Polyethylene Glycol
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Polyethylene Glycol Eigenschaften
- Schmelzpunkt:
- 64-66 °C
- Siedepunkt:
- >250°C
- Tg
- -67
- Dichte
- 1.27 g/mL at 25 °C
- Dampfdichte
- >1 (vs air)
- Dampfdruck
- <0.01 mm Hg ( 20 °C)
- Brechungsindex
- n
20/D 1.469
- Flammpunkt:
- 270 °C
- storage temp.
- 2-8°C
- L?slichkeit
- H2O: 50 mg/mL, clear, colorless
- Aggregatzustand
- waxy solid
- Farbe
- White to very pale yellow
- Wichte
- 1.128
- PH
- 5.5-7.0 (25℃, 50mg/mL in H2O)
- Wasserl?slichkeit
- Soluble in water.
- Sensitive
- Hygroscopic
- maximale Wellenl?nge (λmax)
- λ: 260 nm Amax: 0.6
λ: 280 nm Amax: 0.3
- Merck
- 14,7568
- Stabilit?t:
- Stable. Incompatible with strong oxidizing agents.
- LogP
- -0.698 at 25℃
- NIST chemische Informationen
- Polyethylene glycol(25322-68-3)
- EPA chemische Informationen
- Polyethylene glycol (25322-68-3)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher | Xi,T | ||
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R-S?tze: | 36/38-52/53-33-23/24/25 | ||
S-S?tze: | 26-36-24/25-61-45-36/37 | ||
WGK Germany | 3 | ||
RTECS-Nr. | TQ4110000 | ||
F | 3-9 | ||
Selbstentzündungstemperatur | 581 °F | ||
Hazard Note | Harmful | ||
TSCA | Yes | ||
HS Code | 39072011 | ||
Giftige Stoffe Daten | 25322-68-3(Hazardous Substances Data) | ||
Toxizit?t | LD50 orally in Rabbit: 28000 mg/kg LD50 dermal Rabbit > 20000 mg/kg |
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Alarmwort | Achtung | |||||||||||||||||||||||||||||||||||
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Sicherheit |
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Polyethylene Glycol Chemische Eigenschaften,Einsatz,Produktion Methoden
ERSCHEINUNGSBILD
FARBLOSE, VISKOSE, LEICHT HYGROSKOPISCHE FLüSSIGKEIT.ARBEITSPLATZGRENZWERTE
TLV nicht festgelegt (ACGIH 2005).MAK: (Einatembare Fraktion) 1000 mg/m? Spitzenbegrenzung: überschreitungsfaktor II(8); Schwangerschaft: Gruppe C; (DFG 2005).
INHALATIONSGEFAHREN
Eine bel?stigende Partikelkonzentration in der Luft kann beim Dispergieren schnell erreicht werden.LECKAGE
Ausgelaufene Flüssigkeit in abgedeckten Beh?ltern sammeln. Verschüttete Flüssigkeit mit viel Wasser wegspülen.R-S?tze Betriebsanweisung:
R36/38:Reizt die Augen und die Haut.S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Beschreibung
Polyethylene glycols are a family of linear polymers formed by a base-catalyzed condensation reaction with repeating ethylene oxide units being added to ethylene. The molecular formula is (C2H4O)multH2O where mult denotes the average number of oxyethylene groups. The molecular weight can range from 200 to several million corresponding to the number of oxyethylene groups. The higher-molecular-weight materials (100 000 to 5 000 000) are also referred to as polyethylene oxides. The average molecular weight of any specific polyethylene glycol product falls within quite narrow limits (°5%). The number of ethylene oxide units or their approximate molecular weight (e.g., PEG-4 or PEG-200) commonly designates the nomenclature of specific polyethylene glycols. Polyethylene glycols with amolecular weight less than 600 are liquid, whereas those of molecular weight 1000 and above are solid. These materials are nonvolatile, water-soluble, tasteless, and odorless. They are miscible with water, alcohols, esters, ketones, aromatic solvents, and chlorinated hydrocarbons, but immiscible with alkanes, paraffins, waxes, and ethers.Chemische Eigenschaften
White waxy crystalline flakesVerwenden
Used in conjunction with carbon black to form a conductive composite.1 Polymer nanospheres of poly(ethylene glycol) were used for drug delivery.2Definition
