H])([C@H](NC(/C(/C3=CSC(N)=N3)=N\O)=O)C1=O)SCC(C=C)=C2C(O)=O
CAS Datenbank
91832-40-5(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
WGK Germany  3
RTECS-Nr. XI0367250
HS Code  2941906000
Toxizit?t LD50 orl-rat: >5600 mg/kg IYKEDH 23,93,1992
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H317 Kann allergische Hautreaktionen verursachen. Sensibilisierung der Haut Kategorie 1A Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H334 Kann bei Einatmen Allergie, asthmaartige Symptome oder Atembeschwerden verursachen. Sensibilisierung der Atemwege Kategorie 1 Achtung GHS hazard pictogramssrc="/GHS08.jpg" width="20" height="20" /> P261, P285, P304+P341, P342+P311,P501
Sicherheit
P261 Einatmen von Staub vermeiden.
P272 Kontaminierte Arbeitskleidung nicht au?erhalb des Arbeitsplatzes tragen.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P284 Atemschutz tragen.
P501 Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

Cefdinir Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Cefdinir is an orally active, beta-lactamase stable cephalosporin with a broad spectrum of activity. Compared to other oral cephalosporins, cefdinir is more potent against Gram-positive bacteria, especially Staphylococci. Its activity against Gram-negative bacteria such as E.coli,K. pneumoniae and P.mirabilis is similar to cefixime, but superior to cefaclor and cephalexin.

Chemische Eigenschaften

Pale Yellow Solid

Verwenden

A Cephalosporin antibiotic structurally similar to Cefixime

Definition

ChEBI: A cephalosporin compound having 7beta-2-(2-amino-thiazol-4-yl)-2-[(Z)-hydroxyimino]-acetylamino- and 3-vinyl side groups.

Antimicrobial activity

An oral cephalosporin similar in structure to cefixime, but with a slightly modified side chain at the 7-amino position. Activity is similar to that of cefixime, but it is more active, especially against staphylococci. It is not hydrolyzed by staphylococcal or the common plasmid-mediated enterobacterial β-lactamases. An enhancing effect on phagocytosis has been demonstrated in vitro.
Oral absorption is about 35%. A 200 mg oral dose achieves a plasma concentration of 1 mg/L after c. 3 h. Absorption is reduced after a fatty meal. Concentrations equal to or higher than corresponding plasma levels were present in blister fluid 6–12 h after administration of an oral dose. The plasma halflife is 1.5 h. Protein binding is 60–70%. A total of 12–20% of the dose was excreted in the urine within 12 h, the renal elimination declining with increasing dose. The elimination half-life and peak plasma concentration are increased in renal failure. About 60% of the drug is removed by hemodialysis.
Side effects and uses are those common to oral cephalosporins.

Sicherheitsprofil

Moderately toxic by ingestion andintravenous routes. Low toxicity by intraperitoneal andsubcutaneous routes. Experimental reproductive effects.When heated to decomposition it emits toxic vapors ofNOx and SOx.

Cefdinir Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Cefdinir Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 482)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shenzhen Excellent Biomedical Technology Co.,Ltd.
+86-0755-26050679 +86-15915472436
sale@ex-biotech.cn China 1031 58
Hebei Jingbo New Material Technology Co., Ltd
+8619931165850
hbjbtech@163.com China 1000 58
Hebei Saisier Technology Co., LTD
+86-18400010335 +86-18034520335
admin@hbsaisier.cn China 1015 58
Shaanxi TNJONE Pharmaceutical Co., Ltd
+8618092446649
sarah@tnjone.com China 1143 58
Hebei Longbang Technology Co., LTD
+86-18633929156 +86-18633929156
admin@hblongbang.com China 941 58
HebeiShuoshengImportandExportco.,Ltd
+86-18532138899 +86-18532138899
L18532138899@163.com China 939 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806
sales@capot.com China 29791 60
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21634 55
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29880 58
Hubei Jusheng Technology Co.,Ltd.
18871490254
linda@hubeijusheng.com CHINA 28172 58

91832-40-5()Verwandte Suche:


