Methazolamid Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R20/21/22:Gesundheitssch?dlich beim Einatmen,Verschlucken und Berührung mit der Haut.
R40:Verdacht auf krebserzeugende Wirkung.

S-S?tze Betriebsanweisung:

S22:Staub nicht einatmen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

Beschreibung

Methazolamide is a carbonic anhydrase inhibitor (IC₅₀ = 130 nM). It reduces intraocular pressure and cerebrospinal fluid flow in a rat model of glaucoma. Methazolamide reduces electroshock-induced seizures in rats with an ED₅₀ value of 19.2 mg/kg. It also inhibits production of reactive oxygen species (ROS) in a primary cortical neuron (PCN) cellular model of subarachnoid hemorrhage (SAH) and reduces cerebral edema in a mouse model of SAH. Methazolamide is larvicidal, with a larvicidal concentration (LC₅₀) value of 724 ppm, but has no activity when administered in the diet to adult A. aegypti. Formulations containing methazolamide have been used for the treatment of glaucoma.

Chemische Eigenschaften

White Solid

Verwenden

Methazolamide is a carbonic anhydrase inhibitor. Methazolamide is used in the treatment of glaucoma.

Clinical Use

Methazolamide is a derivative of acetazolamide in which one of the active hydrogens has been replaced by a methyl group. This decreases the polarity and permits a greater penetration into the ocular fluid, where it acts as a carbonic anhydrase inhibitor, reducing intraocular pressure. Its dose for glaucoma is 50 to 100 mg two to three times a day.

Methazolamid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Methazolamid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3009	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29880	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
Xiamen AmoyChem Co., Ltd	+86-86-5926051114 +8618959220845	sales@amoychem.com	China	6383	58
HubeiwidelychemicaltechnologyCo.,Ltd	18627774460	faith@widelychemical.com	CHINA	742	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39894	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49374	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
Win-Win chemical CO., Limited	+86-0086-577-64498589 +86-15355981851	sales@win-winchemical.com	China	14426	58

554-57-4(Methazolamid)Verwandte Suche:

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• 2-acetylimino-3-methyl-delta(sup4)-1,3,4-thiadiazoline-5-sulfonamide
• 2-Acetylimino-3-methyl-delta⁴-1,3,4-thiadiazoline-5-sulfonamide
• 5-acetylimino-4-methyl-delta(sup2)-1,3,4-thiadiazoline-2-sulfonamide
• CL 8490
• N-[5-(Aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene]acetamide
• N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2-ylidene)acetamide
• N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2-ylidene)ethanamide
• Methazolamide (500 mg)
• MethazolaMide, USP
• 5-AcetyliMino-4-Methyl-Δ2-1,3,4-thiadiazoline-2-sulfonaMide
• L 584601
• Neptaza
• n-(4-methyl-2-sulfamoyl-△2-1,3,4-thiadiazolin-5-ylidene) acetamide
• N-[(2E)-5-(Aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene]acetamide
• (E)-N-(3-Methyl-5-sulfaMoyl-1,3,4-thiadiazol-2(3H)-ylidene)acetaMide
• Methazolamide≥ 98% (HPLC)
• Carbonic Anhydrase IX Inhibitor III, Methazolamide
• Mathazolamide
• Methazolamide, >=99%
• 5-Acetylimino-4-methyl-delta²-1,3,4-thiadiazoline-2-sulfonamide
• Acetamide, N-(4-methyl-2-sulfamoyl-delta²-1,3,4-thiadiazolin-5-ylidene)-
• Acetamide, N-[5-(aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene]-
• Methenamide
• N-((2Z)-5-(Aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene)acetamide
• n-(4-methyl-2-sulfamoyl-delta(2)-1,3,4-thiadiazolin-5-ylidene)-acetamid
• n-(4-methyl-2-sulfamoyl-delta(sup2)-1,3,4-thiadiazolin-5-ylidene)-acetamid
• N-(4-Methyl-2-sulfamoyl-delta²-1,3,4-thiadiazolin-5-ylidene)acetamide
• n-(5-(aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3h)-ylidene)-acetamid
• Naptazane
• Neptazane
• Neptazaneat
• METHAZOLAMIDE
• N-[4-METHYL-2-SULFAMOYL-DELTA2-1,3,4-THIADIAZOLIN-5-YLIDENE] ACETAMIDE
• N-(3-Methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-2-ylidene)-acetamide
• Carbonic Anhydrase IX Inhibitor III, Methazolamide - CAS 554-57-4 - Calbiochem
• Methazolamide USP/EP/BP
• N-(3-Methyl-5-sulfamoyl-1,3,4-thiadiazol-2(3H)-ylidene)acetamide
• MethazolamideQ: What is Methazolamide Q: What is the CAS Number of Methazolamide Q: What is the storage condition of Methazolamide Q: What are the applications of Methazolamide
• Methazolamide (1406005)
• Methazolamid
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• C5H8N4O3S2
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