Purin-6(1H)-on
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Purin-6(1H)-on Eigenschaften
- Schmelzpunkt:
- >300 °C (lit.)
- Siedepunkt:
- 250.36°C (rough estimate)
- Dichte
- 1.4295 (rough estimate)
- Brechungsindex
- 1.8500 (estimate)
- storage temp.
- 2-8°C
- L?slichkeit
- 1 M NaOH: 25 mg/mL
- Aggregatzustand
- powder
- pka
- 8.7(at 25℃)
- Farbe
- Colorless to yellow to brown, darken on storage with no loss of purity
- Geruch (Odor)
- Odorless
- Wasserl?slichkeit
- practically insoluble
- Merck
- 14,4869
- BRN
- 5811
- InChIKey
- FDGQSTZJBFJUBT-UHFFFAOYSA-N
- LogP
- -0.910 (est)
- CAS Datenbank
- 68-94-0(CAS DataBase Reference)
- NIST chemische Informationen
- Hypoxanthine(68-94-0)
- EPA chemische Informationen
- Hypoxanthine (68-94-0)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher | Xn | ||
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R-S?tze: | 36/37/38-22-40 | ||
S-S?tze: | 22-24/25-37/39-26-36 | ||
WGK Germany | 3 | ||
RTECS-Nr. | UP0791000 | ||
Hazard Note | Harmful | ||
TSCA | Yes | ||
HS Code | 29335990 | ||
Toxizit?t | LD50 intraperitoneal in mouse: 750mg/kg |
Bildanzeige (GHS) | ||||||||||||||||||||||||||||||||||||
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Sicherheit |
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Purin-6(1H)-on Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.R22:Gesundheitssch?dlich beim Verschlucken.
R40:Verdacht auf krebserzeugende Wirkung.
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.S24/25:Berührung mit den Augen und der Haut vermeiden.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
Hypoxanthine is a naturally occurring purine derivative and intermediate in the synthesis of uric acid. It is elevated in the spinal fluid of patients with Lesch-Nyhan syndrome, a metabolic disorder whose symptoms include cerebral palsy, cognitive deficits, motor dysfunction, self-mutilation, and hyperuricemia. Injection of hypoxanthine (10 μM) increases succinate dehydrogenase and complex II activities and decreases cytochrome c oxidase activity, resulting in neuroenergetic impairment, ATP depletion, and cellular apoptosis in rat striatum. It is also used to induce hyperuricemia in mice for use in the development of hypouricemic agents.Chemische Eigenschaften
White to off-white powderVerwenden
A naturally occurring purine derivative. Pharmaceuticals, Intermediates & Fine ChemicalsDefinition
ChEBI: A purine nucleobase that consists of purine bearing an oxo substituent at position 6.Allgemeine Beschreibung
Hypoxanthine (6-hydroxypurine), a purine derivative is a naturally occurring compound. It is the deaminated form of adenine and a breakdown product of adenosine monophosphate (AMP).Sicherheitsprofil
Moderately toxic by intraperitoneal route. An experimental teratogen. When heated to decomposition it emits toxic fumes of Noxl?uterung methode
Crystallise it from hot water and dry it at 105o. [Beilstein 26 II 252, 26 III/IV 2081.]Purin-6(1H)-on Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
6-Dimethylaminopurin
6-N-HEPTYLMERCAPTOPURINE
Adenin
Mercaptopurin
N-Hexyl-1H-adenin
6-Ethoxy-1H-purin
1H-Purin-6-carbonitril
6-benzylaminopurine
6-ETHYLMERCAPTOPURINE
Aciclovir
6-Brom-1H-purin
N6-CYCLOHEXYLADENOSINE
6-Mercaptopurine monohydrate
N-(2-Hydroxyethyl)adenosine
6-Butoxy-1H-purin
Purin
Benzyl(purin-6-yl)amin
