2-Amino-5-phenyl-4(5H)-oxazolon Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.
R34:Verursacht Ver?tzungen.
R11:Leichtentzündlich.
S-S?tze Betriebsanweisung:
S16:Von Zündquellen fernhalten - Nicht rauchen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
Chemische Eigenschaften
White Solid
Verwenden
A CNS stimulant. Controlled Substance
Definition
ChEBI: A member of the class of 1,3-oxazoles that is 1,3-oxazol-4(5H)-one which is substituted by an amino group at position 2 and by a phenyl group at position 5. A central nervous system stimulant, it was used to treat hyperactivity disorders
in children, but withdrawn from use following reports of serious hepatotoxicity.
Weltgesundheitsorganisation (WHO)
Pemoline was introduced in 1975 for the treatment of attentiondeficit
disorder. Because of its central stimulating effects it has also been used in
weight control in combination with anorectic agents, laxatives.
Allgemeine Beschreibung
Pemoline, 2-amino-5-phenyl-4(5H)-oxazolone (Cylert), hasa unique structure.
The compound is described as having an overall effect onthe CNS like that of methylphenidate. Pemoline requires 3to 4 weeks of administration, however, to take effect. A partialexplanation for the delayed effect may be that one of theactions of the agent, as observed in rats, is to increase therate of synthesis of DA.
Biologische Aktivit?t
Long-acting central stimulant that induces self-injurious behavior in rats. Acts as an indirect monoamine agonist.
2-Amino-5-phenyl-4(5H)-oxazolon Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
