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N,N-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride

N,N-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride Struktur
149409-57-4
CAS-Nr.
149409-57-4
Englisch Name:
N,N-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride
Synonyma:
NE-100;NE100 HCl;NE100;NE 100;NE 100 hydrochloride;4-Methoxy-3-(2-phenylethoxy)-N,N-dipropylbenzeneethanaMine;4-Methoxy-3-(2-phenylethoxy)-N,N-dipropylbenzeneethanaminehydrochloride;N,N-Di-n-propyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl] ethylamine hydrochloride;N,N-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride;NE100 hydrochloride?,NE100,inhibit,Inhibitor,NE 100 hydrochloride?,Sigma Receptor,NE 100,NE-100
CBNumber:
CB61400997
Summenformel:
C23H33NO2.HCl
Molgewicht:
0
MOL-Datei:
149409-57-4.mol

N,N-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride Eigenschaften

Schmelzpunkt:
94-96°C
storage temp. 
2-8°C
L?slichkeit
H2O: soluble15mg/mL, clear
Aggregatzustand
powder
Farbe
white to beige
Stabilit?t:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.

Sicherheit

WGK Germany  3

N,N-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

NE-100 is a potent and selective σ1 receptor antagonist.

Biologische Aktivit?t

Potent and selective σ 1 receptor antagonist (K i = 0.86 nM) that displays > 55-fold selectivity over σ 2 receptors and > 6000-fold selectivity over D 1 , D 2 , 5-HT 1A , 5-HT 2 and PCP receptors. Exhibits reversible binding (K d = 1.2 nM) and displays antipsychotic activity in vivo . Orally active.

Biochem/physiol Actions

NE-100 is a potent and selective σ1 receptor antagonist with an IC50 value of 1.54 +/- 0.26 nM for σ1 receptors, > 55-fold selectivity over σ2 receptors and > 6000-fold selectivity over D1, D2, 5-HT1A, 5-HT2 and PCP receptors.

N,N-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

N,N-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 52)Lieferanten
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ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
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Aladdin Scientific 		+1-+1(833)-552-7181
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3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
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Changzhou Renaissance Chem Co. Ltd 86-519-86202821
China 116 56
Nanjing Chalf-Pharm Technology Co., Ltd. 025-57018978 18251899859
 sales@chalf-pharm.com China 5799 50

149409-57-4()Verwandte Suche:

  • N,N-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride
  • 4-Methoxy-3-(2-phenylethoxy)-N,N-dipropylbenzeneethanaminehydrochloride
  • NE 100 hydrochloride
  • N,N-Di-n-propyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl] ethylamine hydrochloride
  • NE-100
  • 4-Methoxy-3-(2-phenylethoxy)-N,N-dipropylbenzeneethanaMine
  • NE100;NE 100
  • NE100 HCl
  • NE100 hydrochloride?,NE100,inhibit,Inhibitor,NE 100 hydrochloride?,Sigma Receptor,NE 100,NE-100
  • 149409-57-4
  • C23H33NO2HCl
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