6-Iodpurin
6-benzylaminopurine hydrochloride
Purin-6(1H)-on Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 785)Lieferanten
Firmenname | Telefon | Land | Produktkatalog | Edge Rate | |
---|---|---|---|---|---|
Hebei Weibang Biotechnology Co., Ltd | +8615531157085 |
abby@weibangbio.com | China | 8806 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 |
sales@hbmojin.com | China | 12834 | 58 |
airuikechemical co., ltd. | +86-18353166132 +86-18353166132 |
sales02@airuikechemical.com | China | 983 | 58 |
Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618092446649 |
sarah@tnjone.com | China | 1143 | 58 |
Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 |
admin@zlchemi.com | China | 3002 | 58 |
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | +8615350851019 |
admin@86-ss.com | China | 1001 | 58 |
Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 |
sales@capot.com | China | 29791 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 18751 | 58 |
Shanghai Bojing Chemical Co.,Ltd. | +86-86-02137122233 +8613795318958 |
bj1@bj-chem.com | China | 299 | 55 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21634 | 55 |
68-94-0(Purin-6(1H)-on)Verwandte Suche:
6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purin-2-amin
5-Chlor-1-methyl-1H-imidazol
Inosin 5'-monophosphatdinatriumsalzhydrat
Isoguanin
2-[(2-Acetamido-6,9-dihydro-6-oxo-1H-purin-9-yl]methoxy]ethylacetat
2-Amino-1,7-dihydro-6H-purin-6-onmonohydrochlorid
Guanin
8-Bromguanosin
Purin-2(3H),6(1H)-dion
Bis(2-amino-1,7-dihydro-6H-purin-6-on)sulfat
1,2,3,7-Tetrahydro-2-thioxo-6H-purin-6-on
Inosin
Guanosin, N-(1-Oxobutyl)-, zyklisches 3',5'-(Hydrogen-phosphat)-2'-butanoat, Mononatriumsalz
2',3'-Isopropylideninosin
3'-Guanylsure, Dinatriumsalz
Purin-6(1H)-on
5'-O-[Bis(4-methoxyphenyl)benzyl]-2'-desoxy-N-(2-methyl-1-oxopropyl)guanosin
Guanosin, zyklisches 3',5'-(Hydrogen-phosphat), Mononatriumsalz
- HYPOXANTHINE ANHYDROUS
- Hypoxanthinee
- HYPOXANTHINE(RG)
- 6-HYDROXYPURINE(HYPOXANTHINE)
- purine-6(1H)-one
- Hypexanthine
- 6-oxypurine
- HYPOXANTHINE extrapure
- HYPOXANTHINE (Hyp)
- Didanosine Related CoMpound A
- Didanosine Related Compound A (25 mg) (Hypoxanthine)
- Hypoxanthine, 99.5% 25GR
- Hypoxanthine, 99.5% 5GR
- 1,9-Dihydro-
- Hypoxanthine API
- Hypoxanthine ,98%
- 6(1H)-PURINONE
- HYPOXANTHINE CELL CULTURE TESTED
- HYPOXANTHINE 99%
- HypoxanthineForBiochemistry
- HypoxanthineForBiochemistry99%
- HYPOXANTHINE FOR BIOCHEMISTRY 99%
- 6H-Purin-6-one, 1,7-dihydro- (9CI)
- 1,7-dihydro-6h-purin-6-on
- 1,7-Dihydro-6H-purine-6-one
- AKOS BBS-00002144
- 3H-Purin-6-ol
- 4-Hydroxy-1H-purine
- 6-Hydropurine
- 6-Hydroxy-1H-purine
- 6-Oxopurine
- 7H-Purin-6-ol
- 9H-Purin-6(1H)-one
- 1H-Purin-6(9H)-one
- Hypoxanthine Vetec(TM) reagent grade, 98%
- 1H-Purin-6(7H)-one
- Hypoxanthine, Animal-Free
- Hypoxsanthine (1,7-Dihydro-6H-purin-6-one)
- hypoxanthineenol
- Hypoxathine
- Purin-6(3H)-one
- Purine-6-ol
- Sarkine
- Purin-6(1H)-one
- PURIN-6-OL
- SARCINE
- SARKIN
- TTGGTTGGGTGGTHGGTGTTGGGG
- TIMTEC-BB SBB004203
- IFLAB-BB F1386-0269
- LABOTEST-BB LT00440805
- 6-HYDROXYPURINE
- Mercaptopurine EP Impurity A
- Didanosin Related Compound A
- Didanosine Impurity 1(Didanosine EP Impurity A)
- Mercaptopurine Impurity 1(Mercaptopurine EP Impurity A)
- Hypoxanthine - CAS 68-94-0 - Calbiochem
- Didanosine Impurity Ⅰ:6-Hydroxypurine