Brinzolamide-d5
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Brinzolamide-d5 Eigenschaften
- storage temp.
- Refrigerator
- L?slichkeit
- Ethanol
- Aggregatzustand
- Solid
- Farbe
- Crystalline
Sicherheit
Brinzolamide-d5 Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Brinzolamide-d5 is intended for use as an internal standard for the quantification of brinzolamide by GC- or LC-MS. Brinzolamide is a potent inhibitor of carbonic anhydrase II (CAII) and CAIV (IC50s = 3.19 and 45.3 nM, respectively). It is selective for CAII and CAIV over CAI (IC50 = ~1,365 nM). Brinzolamide (30 mg/kg) reduces intestinal charcoal meal progression by 44% and prolongs pentobarbital sodium-induced sleep time by 35% in mice. Topical administration of brinzolamide (0.25, 0.5, and 1 mg/eye) reduces intraocular pressure in a rabbit model of spontaneous ocular hypertension. It also reduces intraocular pressure in a cynomolgus monkey model of argon laser trabeculoplasty-induced ocular hypertension. Formulations containing brinzolamide have been used in the treatment of glaucoma and ocular hypertension.Chemische Eigenschaften
Crystalline SolidVerwenden
Carbonic anhydrase inhibitor. Antiglaucoma agent.Brinzolamide-d5 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Brinzolamide-d5 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 22)Lieferanten
Firmenname | Telefon | Land | Produktkatalog | Edge Rate | |
---|---|---|---|---|---|
Chemsky(shanghai)International Co.,Ltd. | 021-50135380 |
shchemsky@sina.com | China | 32321 | 50 |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 |
info@efebio.com | China | 9806 | 58 |
Hubei Yangxin Medical Technology Co., Ltd. | 15374522761 |
3003392093@qq.com | China | 8706 | 55 |
Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 |
sales@glpbio.cn | China | 6777 | 58 |
ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 |
sales@chemegen.com | China | 11218 | 58 |
Energy Chemical | 021-58432009 400-005-6266 |
marketing1@energy-chemical.com | China | 44807 | 58 |
Shanghai isotope chemical co.,ltd | 021-021-51600108 13062666369 |
sales@chinaisotope.com | China | 4271 | 58 |
Nanjing Shizhou Biology Technology Co.,Ltd | 17301488900 |
judy.xia@synzest.com | China | 12582 | 58 |
58896805 |
7993601name@qq.com | CHINA | 15620 | 58 | |
Shanghai Weiyite Biotechnology Co., Ltd | 15317051735 |
josie@wytsci.com | China | 7543 | 58 |
1217651-02-9()Verwandte Suche:
(2S-cis)-5-[2-(Dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-onmonohydrochlorid
Diltiazem hydrochloride
(2S-cis)-5-[2-(Dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-on
(2R-cis)-3-Acetoxy-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-onmonohydrochlorid
- [2H5]-Brinzolamide
- Brinzolamide-d5
- (R)-4-((ethyl-d5)amino)-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide
- 1217651-02-9
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