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Simfibrat

simfibrate Struktur
14929-11-4
CAS-Nr.
14929-11-4
Bezeichnung:
Simfibrat
Englisch Name:
simfibrate
Synonyma:
CLY-503;Sinfibrate;simfibrate;Cholesolvin;simfibrate USP/EP/BP;1,3-Propanediol bis[2-(4-chlorophenoxy)-2-methylpropionate];Propane-1,3-diyl bis(2-(4-chlorophenoxy)-2-methylpropanoate);Bis[2-(4-chlorophenoxy)-2-methylpropanoic acid] 1,3-propanediyl;Propanoic acid, 2-(4-chlorophenoxy)-2-methyl-, 1,1'-(1,3-propanediyl) ester;3-[2-(4-chlorophenoxy)-2-methylpropanoyl]oxypropyl 2-(4-chlorophenoxy)-2-methylpropanoate
CBNumber:
CB4875031
Summenformel:
C23H26Cl2O6
Molgewicht:
469.35
MOL-Datei:
14929-11-4.mol

Simfibrat Eigenschaften

Schmelzpunkt:
51-53°
Siedepunkt:
bp0.03 197-200°; bp0.15 220-230°
Dichte
1.2623 (estimate)

Sicherheit

Toxizit?t LD50 in mice, rats (g/kg): 3.3-3.5; 7.3-8.0 orally (Nakanishi, J. Pharm. Soc. Japan)

Simfibrat Chemische Eigenschaften,Einsatz,Produktion Methoden

Originator

Cholesorbin,Takeda,Japan,1971

Manufacturing Process

A mixture of 22 grams of α-(p-chlorophenoxy)isobutyric acid, 3.8 grams of 1,3-propanediol, 0.5 gram of p-toluenesulfonic acid and 150 ml of xylene was refluxed. When the theoretically calculated amount of water had been removed, the xylene solution was washed with dilute aqueous sodium bicarbonate and then the xylene was distilled off. The residue was distilled under reduced pressure to give 11 grams (47% yield) of 1,3-propanediol bis[α-(p-chlorophenoxy)isobutyrate] boiling at 197° to 200°C/0.03 mm Hg.

Therapeutic Function

Antihyperlipidemic

Simfibrat Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Simfibrat Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 18)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shaanxi Dideu Medichem Co. Ltd
+86-029-89586680 +86-18192503167
1026@dideu.com China 7724 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207
sales@molcore.com China 49734 58
TargetMol Chemicals Inc.

support@targetmol.com United States 38631 58
TargetMol Chemicals Inc.
+8613564774135
zijue.cai@tsbiochem.com United States 19885 58
LGM Pharma 1-(800)-881-8210
inquiries@lgmpharma.com United States 2123 70
Aikon International Limited 025-58851090 13611564524
lwan@aikonchem.com China 15951 58
TargetMol Chemicals Inc. 4008200310
marketing@tsbiochem.com China 24644 58
Shaanxi Dideu Newmaterial Co., Ltd. 029-87576359 15353716720
1039@dideu.com China 10009 58

14929-11-4(Simfibrat)Verwandte Suche:


  • simfibrate
  • 1,3-Propanediol bis[2-(4-chlorophenoxy)-2-methylpropionate]
  • Bis[2-(4-chlorophenoxy)-2-methylpropanoic acid] 1,3-propanediyl
  • Cholesolvin
  • CLY-503
  • Sinfibrate
  • simfibrate USP/EP/BP
  • Propanoic acid, 2-(4-chlorophenoxy)-2-methyl-, 1,1'-(1,3-propanediyl) ester
  • Propane-1,3-diyl bis(2-(4-chlorophenoxy)-2-methylpropanoate)
  • 3-[2-(4-chlorophenoxy)-2-methylpropanoyl]oxypropyl 2-(4-chlorophenoxy)-2-methylpropanoate
  • 14929-11-4
  • C23H26Cl2O6
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