  • (6r-(6-alpha,7-beta(z)))-)(hydroxyiminoacetyl)amino)-3-ethenyl-8-oxo
  • bmy28488
  • cefdinyl
  • 8-[2-(2-amino-1,3-thiazol-4-yl)-1-hydroxy-2-nitroso-ethenyl]amino-4-ethenyl-7-oxo-2-thia-6-azabicyclo[4.2.0]oct-4-ene-5-carboxylicacid
  • 7-[2-(2-AMINOTHIAZOL-4-YL)-2-HYDROXYIMINOACETYLAMINO]-8-OXO-3-VINYL-5-THIA-1-AZA-BICYCLO[4.2.0]OCT-2
  • (6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)(hydroxyimino)acetyl]amino]-3-ethenyl-8-oxo--5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid
  • FK-482
  • Omnice
  • CEFDIRNIR
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(hydroxyimino)acetyl]amino]-3-ethenyl-8-oxo-, [6R-[6a,7b(Z)]]-
  • CEFDINIR
  • PD 134393
  • [6R-[6α-7beta(Z)]]-7-[[(2-Amino-4-thiazolyl)(hydroxyimino)acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • syn-7-[2-(2-amino-4-thiazolyl)-2-hydroxyiminoacetamido]-3-vinyl-3-cephem-4-carboxylic acid
  • Cefdinir, >=97%
  • Cefdinir API
  • Novacef
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(hydroxyimino)acetyl]amino]-3-ethenyl-8-oxo-, (6R,7R)-
  • CFDN
  • CI 983
  • BMY-28488, FK-482, syn-7-[2-(2-amino-4-thiazolyl)-2-hydroxyiminoacetamido]-3-vinyl-3-cephem-4-carboxylic acid, [6R-[6α-7beta(Z)]]-7-[[(2-Amino-4-thiazolyl)(hydroxyimino)acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • [6R-[6α,7β(Z)]]_7-[[(2-Amino-4-thiazolyl)(hydroxyimino)acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • (6R,7R)-7-[[2-(2-amino-1,3-thiazol-4-yl)-2-hydroxyimino-acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)(hydroxyimino acetyl)amino)-3-ethenyl-8-oxo-, (6R-(6-alpha,7-beta(Z)))-
  • (6R,7R)-3-Vinyl-7-[(2-amino-4-thiazolyl)[(Z)-hydroxyimino]acetylamino]-8-oxo-5-thia-1-azabicyclo[4.2.0]octa-2-ene-2-carboxylic acid
  • (6R,7R)-7α-[[(2-Amino-4-thiazolyl)[(Z)-hydroxyimino]acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • Cefdinir (200 mg)
  • Cefdinir (300 mg)
  • (6R,7R)-7-[(2Z)-2-(2-aMino-1,3-thiazol-4-yl)-2-(N-hydroxyiMino)acetaMido]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • (6R,7R)-7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(hydroxyimino)acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • (6R,7R)-7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-hydroxyimino-1-oxoethyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • Cefdinir >
  • Cefdinir Cefdinir
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(hydroxyimino)acetyl]amino]-3-ethenyl-8-oxo-, (6R,7R)-
  • (6R,7R)-7-((Z)-2-(2-Aminothiazol-4-yl)-2-(hydroxyimino)acetamido)-8-oxo-3-vinyl-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • Cefdinir USP/EP/BP
  • Cefdinir (Unlabelled)
  • Cefdinir (FK-482
  • Cefdinir 15N2,13CQ: What is Cefdinir 15N2,13C Q: What is the CAS Number of Cefdinir 15N2,13C Q: What is the storage condition of Cefdinir 15N2,13C Q: What are the applications of Cefdinir 15N2,13C
  • CefdinirQ: What is Cefdinir Q: What is the CAS Number of Cefdinir Q: What is the storage condition of Cefdinir Q: What are the applications of Cefdinir
  • TIANFUCHEM--91832-40-5--High purity Cefdinir factory price
  • Cefdinir (1097614)
  • Omnicef
  • To cephalosporin,
  • Cefzon
  • cefdinil
  • Cefdinib
  • Cefodinir
  • 91832-40-5
  • 1832-40-5
  • C14H13N5O5S2
  • cephalosporins
  • Chiral Reagents
  • ACEON
  • Miscellaneous Biochemicals
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Sulfur & Selenium Compounds
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