3,4',5,7-Tetrahydroxyflavon
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3,4',5,7-Tetrahydroxyflavon Eigenschaften
- Schmelzpunkt:
- 276°C
- Siedepunkt:
- 348.61°C (rough estimate)
- Dichte
- 1.2981 (rough estimate)
- Brechungsindex
- 1.4413 (estimate)
- storage temp.
- 2-8°C
- L?slichkeit
- ethanol: 20 mg/mL
- pka
- 6.34±0.40(Predicted)
- Aggregatzustand
- powder
- Colour Index
- 75640
- Farbe
- yellow
- Merck
- 14,5274
- BRN
- 304401
- Stabilit?t:
- Unstable in Solution
- InChIKey
- IYRMWMYZSQPJKC-UHFFFAOYSA-N
- LogP
- 2.685 (est)
- CAS Datenbank
- 520-18-3(CAS DataBase Reference)
- IARC
- 3 (Vol. 31, Sup 7) 1987
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher | Xi,T | ||
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R-S?tze: | 36/37/38-68-25 | ||
S-S?tze: | 26-36-45-36/37-36/37/38-22 | ||
RIDADR | 2811 | ||
WGK Germany | - | ||
RTECS-Nr. | LK9275200 | ||
F | 8-10-23 | ||
HS Code | 29329990 | ||
Giftige Stoffe Daten | 520-18-3(Hazardous Substances Data) |
Bildanzeige (GHS) | |||||||||||||||
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Alarmwort | Warnung | ||||||||||||||
Gefahrenhinweise |
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Sicherheit |
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3,4',5,7-Tetrahydroxyflavon Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
Yellow SolidVerwenden
Kaempferol, is used as an inhibitor of Fatty Acid Synthase, Cox-1 activity, and Topo I. It also Induces caspase-9-mediated apoptosis in a variety of cancer cell lines via downregulation of polo-like kinase 1 (PLK1) expression. Exhibits antioxidant activity and attenuates osteoclastic bone reabsorption in vitro. Also blocks EGF-induced histone H3Ser10 phosphorylation in mouse epidermal JB6 C141 cells.Allgemeine Beschreibung
Kaempferol is a polyphenolic antioxidant abundantly present in vegetables and fruits. It has a diphenylpropane structure. In many plants, it is present as a glycosidic form namely, kaempferol-3-O-glucoside.Biologische Aktivit?t
Naturally occurring flavonoid found in Gingko biloba and red wines that activates the mitochondrial Ca 2+ uniporter (EC 50 = 7 μ M). Induces caspase-9-mediated apoptosis in a variety of cancer cell lines via downregulation of polo-like kinase 1 (PLK1) expression. Exhibits antioxidant activity and attenuates osteoclastic bone reabsorption in vitro .Anticancer Research
Kaempferol is one of the secondary metabolites found in some plants, plant-derivedfoods, and traditional medicines. It is a flavonoid compound obtained from someedible plants including grapes, tea, strawberries, broccoli, tomato, cabbage, leek,kale, endive, and beans. It inhibits growth and migration of pancreatic cancer cellsby acting on proto-oncogene tyrosine kinase (Src), ERK1/2, and AKT pathways(Singh et al. 2016a). It is being investigated in pancreatic and lung cancers toevaluate its antiangiogenic, anticancer, and radical scavenging activities. It showsmoderate cytostatic activity in PC3, HeLa, and K562 human cancer cells. It isidentified as aryl hydrocarbon receptor antagonist and acts against ABCG2 (ATP-bindingcassette subfamily G member 2)-mediated multidrug resistance bypreventing the ABCG2 upregulation in esophageal carcinoma. It induces theapoptosis of ovarian cancer cell by activating p53 in intrinsic pathway mechanism.It is an inhibitor of breast cancer resistance protein (BCRP), quinine reductase-2,and a substrate of BCRP (Calderon-Montano et al. 2011; Wang et al. 2012).3,4',5,7-Tetrahydroxyflavon Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
3,4',5,7-Tetrahydroxyflavon Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 592)Lieferanten
