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NSC5844

NSC5844 Struktur
140926-75-6
CAS-Nr.
140926-75-6
Englisch Name:
NSC5844
Synonyma:
RE640;RE 640;RE-640;NSC5844;NSC5844 (RE640);NSC 5844; NSC-5844; RE 640; RE-640; RE640;N,N'-bis(7-chloroquinolin-4-yl)ethane-1,2-diamine;1,2-Ethanediamine, N1,N2-bis(7-chloro-4-quinolinyl)-;NSC 5844,RE640,NSC5844,inhibit,Inhibitor,RE 640,Parasite,NSC-5844
CBNumber:
CB53121123
Summenformel:
C20H16Cl2N4
Molgewicht:
383.27
MOL-Datei:
140926-75-6.mol

NSC5844 Eigenschaften

Siedepunkt:
632.6±55.0 °C(Predicted)
Dichte
1.431±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
DMF: 0.33 mg/ml; DMSO: 0.25 mg/ml; Ethanol: slightly soluble
Aggregatzustand
A crystalline solid
pka
6.61±0.50(Predicted)
Farbe
White to off-white

Sicherheit

NSC5844 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

NSC 5844 is a bis-quinoline with diverse biological activities. It inhibits the growth of P. falciparum strains that are sensitive (D-6) and resistant (W-2) to chloroquine in vitro (IC50s = 17 and 27 nM, respectively) but lacks activity against P. berghei in vivo. NSC 5844 inhibits the growth of MDA-MB-468 and MCF-7 breast cancer cells with GI50 values of 7.35 and 14.80 μM, respectively. It also inhibits 24% of botulinum neurotoxin serotype A light chain (BoNT/A LC) metalloprotease activity at a concentration of 20 μM.

NSC5844 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


NSC5844 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 71)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32820 60
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32038 58
InvivoChem
+1-708-310-1919 +1-13798911105
sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc.

support@targetmol.com United States 38463 58
ShenZhen Trendseen Biological Technology Co.,Ltd.
13417589054
trendseenbio@gmail.com China 11681 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652
info@fdachem.com China 20288 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 57505 58
Wuhan Jingkang en Biomedical Technology Co., Ltd
+8613720134139
orders@jknbiochem.com China 5221 58
SHANGHAI KEAN TECHNOLOGY CO., LTD.
+8613817748580
cooperation@kean-chem.com China 40066 58
Amadis Chemical Company Limited
571-89925085
sales@amadischem.com China 131957 58

140926-75-6()Verwandte Suche:


  • NSC5844
  • N,N'-bis(7-chloroquinolin-4-yl)ethane-1,2-diamine
  • 1,2-Ethanediamine, N1,N2-bis(7-chloro-4-quinolinyl)-
  • RE-640
  • RE640
  • RE 640
  • NSC 5844; NSC-5844; RE 640; RE-640; RE640
  • NSC5844 (RE640)
  • NSC 5844,RE640,NSC5844,inhibit,Inhibitor,RE 640,Parasite,NSC-5844
  • 140926-75-6
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