2,4-Dichlorphenol Chemische Eigenschaften,Einsatz,Produktion Methoden
ERSCHEINUNGSBILD
FARBLOSE KRISTALLE MIT CHARAKTERISTISCHEM GERUCH.
PHYSIKALISCHE GEFAHREN
Die D?mpfe sind schwerer als Luft.
CHEMISCHE GEFAHREN
Beim Verbrennen Bildung ?tzender Gase (Chlorwasserstoff). Beim Erhitzen bilden sich giftige Rauche. Reagiert sehr heftig mit starken Oxidationsmitteln.
ARBEITSPLATZGRENZWERTE
TLV nicht festgelegt (ACGIH 2005).
MAK nicht festgelegt (DFG 2005).
AUFNAHMEWEGE
Aufnahme in den K?rper durch Inhalation des Aerosols, über die Haut und durch Verschlucken.
INHALATIONSGEFAHREN
Nur ungenügende Angaben vorhanden über die Geschwindigkeit, mit der eine gesundheitssch?dliche Konzentration in der Luft beim Verdampfen bei 20°C erreicht wird.
WIRKUNGEN BEI KURZZEITEXPOSITION
WIRKUNGEN BEI KURZZEITEXPOSITION: ?tzend. Die Substanz ver?tzt die Augen, die Haut und die Atemwege. ?tzend beim Verschlucken. Exposition in hohen Konzentrationen kann zum Tod führen. Exposition gegenüber kleinen Mengen der geschmolzenen oder flüssigen Form der Substanz kann zu erheblicher Hautresorption und schnellem Tod führen.
LECKAGE
Verschüttetes Material in Beh?ltern sammeln; falls erforderlich durch Anfeuchten Staubentwicklung verhindern. NICHT in die Umwelt gelangen lassen. Pers?nliche Schutzausrüstung: Vollschutzanzug mit umgebungsluftunabh?ngigem Atemschutzger?t.
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.
R24:Giftig bei Berührung mit der Haut.
R34:Verursacht Ver?tzungen.
R51/53:Giftig für Wasserorganismen, kann in Gew?ssern l?ngerfristig sch?dliche Wirkungen haben.
R39/23/24/25:Giftig: ernste Gefahr irreversiblen Schadens durch Einatmen, Berührung mit der Haut und durch Verschlucken.
R23/24/25:Giftig beim Einatmen, Verschlucken und Berührung mit der Haut.
R11:Leichtentzündlich.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
S61:Freisetzung in die Umwelt vermeiden. Besondere Anweisungen einholen/Sicherheitsdatenblatt zu Rate ziehen.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S16:Von Zündquellen fernhalten - Nicht rauchen.
Chemische Eigenschaften
white to beige crystalline solid
Physikalische Eigenschaften
Colorless to yellow crystals with a sweet, musty, or medicinal odor. At 40 °C, the average odor
threshold concentration and the lowest concentration at which an odor was detected were 29 and
5.4 μg/L, respectively. Similarly, at 25 °C, the average taste threshold concentration and the
lowest concentration at which a taste was detected were 2.5 and 0.98 μg/L, respectively (Young et
al., 1996).
Verwenden
2,4-Dichlorophenol is a chlorinated derivative of phenol and is used as an intermediate for the preparation of herbicide 2,4-dichlorophenoxyacetic acid (D435680).
Definition
ChEBI: A dichlorophenol that is phenol carrying chloro substituents at positions 2 and 4.
Allgemeine Beschreibung
Colorless crystalline solid with a medicinal odor. Melting point 45°C. Sinks in water. Strong irritant to tissues; toxic by ingestion.
Air & Water Reaktionen
Insoluble in water.
Reaktivit?t anzeigen
2,4-Dichlorophenol can react vigorously with oxidizing agents. Can also react with acids or acid fumes. Incompatible with acid chlorides and acid anhydrides.
Health Hazard
Tremors, convulsions, shortness of breath, inhibition of respiratory system.
Sicherheitsprofil
Suspected carcinogen
with experimental carcinogenic and
teratogenic data. Poison by intraperitoneal
route. Moderately toxic by ingestion and
subcutaneous routes. An experimental
teratogen. Mutation data reported.
