成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

9-α-Fluor-11-β,21-dihydroxy-16-α,17-α-isopropylidendioxypregna-1,4-dien-3,20-dion

Triamcinolone acetonide Struktur
76-25-5
CAS-Nr.
76-25-5
Bezeichnung:
9-α-Fluor-11-β,21-dihydroxy-16-α,17-α-isopropylidendioxypregna-1,4-dien-3,20-dion
Englisch Name:
Triamcinolone acetonide
Synonyma:
TRIAMCINOLONE ACETONIDE ACETATE;Triam;Refrigerator;KENALOG;Trymex;ERIC-1;Triacet;Azmacort;Nasacort;Aristogel
CBNumber:
CB4186553
Summenformel:
C24H31FO6
Molgewicht:
434.5
MOL-Datei:
76-25-5.mol

9-α-Fluor-11-β,21-dihydroxy-16-α,17-α-isopropylidendioxypregna-1,4-dien-3,20-dion Eigenschaften

Schmelzpunkt:
274-278°C (dec.)
alpha 
D23 +109° (c = 0.75 in chloroform)
Siedepunkt:
576.9±50.0 °C(Predicted)
Dichte
1.1517 (estimate)
Brechungsindex
1.5980 (estimate)
storage temp. 
Refrigerator
L?slichkeit
Practically insoluble in water, sparingly soluble in ethanol (96 per cent).
pka
12.87±0.10(Predicted)
Aggregatzustand
Solid
Farbe
White to Off-White
Wasserl?slichkeit
Soluble in DMSO or ethanol. Slightly soluble in water.
Merck 
9596
BCS Class
4
Stabilit?t:
Combustible. Incompatible with strong oxidizing agents.
InChIKey
YNDXUCZADRHECN-JNQJZLCISA-N
NIST chemische Informationen
Triamcinolone acetonide(76-25-5)
EPA chemische Informationen
Triamcinolone acetonide (76-25-5)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher T
R-S?tze: 61
S-S?tze: 53-45
WGK Germany  3
RTECS-Nr. TU3920000
TSCA  Yes
HS Code  29372290
Toxizit?t LD50 oral in mouse: 5gm/kg
Bildanzeige (GHS) GHS hazard pictogramsGHS hazard pictograms
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
H360 Kann die Fruchtbarkeit beeintr?chtigen oder das Kind im Mutterleib sch?digen. Fertility (Fruchtbarkeit) Kategorie 1 Achtung GHS hazard pictogramssrc="/GHS08.jpg" width="20" height="20" />
Sicherheit
P201 Vor Gebrauch besondere Anweisungen einholen.
P202 Vor Gebrauch alle Sicherheitshinweise lesen und verstehen.
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P270 Bei Gebrauch nicht essen, trinken oder rauchen.
P301+P312 BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.
P308+P313 BEI Exposition oder falls betroffen: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen.

9-α-Fluor-11-β,21-dihydroxy-16-α,17-α-isopropylidendioxypregna-1,4-dien-3,20-dion Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R61:Kann das Kind im Mutterleib sch?digen.

S-S?tze Betriebsanweisung:

S53:Exposition vermeiden - vor Gebrauch besondere Anweisungen einholen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).

Beschreibung

Triamcinolone acetonide is a synthetic corticosteroid. It decreases cytokine levels, the firing rate of sensory neurons, and mechanical hypersensitivity in a rat spinal nerve ligation model when used at a dose of 1.5 mg/kg prior to and following surgery for three days. Triamcinolone acetonide also decreases outflow facility in a mouse model of steroid-induced glaucoma when 20 μl of a 40 mg/ml suspension is administered subconjunctivally. Formulations containing triamcinolone acetonide are used in the treatment of diabetic macular edema.

Chemische Eigenschaften

White Solid

Definition

ChEBI: A synthetic glucocorticoid that is the 16,17-acetonide of triamcinolone. Used to treat various skin infections.

Indications

Triamcinolone acetonide (Aristocort, Kenalog) is a synthetic fluorinated corticosteroid.

