1-Desoxy-1-(methylamino)-D-glucitol-2-[2-methyl-3-(perfluormethyl)anilino]nicotinat
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- CAS-Nr.
- 42461-84-7
- Bezeichnung:
- 1-Desoxy-1-(methylamino)-D-glucitol-2-[2-methyl-3-(perfluormethyl)anilino]nicotinat
- Englisch Name:
- Flunixin meglumine
- Synonyma:
- flunixin meglumin;Flunixin Meglunine;1-deoxy-1-(methylamino)-d-glucito2-((2-methyl-3-(trifluoromethyl)phenyl)am;BANAMINE;Finadyne;Equileve;NIH 10250;fluixi egluie;IliuM Flunixil;lunixinmeglumine
- CBNumber:
- CB5471195
- Summenformel:
- C14H11F3N2O2.C7H17NO5
- Molgewicht:
- 491.46
- MOL-Datei:
- 42461-84-7.mol
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1-Desoxy-1-(methylamino)-D-glucitol-2-[2-methyl-3-(perfluormethyl)anilino]nicotinat Eigenschaften
- Schmelzpunkt:
- 136.6-137.4 °C
- alpha
- -9～-12゜(D/20℃)(c=12,CH3OH)
- storage temp.
- room temp
- L?slichkeit
- H2O: freely soluble
- Aggregatzustand
- solid
- Farbe
- off-white
- Wasserl?slichkeit
- soluble
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xi |
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| R-S?tze: |
36/37/38 |
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| S-S?tze: |
26-36 |
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| RIDADR |
UN 2811 6.1 / PGI |
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| WGK Germany |
3 |
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| RTECS-Nr. |
LZ4367000 |
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| HS Code |
29339900 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P271 |
Nur im Freien oder in gut belüfteten R?umen verwenden. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P302+P352 |
BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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1-Desoxy-1-(methylamino)-D-glucitol-2-[2-methyl-3-(perfluormethyl)anilino]nicotinat Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
White Solid
Verwenden
Flunixin meglumine has been used as a nonsteroidal anti-inflammatory drug standard in electrospray ionization mass spectrometry (LC-ESI/MS).
Definition
ChEBI: An organoammonium salt obtained by combining flunixin with one molar equivalent of 1-deoxy-1-(methylamino)-D-glucitol. A relatively potent non-narcotic, nonsteroidal analgesic with anti-inflammatory, anti-endotoxic and anti-pyretic propert
es; used in veterinary medicine for treatment of horses, cattle and pigs.
Allgemeine Beschreibung
Flunixin meglumine is a nonsteroidal anti-inflammatory drug and a potent cyclo-oxygenase (COX) inhibitor. It is commonly used as an analgesic and antipyretic in animals.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Synthese
Flunixin meglumine is prepared by the reaction of 1-deoxy-1-(methylamino)-D-glucitol and flunixin. The steps are as follows:
Reacting the flunixin with N-methylglucamine in isopropanol, the molar ratio of flunixin to N-methylglucamine is 2:1; fluorine Nisin has a mass ratio to isopropanol of 1:11; and simultaneously added maltodextrin; the molar ratio of the maltodextrin to 2-methyl-3-trifluoromethylaniline is 1:2.5; heating Reflux, filtration, cooling, stirring and crystallization, stirring is continued until the temperature of the system drops below 25 ° C, and the crystals are filtered with suction to obtain flunixin meglumine.
1-Desoxy-1-(methylamino)-D-glucitol-2-[2-methyl-3-(perfluormethyl)anilino]nicotinat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
1-Desoxy-1-(methylamino)-D-glucitol-2-[2-methyl-3-(perfluormethyl)anilino]nicotinat Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 492)Lieferanten
42461-84-7(1-Desoxy-1-(methylamino)-D-glucitol-2-[2-methyl-3-(perfluormethyl)anilino]nicotinat)Verwandte Suche:
- 2-[[2-methyl-3-(trifluoromethyl)phenyl]amino]-3-pyridinecarboxylate, 1-deoxy-1-(methylamino)-D-glucitol(1:1)
- Flunixin Solution, 100ppm
- Flunixin Meglumine injectable grade
- flunixinn-methylglucanine
- ino)-3-pyridinecarboxylate(salt)
- BANAMINE
- FLUNIXINE MEGLUMINE SALT
- FLUNIXIN MEGLUMINE SALT
- 1-deoxy-1-(methylamino)-d-glucitol 2-[2-methyl-3-(perfluoromethyl)anilino]nicotinate
- FLUNIXIN MEGLUMINE
- 2-[[2-METHYL-3-(TRIFLUOROMETHYL)PHENYL]AMINO]-3-PYRIDINECARBOXYLIC ACID MEGLUMINE SALT
- Flunmin Meglumine
- Finadyne
- D-Glucitol, 1-deoxy-1-(methylamino)-, 2-2-methyl-3-(trifluoromethyl)phenylamino-3-pyridinecarboxylate (salt)
- FLUNIXINMEGLUMINE,USP
- 2-[2-methyl-3-(trifluoromethyl)anilino]pyridine-3-carboxylic acid
- Flunixin meglumine,2-[[2-Methyl-3-(trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic acid meglumine salt, Banamine
- Flunixin Meglumine (300 mg)
- 2-(2-Methyl-3-trifluoroMethylanilino)nicotinic Acid N-Methyl-D-glucaMine Salt
- 2-[[2-Methyl-3-(trifluoroMethyl)phenyl]aMino]-3-pyridinecarboxylic Acid 1-Deoxy-1-(MethylaMino)-D-glucitol
- Equileve
- Flunixin N-MethylglucaMine
- IliuM Flunixil
- NIH 10250
- Cladomia bacillaris
- FLAVONE HIPPOPHAES
- Banamine, 2-[[2-Methyl-3-(trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic acid meglumine salt
- Flunixin meglumine, 98.5%
- 2-[2-methyl-3-(trifluoromethyl)anilino]-3-pyridinecarboxylic acid
- Flunixin meglumin in stock GMP Factory
- Flunixin meglumine for veterinary use
- Flunixin meglumine USP37 42461-84-7 Flunixin meglumin
- Flunixin meglumine 42461-84-7 USP37 Manufacturer High quality Best price In stock GMP factory Flunixin meglumin
- Flunixin meglumine CRS
- Flunixin Meglumine Standard
- fluixi egluie
- (2R,3R,4R,5S)-6-(Methylamino)hexane-1,2,3,4,5-pentaol 2-((2-methyl-3-(trifluoromethyl)phenyl)amino)nicotinate
- Flunixin meglumine USP/EP/BP
- Flunixin Meglumine (1274607)
- Flunixin Meglunine
- flunixin meglumin
- Flunixin meglumkine
- 1-deoxy-1-(methylamino)-d-glucito2-((2-methyl-3-(trifluoromethyl)phenyl)am
- lunixinmeglumine
- Flunixin Meglumine EP/USP
- Flucinib meglumine salt
- Flunisin meglumine
- D-Glucitol, 1-deoxy-1-(methylamino)-, 2-[[2-methyl-3-(trifluoromethyl)phenyl]amino]-3-pyridinecarboxylate (1:1)
- C13727000 Flunixin meglumine
- Flunixin meglumine, 10 mM in DMSO
- 42461-84-7
- 42451-84-7
- C14H11F3N2O2C7H17NO5
- C14H11F3N2O2C7H17NO
- Enzymes, Inhibitors, and Substrates
- Enzyme Inhibitors
- Enzyme Inhibitors by Enzyme
- Cyclooxygenase