Combustible when exposed to heat or
flame. Can react vigorously with oxidizing
materials. To fight fre, use alcohol foam,
foam, CO2, dry chemical. When heated to
decomposition, or on contact with acid or
acid fumes, it emits hghly toxic fumes of
Cl-. See also CHLOROPHENOLS.
m?gliche Exposition
2,4-Dichlorophenol is a commercially
produced substituted phenol used in the manufacture
of industrial and agricultural products; in synthesis of
pharmaceuticals. As an intermediate in the chemical industry, 2,4-DCP is utilized as the feedstock for the manufacture of 2,4-dichlorophenoxyacetic acid (2,4-D), and 2,4-D
derivatives (germicides, soil sterilants, etc.); certain methyl
compounds used in mothproofing, antiseptics and seed
disinfectants. 2,4-DCP is also reacted with benzene sulfonyl
chloride to produce miticides or further chlorinated to
pentachlorophenol, a wood preservative. It is thus a widely
used pesticide intermediate. The only group expected to be
at risk for high exposure to 2,4-DCP is industrial workers
involved in the manufacturing or handling of 2,4-DCP
and 2,4-D
Carcinogenicity
In mammalian cells in vitro 2,4-DCP produced
chromosomal aberrations and induced
unscheduled DNA synthesis; it was negative
for sister chromatid exchange in vivo and was
mostly negative in bacterial assays.
Oral exposure of pregnant rats to
750mg/kg/day for 10 gestational days induced
slightly decreased fetal weight, delayed ossification
of sternal and vertebral arches, and some
early embryonic deaths.10 Maternal deaths also
occurred at this dose, indicating that 2,4-DCP
was not selectively toxic to embryos or fetuses.
No effects were noted in dams or offspring
exposed at 375mg/kg/day.
A threshold limit value (TLV) has not been
established for 2,4-dichlorophenol.
Versand/Shipping
UN2020 Chlorophenols, solid, Hazard Class:
6.1; Labels: 6.1-Poisonous materials
l?uterung methode
Crystallise it from pet ether (b 30-40o). Purify it also by repeated zone melting, using a P2O5 guard tube to exclude moisture. It is very hygroscopic when dry. [Beilstein 6 IV 885.]
Inkompatibilit?ten
Incompatible with oxidizers (chlorates,
nitrates, peroxides, permanganates, perchlorates, chlorine,
bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases,
strong acids, oxoacids, and epoxides. Contact with acids or
acid fumes causes decomposition releasing poisonous
chlorine gas. Incompatible with caustics, acid anhydrides;
acid chlorides. Quickly corrodes aluminum; slowly
corrodes zinc, tin, brass, bronze, copper and its alloys. May
accumulate static electrical charges, and may cause ignition
of its vapors.
Waste disposal
Dissolve in a combustible
solvent and incinerate in a furnace equipped with afterburner and scrubber. In accordance with 40CFR165,
follow recommendations for the disposal of pesticides and
pesticide containers. Must be disposed properly by following package label directions or by contacting your local or
federal environmental control agency, or by contacting
your regional EPA office. Consult with environmental
regulatory agencies for guidance on acceptable disposal
practices. Generators of waste containing this contaminant
(≧100 kg/mo) must conform with EPA regulations
governing storage, transportation, treatment, and waste
disposal
2,4-Dichlorphenol Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2,4-DICHLORO-1-(2-PROPYNYLOXY)BENZENE
2-Chlorphenol
(+)-R-2-(2,4-Dichlorphenoxy)-propions?ure
Methyl-5-(2,4-dichlorphenoxy)-2-nitrobenzoat
5-chloro-alpha,alpha-bis(3,5-dichloro-2-hydroxyphenyl)-2-toluenesulfonic
3-[2,4-Dichlor-5-(1-methylethoxy)phenyl]-5-(1,1-dimethylethyl)-1,3,4-oxadiazol-2(3H)-on
2,4-Dichloro-5-nitrophenol
2,2'-Thiobis-(4,6-dichlor-phenol)
azafenidin
DICLOFOP-METHYL
Triclosan
Dichlorprop (ISO)
2,4-D
2,5-Dichlorphenol
Dichlofenthion (ISO)
O-(2,4-Dichlorophenyl)-O-ethyl-S-propyldithiophosphat
4-Chlorphenol
2,4-Dichlorphenyl-4-nitrophenylether