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1,3-Dihydro-3-oxoisobenzofuran-1-ylidenbis(6-hydroxy-5-methyl-m-phenylenmethylennitrilo)tetraessigsure

o-Cresolphthalein Complexone Struktur
2411-89-4
CAS-Nr.
2411-89-4
Bezeichnung:
1,3-Dihydro-3-oxoisobenzofuran-1-ylidenbis(6-hydroxy-5-methyl-m-phenylenmethylennitrilo)tetraessigsure
Englisch Name:
o-Cresolphthalein Complexone
Synonyma:
PC;O-CPC;exone;ein CompL;Nsc 298195;Cresolphtha;METAL PHTHALEIN;METAL PHTHALEINE;METALPHTHALEIN 1;PHTHALEIN PURPLE
CBNumber:
CB6431655
Summenformel:
C32H32N2O12
Molgewicht:
636.61
MOL-Datei:
2411-89-4.mol

1,3-Dihydro-3-oxoisobenzofuran-1-ylidenbis(6-hydroxy-5-methyl-m-phenylenmethylennitrilo)tetraessigsure Eigenschaften

Schmelzpunkt:
181-185 °C (dec.)(lit.)
Siedepunkt:
892.1±65.0 °C(Predicted)
Dichte
1.515±0.06 g/cm3(Predicted)
chüttdichte
50kg/m3
storage temp. 
Store below +30°C.
L?slichkeit
NaOH: soluble50mg/mL
Aggregatzustand
Powder
pka
1.47, 8.24(at 25℃)
Farbe
white to off-white
S?ure-Base-Indikators(pH-Indikatoren)
Colorless (8.2) to red (9.8)
Wasserl?slichkeit
SLIGHTLY SOLUBLE
maximale Wellenl?nge (λmax)
575nm, 377nm
BRN 
381994
Stabilit?t:
Stable. Incompatible with strong oxidizing agents.
Major Application
Sensors, photoconductors, copying materials, rubber, body fiuid testing, determination of calcium, magnesium, tin, method for measuring urea nitrogen, liposomal construct for diagnostic use, cardiovascular disease, antibacterial agent
InChIKey
IYZPEGVSBUNMBE-UHFFFAOYSA-N
EPA chemische Informationen
Glycine, N,N'-[(3-oxo-1(3H)-isobenzofuranylidene)bis[(6-hydroxy-5-methyl-3,1-phenylene)methylene]]bis[N-(carboxymethyl)- (2411-89-4)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xn
R-S?tze: 20/21/22-36/37/38
S-S?tze: 22-24/25-36-26
WGK Germany  3
TSCA  Yes
HS Code  29322980
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

1,3-Dihydro-3-oxoisobenzofuran-1-ylidenbis(6-hydroxy-5-methyl-m-phenylenmethylennitrilo)tetraessigsure Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R20/21/22:Gesundheitssch?dlich beim Einatmen,Verschlucken und Berührung mit der Haut.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-S?tze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.

Chemische Eigenschaften

White powder

Verwenden

Indicator for complexometric titration of Mg, Ca, Sr and Ba. It is used as an alkaline earth metal ion indicator. Suggested to be colorless at pH 11, but turns pink in the presence of alkaline earth metals. Also utilized in an auto analyzer to determine serum calcium.

l?uterung methode

o-Cresolphthalein (a complexon precursor without the two bis-carboxymethylamino groups) is a contaminant and is one of the starting materials. It can be removed by dissolving the reagent in H2O and adding a 3-fold excess of sodium acetate and fractionally precipitating it by dropwise addition of HCl to the clear filtrate. Wash the precipitate with cold H2O and dry the monohydrate at 30o in a vacuum. The pure material gives a single spot on paper chromatography (eluting solvent EtOH/water/phenol, 6:3:1, and developing with NaOH). [Anderegg et al. Helv Chim Acta 37 113 1954.] It complexes with Ba, Ca, Cd, Mg and Sr. [Beilstein 18 III/IV 8141.]