Firmenname | Telefon | Land | Produktkatalog | Edge Rate | |
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Shaanxi LonierHerb Bio Technology Co Ltd | +86-86-+86-86-029-87551862 +8617702909819 |
sales006@ingredients-lonier.com | China | 2608 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 |
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deasea125996@gmail.com | China | 2472 | 58 |
Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 |
lisa@kingfinertech.com | China | 3010 | 58 |
Wuhan Haorong Biotechnology Co.,ltd | +86-18565342920; +8618565342920 |
sales@chembj.net | China | 289 | 58 |
Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 |
qinhe02@xaltbio.com | China | 997 | 58 |
Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 |
admin@guyunchem.com | China | 615 | 58 |
Chongqing Zhihe Biopharmaceutical Co., Ltd. | +86-18580541567; +8618580541567 |
sales@zhswyy.com | China | 301 | 58 |
520-18-3(3,4',5,7-Tetrahydroxyflavon)Verwandte Suche:
3,5,7-Trihydroxy-2-(4-methoxyphenyl)-4-benzopyron
Flavon
7-Hydroxy-2-phenyl-4-benzopyron
Isoflavone
Hydroxy silicone oil
5,7-Dihydroxy-2-phenyl-4H-benzo[b]pyran-4-on
7-[[2-O-(6-Desoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-3,5-dihydroxy-2-(4-hydroxyphenyl)-4H-benzopyran-4-on
3,5-Dihydroxy-7-methoxy-2-(4-methoxyphenyl)-4-benzopyron
3,3',4,4',5',7-Hexahydro-2-phenyl-4H-chromen-4-on
3,5,7-Trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-benzopyron
3,3',4',5-Tetrahydroxy-7-methoxyflavon
Quercitrin
3-[(6-Desoxy-α-L-mannopyranosyl)oxy]-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-benzopyran-4-on
Rutosid
2-(3,4-Dihydroxyphenyl)-3-(β-D-galaktopyranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-on
3-[[6-O-(6-Desoxy-α-L-mannopyranosyl)-β-D-galaktopyranosyl]oxy]-7-[(6-desoxy-α-L-mannopyranosyl)oxy]-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-on
Quercetin
ISOFLAVONES
- 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4h-1-benzopyran-4-on
- 5,7,4’-trihydroxyflavonol
- c.i.75640
- indigoyellow
- kampherol
- nimbecetin
- pelargidenolon1497
- populnetin
- rhamnolutein
- rhamnolutin
- swartziol
- KAEMPFEROL
- 3,5,7,4'-TETRAHYDROXYFLAVONE
- 3,5,7-TRIHYDROXY-2-[4-HYDROXY-PHENYL]-4H-1-BENZOPYRAN-4-ONE
- 3,4',5,7-TETRAHYDTOXYFLAVONE
- ROBIGENIN
- 3,4'
- Kaempferol,3,4′,5,7-Tetrahydroxyflavone, 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, Robigenin
- KAEMPFEROL(RG)(PLEASECALL)
- KaeMpferol 
- 4β-Hydroxy Cholesterol-d4 (Major)
- NSC 407289
- NSC 656277
- Pelargidenon
- Trifolitin
- 4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-
- Kaempferol ,98%
- KAEMPFEROL(AMERICAN HERBAL PHARMACOPOEIA)
- KAEMPFERIDE(SH)
- Kaempferol 97 % pure
- KAEMPFEROL FROM GINKGO BILOBA LEAF 99+%(HPLC)
- KAEMPFEROL ROBIGENIN, 3,4',5,7-TETRAHYDRO-XY-FLAVONE
- Rhamnoluteun
- Robigenin/Kaempferol
- asurone
- KAEMPFEROL hplc
- 3,4',5,7-Tetrahydroxyflavone
- KAEMPFEROL ROBIGENIN
- KAEMPFEROL WITH HPLC
- 3,4μ,5,7-Tetrahydroxyflavone, 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, Robigenin
- 4',5,7-Trihydroxyflavonol
- Swartsiol
- 3.5,7,4'-tetrahydroxyflavone Swartziol Trifolitin Nimbecetin Populnetin
- Kaempferol, 98%, from Sophora japonica Linn.
- Nano Liposomal Kaempferol
- Kaempferol - CAS 520-18-3 - Calbiochem
- Kaempferol 520-18-3
- KaempferolHydrate>
- Kaempferol (3,4',5,7-Tetrahydroxyflavone)
- 3,4'',5,7-Tetrahydroxyflavone hydrate
- Locust horn extract/Resurrectionlily phenol
- Kaempferol USP/EP/BP
- aempherol
- Kaempferol /Kaempherol/Kempferol
- Kaempferol (Kempferol
- 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one[Robigenin
- Kaempferol (1354900)
- campherol