Antu (ISO)
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Antu (ISO) Eigenschaften
- Schmelzpunkt:
- 193 °C
- Siedepunkt:
- 377.6±25.0 °C(Predicted)
- Dichte
- 1.333
- Brechungsindex
- 1.5500 (estimate)
- storage temp.
- Poison room
- L?slichkeit
- 4.3 and 86 g/L in acetone and triethylene glycol, respectively (Windholz et al., 1983)
- pka
- 13.12±0.70(Predicted)
- Aggregatzustand
- Crystals or Crystalline Powder
- Farbe
- Grayish to beige-brown
- Geruch (Odor)
- bitter taste
- Wasserl?slichkeit
- 600 mg/L at 20 °C (quoted, Windholz et al., 1983)
- Merck
- 14,722
- BRN
- 778118
- Expositionsgrenzwerte
- NIOSH REL: TWA 0.3 mg/m3, IDLH 100 mg/m3; OSHA PEL: TWA 0.3 mg/m3
- CAS Datenbank
- 86-88-4(CAS DataBase Reference)
- IARC
- 3 (Vol. 30, Sup 7) 1987
- EPA chemische Informationen
- .alpha.-Naphthylthiourea (86-88-4)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher | T+ | ||
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R-S?tze: | 28-40 | ||
S-S?tze: | 28-36/37-45-25-23 | ||
RIDADR | 1651 | ||
OEB | C | ||
OEL | TWA: 0.3 mg/m3 | ||
WGK Germany | 2 | ||
RTECS-Nr. | YT9275000 | ||
TSCA | Yes | ||
HazardClass | 6.1 | ||
PackingGroup | I | ||
HS Code | 29309090 | ||
Giftige Stoffe Daten | 86-88-4(Hazardous Substances Data) | ||
Toxizit?t | Acute oral LD50 for Norwegian rats 6–8 mg/kg (Hartley and Kidd, 1987). | ||
IDLA | 100 mg/m3 |
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Alarmwort | Achtung | |||||||||||||||||||||
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Sicherheit |
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Antu (ISO) Chemische Eigenschaften,Einsatz,Produktion Methoden
ERSCHEINUNGSBILD
WEISSES, GERUCHLOSES, KRISTALLINES PULVER.CHEMISCHE GEFAHREN
Zersetzung beim Erhitzen unter Bildung giftiger Gaseund giftiger Rauche mit Stickstoffoxiden, Schwefeloxidenund Kohlenmonoxid. Reagiert mit starken Oxidationsmitteln unter Feuer- und Explosionsgefahr.ARBEITSPLATZGRENZWERTE
TLV: 0,3 mg/m?(als TWA); Krebskategorie A4 (nicht klassifizierbar als krebserzeugend für den Menschen); (ACGIH 2005).MAK: 0,3 mg/m?(Einatembare Fraktion); Spitzenbegrenzung: überschreitungsfaktor II(2); (DFG 2005).
AUFNAHMEWEGE
Aufnahme in den K?rper durch Inhalation des Aerosols, über die Haut und durch Verschlucken.INHALATIONSGEFAHREN
Verdampfung bei 20°C vernachl?ssigbar; eine gesundheitssch?dliche Partikelkonzentration in der Luft kann jedoch schnell erreicht werden.WIRKUNGEN BEI KURZZEITEXPOSITION
WIRKUNGEN BEI KURZZEITEXPOSITION:Exposition gegenüber der Substanz kann zu Lungen?dem führen. ?rztliche Beobachtung notwendig.
LECKAGE
Verschüttetes Material in Beh?ltern sammeln; falls erforderlich durch Anfeuchten Staubentwicklung verhindern. Reste sorgf?ltig sammeln. An sicheren Ort bringen. Pers?nliche Schutzausrüstung: Atemschutzger?t, P3-Filter für giftige Partikel.R-S?tze Betriebsanweisung:
R28:Sehr giftig beim Verschlucken.R40:Verdacht auf krebserzeugende Wirkung.
S-S?tze Betriebsanweisung:
S28:Bei Berührung mit der Haut sofort abwaschen mit viel . . . (vom Hersteller anzugeben).S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
S25:Berührung mit den Augen vermeiden.
S23:Gas/Rauch/Dampf/Aerosol nicht einatmen(geeignete Bezeichnung(en) vom Hersteller anzugeben).
