Medetomidine hydrochloride
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- CAS-Nr.
- 86347-15-1
- Englisch Name:
- Medetomidine hydrochloride
- Synonyma:
- MEDETOMIDINE HYDROCHLORIDE;edetomidine;(R)-4-[1-(2;medeomidine hcl;Metetomidine HCl;Medetomidine HCl Powder;Ethyl Acetate Impurity 85;Medetomidine HCl (MPV-785);Metoclopramide (metoclopramide);Medetomidine Hydrochloride Impurities
- CBNumber:
- CB52130917
- Summenformel:
- C13H17ClN2
- Molgewicht:
- 236.74
- MOL-Datei:
- 86347-15-1.mol
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Medetomidine hydrochloride Eigenschaften
- Schmelzpunkt:
- 164-166°C
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- L?slichkeit
- Acetonitrile (Slightly), Methanol (Slightly), Water (Slightly)
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- InChI
- InChI=1S/C13H16N2.ClH/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13;/h4-8,11H,1-3H3,(H,14,15);1H
- InChIKey
- VPNGEIHDPSLNMU-UHFFFAOYSA-N
- SMILES
- C(C1N=CNC=1)(C1C=CC=C(C)C=1C)C.Cl
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H317 |
Kann allergische Hautreaktionen verursachen. |
Sensibilisierung der Haut |
Kategorie 1A |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P261, P272, P280, P302+P352,P333+P313, P321, P363, P501 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
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| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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Medetomidine hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Medetomidine hydrochloride is a potent, highly selective α2-adrenoceptor agonist (Ki values are 1.08 and 1750 nM for α2- and α1-adrenoceptors respectively). It is an imidazole compound. Medetomidine hydrochloride shows greater selectivity over α1-adrenoceptors than clonidine and UK 14,304 (1620-, 220- and 300-fold respectively). In addition, it influences the adrenergic system by mimicking the action of adrenergic neurotransmitters.
Chemische Eigenschaften
White Solid
Pharmakokinetik
After intramuscular injection, medetomidine is rapidly and almost completely absorbed at the site of injection and its pharmacokinetics are very similar to that observed after intravenous injection. Maximum plasma concentrations are reached within 15 to 20 minutes. Estimated plasma half-life is 1.2 hours for dogs and 1.5 hours for cats. Medetomidine is mainly oxidised in the liver, while a small amount is methylated in the kidney. Metabolites are primarily excreted in urine.
Medetomidine hydrochloride Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Medetomidine hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 235)Lieferanten
86347-15-1()Verwandte Suche:
- (r)-4-[1-(2,3-dimethylphenyl)ethyl]-1h-imidazole hydrochloride
- 1H-Imidazole, 5-[1-(2,3-dimethylphenyl)ethyl]-, hydrochloride (1:1)
- 5-[1-(2,3-diMethylphenyl)ethyl]-1H-IMidazole hydrochloride
- edetomidine
- Medetomidine hydrochloride
(R)-4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride
- 5-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole monohydrochloride
- Metetomidine HCl
- (R)-4-[1-(2
- 3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride
- Medetomidine (hydrochloride) cas86347-15-1
- SIMS1031 Medetomidine HCl ---86347-15-1
25g
- 2-amino-5-(2-ethoxyanilino)-4-hydroxy-1H-pyrimidin-6-one
- Medetomidine Hcl Medetomidine Hydrochloride
- (R)-4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride USP/EP/BP
- Medetomidine Hydrochloride Impurities
- Metoclopramide (metoclopramide)
- medeomidine hcl
- Medetomidine HCl (MPV-785)
- MEDETOMIDINE HYDROCHLORIDE
- Medetomidine hydrochloride,anxiolysis,inhibit,sedation,Medetomidine,α2-adrenoceptor,MPV-785,peripheral nervous system,analgesia,MPV 785,central nervous system,Inhibitor,muscle relaxation,Beta Receptor,Adrenergic Receptor
- Medetomidine HCl Powder
- Ethyl Acetate Impurity 85
- 86347-15-1
- Aromatics
- Heterocycles
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Inhibitors