1,3-Dihydro-3-oxoisobenzofuran-1-ylidenbis(6-hydroxy-5-methyl-m-phenylenmethylennitrilo)tetraessigsure Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


1,3-Dihydro-3-oxoisobenzofuran-1-ylidenbis(6-hydroxy-5-methyl-m-phenylenmethylennitrilo)tetraessigsure Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 319)Lieferanten
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2411-89-4(1,3-Dihydro-3-oxoisobenzofuran-1-ylidenbis(6-hydroxy-5-methyl-m-phenylenmethylennitrilo)tetraessigsure)Verwandte Suche:


  • O-CRESOLPHTHALEIN COMPLEXON
  • O-CRESOLPHTHALEIN COMPLEXONE
  • O-CRESOLPHTHALEXON
  • O-CRESOLPHTHALEXONE
  • O-CRESOLPHTHALEINDI-(METHYLIMINODI-ACETIC ACID)
  • CRESOLPHTHALEIN-BISMETHYLIMINODIACETIC ACID
  • CRESOLPHTHALEIN COMPLEXONE
  • CRESOL PHTHALEXONE
  • METAL PHTHALEIN
  • METALPHTHALEIN 1
  • METAL PHTHALEINE
  • PHTHALEIN PURPLE INDICATOR FOR METALTITR ATION
  • O-CRESOLPHTHALEIN COMPLEXON, INDICATOR F OR COMPLEXOMETRY
  • O-CresolphtnaleinComplexone
  • O-CresolphthaleineComplexone
  • O-CresolphthaleinComplexone-(MetalPhthalein,PhthaleinPurple,O-Cresolphthlexon)
  • O-CRESOLPHTHALEIN COMPLEXONE INDIC (PHTHALEIN COMPLEXON)
  • PHTHALEIN COMPLEXON(CHELATING INDIC)SU
  • o-Cresolphthalein Complexone, pure
  • 1,3-dihydro-3-oxoisobenzofuran-1-ylidenebis(6-hydroxy-5-methyl-m-phenylenemethylenenitrilo)tetra-acetic acid
  • o-Cresolphthalexon~Phthalein complexone
  • PC
  • 3,3'-BIS[N,N-BIS(CARBOXYMETHYL)AMINOMETHYL]-O-CRESOLPHTHALEIN
  • METALPHTHALEIN REAGENT (ACS)
  • o-cresolphthalein complexone, indicator grade
  • 2-cresolphthalexon
  • 3',3"-Bis[[bis(carboxymethyl)amino]methyl]-5', 5"-dimethylphenolphthalein
  • Phthalein Complexon [Chelating Indicator]
  • enylene)methylene]]bis[n-(carboxymethyl)-
  • glycine,n,n’-[(3-oxo-1(3h)-isobenzofuranylidene)bis[(6-hydroxy-5-methyl-3,1-ph
  • N,N’-[(3-oxo-1(3H)-isobenzofuranylidene]bis[(6-hydroxy-5-methyl-3,1-phenylene)methylene)]bis(n-(cGlycine
  • XYLENOLPHTHALEIN-BIS(MINODIACETIC ACID)
  • XYLENYLPHTHALEIN-BISIMINODIACETIC ACID
  • PHTHALEIN PURPLE
  • PHTHALEIN COMPLEXON
  • PHTHALEIN COMPLEXONE
  • O-CRESOLPHTHALEIN-3',3''-BIS-METHYLENEIMINODIACETIC ACID
  • o-Cresolphthalein Complexone(R)
  • o-Cresolphthalexon, Metal phthalein, Phthalein purple, Xylenylphthalein-bisiminodiacetic acid, o-Cresolphthalein-3μ,3μμ-bis-methyleneiminodiacetic acid
  • Metalphthalein, Reagent
  • 2-[[5-[1-[3-[(Bis(carboxymethyl)amino)methyl]-4-hydroxy-5-methyl-phenyl]-3-oxo-isobenzofuran-1-yl]-2-hydroxy-3-methyl-phenyl]methyl-(carboxymethyl)amino]acetic acid
  • Cresolphthalexon
  • Glycine, N,N'-[(3-oxo-1(3H)-isobenzofuranylidene)bis[(6-hydroxy-5-methyl-3,1-phenylene)methylene]]bis[N-(carboxymethyl)-
  • Cresolphtha
  • o-Cresolphthalein complexone p.a.
  • o-Cresolphthalein Co
  • Metalphthalein, n-hydrate
  • o-Cresolphthalein CoMplexone, pure 5GR
  • Cresolphthalein-bismethyliminodiacetic Acid o-Cresolphthalein Complexon Metal Phthalein Phthalein Purple
  • PHTHALEIN PURPLE METAL INDICATOR
  • o-Cresolphthalein coMplexone, ACS reagent, indicator
  • o-Cresolphthalein Complexon 〔Phthalein Complexon〕
  • Phenolphthalein, 3′,3′′-bis[[bis(carboxymethyl)amino]methyl]-5′,5′′-dimethyl-
  • 3,3′-bis[n,n-di(carboxymethyl)amino-methyl]-o-cresolphthalein
  • Cresolphthalein Complexon
  • Nsc 298195
  • Phthalein purple metal indicator Reag. Ph Eur
  • O-CRESOLPHTHALEIN-3',3''-BIS(METHYLIMINODI-ACETIC ACID)
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