Beschreibung
a-Naphthylthiourea (ANTU; also called DIRAX) is toxic by inhalation, ingestion, or skin contact. Due to its very narrow spectrum of activity, production was discontinued a long time ago. Exposure to ANTU causes pulmonary edema; therefore, it is often used as an experimental pneumotoxin. ANTU is a graycolored, prism-shaped, odorless powder with a bitter taste. It has a molecular weight of 202.28 and melting point of 200 ℃ and does not ignite readily. However, on interaction with potential oxidizing agents, it may cause fire and explosions, which can lead to hazardous decomposition products such as sulfur dioxide, nitrogen dioxide, and carbon monoxide. The structure of ANTU contains the naphthalene chromophore, which absorbs UV light at ~311 nm. This suggests that ANTU can undergo photolysis.Chemische Eigenschaften
greyish to beige-brown crystals or cryst. powderPhysikalische Eigenschaften
Colorless crystals when pure. Technical product is grayish-blue. Odorless solid. Bitter taste.Verwenden
Rodenticide. Specific control for the adult Norway rat; less toxic to other rat species.Allgemeine Beschreibung
White crystal or powder; technical product is gray powder. Has no odor but a bitter taste. Used primarily as a rodenticide for control of adult Norway rats. Not produced commercially in the U.S.Air & Water Reaktionen
Slightly soluble in water.Reaktivit?t anzeigen
1-(1-NAPHTHYL)-2-THIOUREA is incompatible with the following: Strong oxidizers, silver nitrate .Hazard
Toxic by ingestionHealth Hazard
Moderately toxic: probable oral lethal dose (human) 0.5-5 gm/kg, or between 1 ounce and 1 pint (or l lb.) for 150 lb. person. Chronic sublethal exposure may cause antithyroid activity. Can produce hyperglycemia of three times normal in three hours. People with chronic respiratory disease or liver disease may be especially at risk.Brandgefahr
Emits sulfur dioxide, oxides of nitrogen, and carbon monoxide fumes upon decomposition. 1-(1-NAPHTHYL)-2-THIOUREA reacts with silver nitrate and strong oxidizers. Avoid decomposing heat.Sicherheitsprofil
Poison by ingestion and intraperitoneal routes. Moderately toxic to humans by an unspecified route. Questionable carcinogen with experimental tumorigenic data. Mutagenic data. A rodenticide used extensively. Death is caused by pulmonary edema. Chronic toxicity has been known to cause dermatitis and a decrease in the white blood cells. When heated to decomposition it emits toxic fumes of NOx and SOx.m?gliche Exposition
ANTU or its formulations are used as a rodenticide.Carcinogenicity
ANTU was not carcinogenic in rodent feeding studies.4 Cases of bladder tumors among rat catchers exposed to ANTU have been attributed to b-naphthylamine, a manufacturing impurity of ANTU. In bacterial assays ANTU induced mutations.Environmental Fate
Chemical/Physical. The hydrolysis rate constant for ANTU at pH 7 and 25°C was determined to be 8 × 10–5/hour, resulting in a half-life of 361 days (Ellington et al., 1988)Emits very toxic fumes of nitrogen and sulfur oxides when heated to decomposition (Lewis, 1990)
Lager
α-Naphthalene thiourea should be kept stored in a tightly closed container in a locked poison room, in a cool, dry, well-ventilated area away from incompatible substances.Versand/Shipping
UN1651 Naphthylthiourea, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.l?uterung methode
Crystallise ANTU from EtOH. [Beilstein 12 III 2941, 12 IV 3086.]Inkompatibilit?ten
Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, silver nitrate.Waste disposal
Incinerate in a furnace equipped with an alkaline scrubber. Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal.Vorsichtsma?nahmen
Workers should use/handle α-naphthalene thiourea with adequate ventilation. During use, dust generation and accumulation should be minimum, and avoid contact with the eyes, skin, and clothing.Antu (ISO) Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Natriumthiocyanat
2-AMINONAPHTHALENE HYDROCHLORIDE
Ammoniumthiocyanat
1-Naphthylamin
Kaliumthiocyanat
Downstream Produkte
Antu (ISO) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 107)Lieferanten
Firmenname | Telefon | Land | Produktkatalog | Edge Rate | |
---|---|---|---|---|---|
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 |
admin@nexconn.com | China | 10311 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28172 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22963 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49374 | 58 |
Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 |
1026@dideu.com | China | 8670 | 58 |
SUZHOU SENFEIDA CHEMICAL CO.,LTD | +86-0512-83500002 +8615195660023 |
sales@senfeida.com | China | 23046 | 58 |
XIAMEN AMITY INDUSTRY AND TRADE CO., LTD. | +8618950047208 |
ellena@amitychem.com | China | 43416 | 58 |
Amadis Chemical Company Limited | 571-89925085 |
sales@amadischem.com | China | 131957 | 58 |
ORGANICA Feinchemie GmbH | +49 3494636389 |
info@organica.de | Germany | 598 | 65 |
Mainchem Co., Ltd. | +86-0592-6210733 |
sale@mainchem.com | China | 32343 | 55 |
86-88-4(Antu (ISO))Verwandte Suche:
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- antu (bsi,iso,jmaf)
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