Any of several condensa-tion polymers of ethylene glycol with thegeneral formula HOCH2(CH2OCH2)nCH2OH orH(OCH2CH2)nOH. Average molecular weightsrange from 200 to 6000. Properties vary with molec-ular weight.Vorbereitung Methode
Polyethylene glycol polymers are formed by the reaction of ethylene oxide and water under pressure in the presence of a catalyst.Indications
Polyethylene glycol (Miralax) is another osmotic laxative that is colorless and tasteless once it is mixed.Allgemeine Beschreibung
Clear colorless viscous liquid.Air & Water Reaktionen
Water soluble.Reaktivit?t anzeigen
Poly(ethylene glycol) is heat-stable and inert to many chemical agents; Poly(ethylene glycol) will not hydrolyze or deteriorate under normal conditions. Poly(ethylene glycol) has a solvent action on some plastics.Brandgefahr
Poly(ethylene glycol) is combustible.Sicherheitsprofil
When heated to decomposition it emits acrid smoke and irritating fumes.Environmental Fate
Like other polymeric substances, polyethylene glycols are not readily biodegradable, with reported 5-day biochemical oxygen demand (BOD5) of 0–1%. However, owing to their hydrophilicity, they have a low potential to bioaccumulate.Lager
Polyethylene glycols are chemically stable in air and in solution, although grades with a molecular weight less than 2000 are hygroscopic. Polyethylene glycols do not support microbial growth, and they do not become rancid.Polyethylene glycols and aqueous polyethylene glycol solutions can be sterilized by autoclaving, filtration, or gamma irradiation.
Sterilization of solid grades by dry heat at 150℃ for 1 hour may induce oxidation, darkening, and the formation of acidic degradation products. Ideally, sterilization should be carried out in an inert atmosphere. Oxidation of polyethylene glycols may also be inhibited by the inclusion of a suitable antioxidant.
If heated tanks are used to maintain normally solid polyethylene glycols in a molten state, care must be taken to avoid contamination with iron, which can lead to discoloration. The temperature must be kept to the minimum necessary to ensure fluidity; oxidation may occur if polyethylene glycols are exposed for long periods to temperatures exceeding 50℃. However, storage under nitrogen reduces the possibility of oxidation.
Polyethylene glycols should be stored in well-closed containers in a cool, dry place. Stainless steel, aluminum, glass, or lined steel containers are preferred for the storage of liquid grades.
Inkompatibilit?ten
The chemical reactivity of polyethylene glycols is mainly confined to the two terminal hydroxyl groups, which can be either esterified or etherified. However, all grades can exhibit some oxidizing activity owing to the presence of peroxide impurities and secondary products formed by autoxidation.Liquid and solid polyethylene glycol grades may be incompatible with some coloring agents.
The antibacterial activity of certain antibiotics is reduced in polyethylene glycol bases, particularly that of penicillin and bacitracin. The preservative efficacy of the parabens may also be impaired owing to binding with polyethylene glycols.
Physical effects caused by polyethylene glycol bases include softening and liquefaction in mixtures with phenol, tannic acid, and salicylic acid. Discoloration of sulfonamides and dithranol can also occur, and sorbitol may be precipitated from mixtures. Plastics, such as polyethylene, phenolformaldehyde, polyvinyl chloride, and cellulose-ester membranes (in filters) may be softened or dissolved by polyethylene glycols. Migration of polyethylene glycol can occur from tablet film coatings, leading to interaction with core components.
