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4-Iodo-2-(trifluoromethyl)pyridine

4-Iodo-2-(trifluoromethyl)pyridine Struktur
590371-73-6
CAS-Nr.
590371-73-6
Englisch Name:
4-Iodo-2-(trifluoromethyl)pyridine
Synonyma:
4-lodo-2-(trifluoromethyl)pyridine;2-(trifluoroMethyl)-4-iodopyridine;4-IODO-2-(TRIFLUOROMETHYL)PYRIDINE;4-IODE-2-(TRIFLUOROMETHYL)PYRIDINE;Pyridine,4-iodo-2-(trifluoromethyl)-;4-Iodo-2-(trifluoromethyl)pyridine97%;4-Iodo-2-(trifluoromethyl)pyridine 97%;4-Iodo-2-(trifluoromethyl)pyridine ISO 9001：2015 REACH;4-Iode-2-(trifluoromethyl)pyridine (not restricted/prohibited)(lab chemical)
CBNumber:
CB4722177
Summenformel:
C6H3F3IN
Molgewicht:
272.99
MOL-Datei:
590371-73-6.mol

4-Iodo-2-(trifluoromethyl)pyridine Eigenschaften

Schmelzpunkt:
24-26 °C
Siedepunkt:
206.2±35.0 °C(Predicted)
Dichte
1.974g/ml
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
Aggregatzustand
liquid
pka
-0.82±0.20(Predicted)
Farbe
Clear, colourless to pale yellow
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xi
HazardClass  IRRITANT
HS Code  2933399990
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H227 Combustible liquid Flammable liquids Category 4 Warnung P210, P280, P370+P378, P403+P235,P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

4-Iodo-2-(trifluoromethyl)pyridine Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

4-Iodo-2-(trifluoromethyl)pyridine is used as a reagent in the synthesis of aminoisoindoles as β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors which exhibit in vivo brain reduction of β-amyloid peptides.

Reaktivit?t anzeigen

4-Iodo-2-(trifluoromethyl)pyridine could be cleanly deprotonated by LIDA in tetrahydrofuran at –75 °C[1]. Trapping of the organometallic intermediates with dry ice followed by neutralization gave the 4-iodo-2-(trifluoromethyl)pyridine-3-carboxylic acid (16, 31%). a: LIDA in THF at –75 °C for 2 h; b: (1.) Excess solid carbon dioxide, (2.) Hydrochloric acid.4-Iodo-2-(trifluoromethyl)pyridine

4-Iodo-2-(trifluoromethyl)pyridine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

2-(Trifluoromethyl)isonicotinic acid 2-(Trifluoromethyl)pyridine-4-boronic acid

4-Iodo-2-(trifluoromethyl)pyridine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 107)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shanghai Boc Chemical Co., Ltd.
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ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32957 60
career henan chemical co 		+86-0371-86658258 +8613203830695
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Changzhou Ansciep Chemical Co., Ltd. 		+86 519 86305871
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Alchem Pharmtech,Inc. 		8485655694
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CONIER CHEM AND PHARMA LIMITED 		+8618523575427
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Fuxin Pharmaceutical 		+86-021-021-50872116 +8613122107989
 contact@fuxinpharm.com China 10032 58
Antai Fine Chemical Technology Co.,Limited 		18503026267
 info@antaichem.com CHINA 9636 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		+8613580539051
 joe@yuhengpharm.com CHINA 21142 58

590371-73-6()Verwandte Suche:

  • 4-Iodo-2-(trifluoromethyl)pyridine97%
  • 4-Iodo-2-(trifluoromethyl)pyridine 97%
  • 4-IODO-2-(TRIFLUOROMETHYL)PYRIDINE
  • 2-(trifluoroMethyl)-4-iodopyridine
  • Pyridine,4-iodo-2-(trifluoromethyl)-
  • 4-IODE-2-(TRIFLUOROMETHYL)PYRIDINE
  • 4-Iodo-2-(trifluoromethyl)pyridine ISO 9001：2015 REACH
  • 4-Iode-2-(trifluoromethyl)pyridine (not restricted/prohibited)(lab chemical)
  • 4-lodo-2-(trifluoromethyl)pyridine
  • 590371-73-6
  • 1250277-69-2
  • Pyridine
  • Pyridine series
  • Halides
  • Pyridines
  • Heterocycle
  • Fluorine series
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