Etidronisure
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- CAS-Nr.
- 2809-21-4
- Bezeichnung:
- Etidronisure
- Englisch Name:
- Etidronic Acid
- Synonyma:
- HEDP;ETIDRONIC ACID;DEQUEST 2010;HEDP2NA;ehdp;1-diphosphonic acid;1-HYDROXYETHYLIDENE-1;1-HYDROXYETHANE-1,1-DIPHOSPHONIC ACID;HEDPA;hydroxy ethylidene diphosphoric acid
- CBNumber:
- CB4719658
- Summenformel:
- C2H8O7P2
- Molgewicht:
- 206.03
- MOL-Datei:
- 2809-21-4.mol
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Etidronisure Eigenschaften
- Schmelzpunkt:
- 198~199℃
- Siedepunkt:
- 578.8±60.0 °C(Predicted)
- Dichte
- 1.45 (60% aq.)
- Dampfdruck
- 0Pa at 25℃
- storage temp.
- Sealed in dry,Room Temperature
- L?slichkeit
- Methanol (Slightly), Water (Slightly)
- pka
- 1.35, 2.87, 7.03, 11.3(at 25℃)
- Aggregatzustand
- Powder
- Farbe
- white
- PH
- pH (1.7→100, 25℃) : 1.3～1.8
- Wasserl?slichkeit
- Soluble in water.
- Merck
- 14,3863
- BRN
- 1789291
- Stabilit?t:
- Stable. Incompatible with strong oxidizing agents.
- InChIKey
- DBVJJBKOTRCVKF-UHFFFAOYSA-N
- LogP
- -3.5
- CAS Datenbank
- 2809-21-4(CAS DataBase Reference)
- EPA chemische Informationen
- Etidronic acid (2809-21-4)
Etidronisure Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R37/38:Reizt die Atmungsorgane und die Haut.
R41:Gefahr ernster Augensch?den.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S39:Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
light beige powder
Verwenden
Etidronate (Didronel) is a human protein tyrosine phosphatase inhibitor with IC50 of 0.2 μM.
Definition
ChEBI: A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.
in vitro
Etidronic acid (Etidronate) (10 mM, 24 h) shows cytotoxicity, causes a decrease in the S-phase population and an increase in the G2/M population, and induces p53 mutation in MCF-7 cells.
Etidronic acid (100 nM, 24 h) induces osteoclast apoptosis, which displays characteristics of apoptosis, including chromatin condensation and changed cellular and nuclear morphology, detected by fluorescence microscopy.
Etidronisure Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Etidronisure Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 511)Lieferanten
2809-21-4(Etidronisure)Verwandte Suche:
- ETHANE-1-HYDROXY-1,1-DIPHOSPHONIC ACID, 95+%
- (1-Hydroxyethylidene)biphosphonic acid
- Hydroxyethylidene Diphosphonic acid (HEDP)
- 1-Hydroxyethylidene-1,1-diphosphonicacid,min.95%HEDP
- 1-Hydroxyethan-1,1-diphosphonsure
- 1-HYDROXYETHYLIDENE-1,1-DIPHOSPHONIC ACID HEDP
- 1-Hydroxyethylidene-1,1-bis-(phosphonic acid)
- 1-HYDROXYETHYLIDENE-1,1-DIPHOSPHONIC ACID, 98% HEDP
- 1-Hydroxyethane-1,1-diphosphonic Acid (ca. 60% in Water, ca. 4.2mol/L)
- 1-hydroxyethylidenebis(phosphoric acid)
- 1-Hydroxyethylidene-1,1-diphosphonic aci
- 1-hydroxy ethylene-1,1'-diphosphonic acid
- 1-Hydroxyethane-1,1,-diphosphonic acid, 1-Hydroxyethylidenediphosphonic acid
- Hydroxyethane diphosphonic acid,1-
- (1-hydroxyethylene)diphosphonicacid
- (1-hydroxyethylidene)bis-phosphonicaci
- (1-hydroxyethylidene)di-phosphonicaci
- (hydroxyethylidene)diphosphonicacid
- 1,1,1-ethanetrioldiphosphonate
- dequest2015
- dequestz010
- ethane-1-hydroxy-1,1-diphosphonate
- ferrofos510
- 1000sl
- 1-hydroxy-1,1-diphosphonoethane
- 1-Hydroxyethanediphosphonica
- 1-hydroxyethanediphosphonicacid
- 1-Hydroxyethylene-1,1-diphosphoricacid
- hydroxyethane-1,1-diphosphonicacid
- hydroxyethanediphosphonicacid
- Hydroxyethylidene-1,1-diphosphonicacid(HEDP)
- oxyethylidenediphosphonicacid
- Phosphonicacid,(1-hydroxyethylidene)bis-
- phosphonicacid,1-hydroxy-1,1-ethanediylester
- turpinalsl
- 1-HYDROXYETHYLIDENE-1,1-DIPHOSPHONIC ACID
- 1-HYDROXYETHANE-1,1-BIS(PHOSPHONIC ACID)
- 1-HYDROXYETHYLIDENEDIPHOSPHONIC ACID
- (1-HYDROXY-1-PHOSPHONO-ETHYL)-PHOSPHONIC ACID
- ETHANE-1-HYDROXY-1,1-DIPHOSPHONIC ACID
- Etidronic Acid Monohydrate (1 g)
- 1-Hydroxyethylidene-1,1-Diphosphonic Acid/HEDP Powder
- (1-Hydroxyethane-1,1-diyl)diphosphonic acid
- 1-Hydroxyethylidene-1,1-diphosphonic Acid
Etidronic Acid
- Etidronate (Didronel)
- Etidronic acid,60% in water
- 1-Hydroxyethane-1,1-diphosphonic acid, 60 wt.% solution in H2O
- Etidronic acid Monohydrate (HEDP)
- Etidronic acid 60% aqueous solution
- HDEPA
- OEDFK
- HydroxyEthylidene-1,1-DiphosphonicAcid
- Phosphonic acid, P,P'-(1-hydroxyethylidene)bis-
- 1-Hydroxy Ethylidene-1, 1-Diphosphonic Acid (Hedp)60%
- Etidronic acid 50% 60% 90%
- HEDP 1-Hydroxy Ethylidene-1,1-Diphosphonic Acid
- Scale and Corrosion Inhibitor HEDP 60% 90%
- 60% 1-Hydroxyethane-1,1-bis(phosphonic acid) Solution