Allgemeine Beschreibung

The three main metabolitesof triamcinolone acetonide (Azmacort, Nasacort) are 6β-hydroxytriamcinolone acetonide, 21-carboxytriamcinoloneacetonide, and 6β-hydroxy-21-carboxytriamcinolone acetonide.All are much less active than the parent compound.The 6β-hydroxyl group and the 21-carboxy group are bothstructural features that greatly reduce GC action. The increasedwater solubility of these metabolites also facilitatesmore rapid excretion.

Clinical Use

Triamcinolone acetonide used topically to treat various skin conditions, to relieve the discomfort of mouth sores, and by injection into joints to treat various joint conditions.Triamcinolone acetonide frequently is used by inhalation for the treatment of lung diseases (e.g., asthma).

Nebenwirkungen

The side effects of using Triamcinolone acetonide include:Skin dryness, flaking, crusting, burning, or blistering; Skin irritation; Skin soreness, itching, swelling, scaling, or severe redness; Scaling or redness near mouth; Skin thinning or bruising, especially in skin folds (like between the finger) or on the face (when directed to use it there); New or worsening pimples or acne; Skin burning and itching with tiny red blisters; Skin softening; Itching, pain, or burning sensation in hairy areas, or pus at the root of the hair; Increased hair growth on the legs, arms, back, or forehead; Lightening of skin tone; Red or purple lines on the arms, face, legs, groin, or trunk.

Sicherheitsprofil

Poison by subcutaneous and intraperitoneal routes. An experimental teratogen. Other experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits acrid smoke and toxic fumes of F-.

Stoffwechsel

Triamcinolone acetonide frequently is used by inhalation for the treatment of lung diseases (e.g., asthma). After inhalation, triamcinolone acetonide can become systemically available when the inhaled formulation is swallowed and absorbed unchanged from the GI tract, causing undesirable systemic effects. Triamcinolone acetonide that is swallowed is metabolized to 6β-hydroxytriamcinolone acetonide, 21-carboxytriamcinolone acetonide, and 21-carboxy-6β-hydroxytriamcinolone acetonide, all of which are more hydrophilic than their parent drug. Only approximately 1% of the dose was recovered from the urine as triamcinolone acetonide. Triamcinolone is not a major metabolite of triamcinolone acetonide in humans, suggesting that acetonide is resistant to hydrolytic cleavage. Triamcinolone acetonide is approximately eight times more potent than prednisolone.

9-α-Fluor-11-β,21-dihydroxy-16-α,17-α-isopropylidendioxypregna-1,4-dien-3,20-dion Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


9-α-Fluor-11-β,21-dihydroxy-16-α,17-α-isopropylidendioxypregna-1,4-dien-3,20-dion Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 620)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hangzhou Verychem Science And Technology Co.Ltd
+86-86-57188162785 13606544505
lucy@verychem.com China 1046 58
Nanjing Shizhou Biotechnology Co., Ltd
+86-15850508050 +86-15850508050
sean.lv@synzest.com China 323 58
Wuhan Fortuna Chemical Co., Ltd
+86-027-59207850
info@fortunachem.com China 5986 58
Zibo Hangyu Biotechnology Development Co., Ltd
+86-0533-2185556 +8617865335152
Mandy@hangyubiotech.com China 10986 58
Sigma Audley
+86-15937194204 +86-18126314766
nova@sh-teruiop.com China 493 58
Shaanxi TNJONE Pharmaceutical Co., Ltd
+8618092446649
sarah@tnjone.com China 1143 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886
info@dakenam.com China 18648 58
Beijing Cooperate Pharmaceutical Co.,Ltd
010-60279497
sales01@cooperate-pharm.com CHINA 1803 55
Shanghai Bojing Chemical Co.,Ltd.
+86-86-02137122233 +8613795318958
bj1@bj-chem.com China 299 55
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21639 55

76-25-5(9-α-Fluor-11-β,21-dihydroxy-16-α,17-α-isopropylidendioxypregna-1,4-dien-3,20-dion)Verwandte Suche:


  • ARISTODERM
  • 9ALPHA-FLUORO-11BETA,21-DIHYDROXY-16ALPHA,17-ISOPROPYLIDENEDIOXY-1,4-PREGNADIENE-3,20-DIONE
  • 9ALPHA-FLUORO-16ALPHA-HYDROXYPREDNISOLONE 16ALPHA,17ALPHA-ACETONIDE
  • 9ALPHA-FLUORO-11BETA,16ALPHA,17ALPHA,21-TETRAHYDROXY-1,4-PREGNADIENE-3,20-DIONE 16,17-ACETONIDE
  • 9a-fluoro-11b,16a,17a,21-tetrahydroxy-1,4-pregnadiene-3,20-dione 16,17-acetonide
  • 9a-fluoro-16a-hydroxyprednisolone 16a,17a-acetonide
  • ALPHA-FLUORO-11BETA,16ALPHA,17,21-TETRA-HYDROXYPREGNA-1,4-DIENE-3,20-DIONE
  • 1,4-PREGNADIEN-9-ALPHA-FLUORO-11-BETA, 16-ALPHA, 17,21-TETROL-3,20-DIONE-16,17-ACETONIDE
  • 1,4-PREGNADIEN-9ALPHA-FLUORO-11BETA,16ALPHA,17ALPHA,21-TETROL 3,20-DIONE 16,17-ACETONIDE
  • (11beta,16alpha)-9-Fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
  • (11beta,16alpha)-e)bis(oxy)]
  • 4b-Fluoro-6b-glycoloyl-5-hydroxy-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
  • 9-alpha-fluoro-11-beta,21-dihydroxy-16-alpha-isopropylidenedioxy-1,4-pregnad
  • 9-alpha-fluoro-16-alpha-17-alpha-isopropyledenedioxyprednisolone
  • 9alpha-Fluoro-16alpha-17alpha-isopropyledenedioxyprednisolone
  • 9alpha-Fluoro-16alpha-17alpha-isopropylidenedioxy-delta -1-hydrocortisone
  • 9-alpha-fluoro-16-alpha-17-alpha-isopropylidenedioxy-delta-1-hydrocortisone
  • 9alpha-Fluoro-16-hydroxyprednisolone acetonide
  • 9-alpha-fluoro-16-hydroxyprednisoloneacetonide
  • Acetospan
  • Adcortyl
  • Adcortyl A
  • Aristocort A
  • Aristocort acetonide
  • aristocortacetonide
  • component of Mycolog ii
  • component of Myco-triacet ii
  • component of Mytrex
  • component of Panolog
  • Coupe-A
  • Delphicort
  • triamsinoloneacetonide
  • Vetalog
  • triamcinolone16,17-acetonide
  • Triam-Injekt
  • Triamonide 40
  • Triamsinolone acetonide
  • TRIAMCINOLONE ACETONIDE
  • TRICINOLON
  • Adcortyl, Azmacort, Delphicort, Extracort, Ftorocort, Kenacort-A, Tramacin, Triam, Tricinolon, Vetalog, Volon A, Volonimat,
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11,21-dihydroxy-16,17-(1-methylethylidene)bis(oxy)-, (11.beta.,16.alpha.)-
  • Volon A
  • Volon A 40
  • Volonimat
  • RINETON
  • 16alpha-Hydroxy-9alpha-fluoroprednisolone acetonide
  • Triamcinolone acetonide,>=99%
  • Triamcinoione acetonide
  • Triamcinolone Acetonide (500 mg)
  • (11β,16α)-9-Fluoro-11,21-dihydroxy-16,17-[(1-Methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione
  • 9α-Fluoro-16α-hydroxyprednisolone 16α,17α-acetonide
  • TriaMcinolon Acetonide
  • TriaMcinolon-6-d1 Acetonide-d6
  • TriaMcinolone Acetonide USP
  • TriaMcinolone acetonid
  • Triamcinolone acetonide Solution, 100ppm
  • Triamcinolone acetonide for system suitability
  • Anti-TACC3, C-Terminal antibody produced in rabbit
Copyright 2019 ? ChemicalBook. All rights reserved