Regulatory Status
Included in the FDA Inactive Ingredients Database (dental preparations; IM and IV injections; ophthalmic preparations; oral capsules, solutions, syrups, and tablets; rectal, topical, and vaginal preparations). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.Polyethylene Glycol Upstream-Materialien And Downstream Produkte
Upstream-Materialien
n-Hexan
Ethylenoxid
Aluminiumtriisopropanolat
Polyethylene
DOYLE DIRHODIUM CATALYST-RH2(4S-MEOX)4
Solvent oil No.120
Kaliumhydroxid
Downstream Produkte
polyoxyethylene glycol (600) bislaurate
softener PEG
Water-soluble resin
softening agent PEN
Fatty alcohol polyoxyethylene ether N=3
4-(Indol-3-yl)butters?ure
5-Diethylamino-2-(5-brom-2-pyridylazo)phenol
Polyoxyethylene stearate
finishing agent based on water dispersed polysiloxang polyurethane block copolymers
Polyacrylonitrile fiber oil
DIETHOFENCARB
antistatic finish agent for synthetic fiber
rennin B
4-Fluoranilin
Antistatic finishing agent
Polypropylene
Thienamycin
efficient defoaming agent JC-5
C-1 acidic copper plating brightener
Polyethylene Glycol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 1134)Lieferanten
Firmenname | Telefon | Land | Produktkatalog | Edge Rate | |
---|---|---|---|---|---|
ChemFine International Co.,Ltd. | +86-510-82753588 +86-13806194144 |
info@chemfineinternational.com | China | 300 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 |
sales@tnjchem.com | China | 34563 | 58 |
Biopole Pharmatech Co., Ltd. | +8615151475053 |
biopole@163.com | China | 37 | 58 |
WUHAN JADECHEM INTERNATIONAL TRADE CO.,LTD | +86-83527060 +86-13972901456 |
sales03@jadechem-intl.com | China | 84 | 58 |
Yujiang Chemical (Shandong) Co.,Ltd. | +86-17736087130 +86-18633844644 |
catherine@yjchem.com.cn | China | 990 | 58 |
Hebei Weibang Biotechnology Co., Ltd | +8615531157085 |
abby@weibangbio.com | China | 8810 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 |
sales1@chuanghaibio.com | China | 5889 | 58 |
Sinoway Industrial co., ltd. | 0592-5800732; +8613806035118 |
xie@china-sinoway.com | China | 988 | 58 |
Hebei Weibang Biotechnology Co., Ltd | +8617732866630 |
bess@weibangbio.com | China | 18151 | 58 |
Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 |
lisa@kingfinertech.com | China | 3010 | 58 |
25322-68-3()Verwandte Suche:
Polyethylene glycol dimethyl ether
2-Propens?ure-1,2-ethandiylester
Poly(ethylene)
Ethylendistearat
Ethylendi(acetat)
Ethylencarbonat
2-Methylpentan-2,4-diol
OCTYLPHENYLPOLYETHYLENE GLYCOL
Butan-1,4-diol
1,2-Dibromethan
Ethylenoxid
2,2'-(Ethylenedioxy)diethanol
Diethylenglykol
Ethandiol
Methoxypolyethylene glycols
C8E3
Ethylen
PROPYLENE GLYCOL
- 2-ethanediyl),.alpha.-hydro-.omega.-hydroxy-Poly(oxy-1
- Alcox E 160
- Alcox E 30
- Poly(ethylene oxide),approx. M.W. 900,000
- POLYETHYLENE GLYCOL 1550PRACT.
- Poly(ethylene glycol),Macrogol 35,000, PEG
- Poly(ethylene glycol),Macrogol 3,000, PEG
- Poly(ethylene glycol),Macrogol 300, PEG
- Polyethylene glycol solution,PEG solution
- Polyethylene glycol 200, synthesis grade
- PEG 600 5g [25322-68-3]
- PEG 1000 1g [25322-68-3]
- 500 G POLYETHYLENE GLYCOL 1550PRACT.
- Poly(ethylene oxide),PEO
- Polyethylene Oxide (100 mg)
- Polyethylene glycol, MW ≈ 6,000
- Polyethylene glycol, MW ≈ 4,000
- alkapolpeg-8000
- alpha,omega-Hydroxypoly(ethylene oxide)
- alpha-Hydro-omega-hydroxypoly(oxy-1,2-ethanediyl)
- alpha-hydro-omega-hydroxy-poly(oxy-2-ethanediyl)
- alpha-Hydro-omega-hydroxypoly(oxyethylene)
- Bradsyn PEG
- bradsynpeg
- Carbowax 100
- Carbowax 1500
- Carbowax 1540
- Carbowax 20
- Carbowax 200
- Carbowax 2OM
- Carbowax 300
- Carbowax 5000
- Carbowax 550
- Carbowax 600
- Carbowax 6000
- Carbowax E-9000
- carbowax10000
- Ethylene polyoxide
- ethyleneglycolhomopolymer
- ethyleneglycolpolymer
- ethyleneoxide,homopolymer
- ethylenepolyoxide
- Gafanol E 200
- Gafanol E 300
- gafanole200
- Glycols, polyethylene
- glycols,polyethylene
- HM 500
- hm500
- jorchem400ml
- Laprol 402
- Lineartop P
- M 9000
- macrogol1000
- Merpol OJ
- merpoloj
- Modopeg
- Modopeg 4000