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Cytidin-3'-(dihydrogenphosphat)

Cytidine 5’-monophosphate Struktur
63-37-6
CAS-Nr.
63-37-6
Bezeichnung:
Cytidin-3'-(dihydrogenphosphat)
Englisch Name:
Cytidine 5’-monophosphate
Synonyma:
CMP;CYTIDYLIC ACID;CYTIDINE 5'-MONOPHOSPHATE;5'-CYTIDINE MONOPHOSPHATE;((2R,3S,4R,5R)-5-(4-aMino-2-oxopyriMidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)Methyl dihydrogen phosphate;C-5-P;5'-CMP;C-5'-P;CMP.H2;3'-CMP
CBNumber:
CB2700845
Summenformel:
C9H14N3O8P
Molgewicht:
323.2
MOL-Datei:
63-37-6.mol

Cytidin-3'-(dihydrogenphosphat) Eigenschaften

Schmelzpunkt:
~222 °C (dec.)
Siedepunkt:
678.1±65.0 °C(Predicted)
Dichte
2.15±0.1 g/cm3(Predicted)
Brechungsindex
9.8 ° (C=1, 0.5mol/L Na2HPO4)
storage temp. 
2-8°C
L?slichkeit
Water (Slightly, Heated)
pka
pK2:4.39(0);pK3:6.62(+1) (25°C)
Aggregatzustand
crystalline
Farbe
White
Wasserl?slichkeit
soluble
BRN 
46982
InChI
InChI=1S/C9H14N3O8P/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H2,10,11,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
InChIKey
IERHLVCPSMICTF-JDNPWWSISA-N
SMILES
P(OC[C@H]1O[C@@H](N2C=CC(N)=NC2=O)[C@H](O)[C@@H]1O)(O)(O)=O
CAS Datenbank
63-37-6(CAS DataBase Reference)
EPA chemische Informationen
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xn,Xi
R-S?tze: 20/21/22-36/37/38
S-S?tze: 24/25-37/39-36-26
WGK Germany  3
RTECS-Nr. HA3980000
10-21
HS Code  29349990
Toxizit?t LD50 intraperitoneal in mouse: > 1gm/kg
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

Cytidin-3'-(dihydrogenphosphat) Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R20/21/22:Gesundheitssch?dlich beim Einatmen,Verschlucken und Berührung mit der Haut.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-S?tze Betriebsanweisung:

S24/25:Berührung mit den Augen und der Haut vermeiden.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.

Chemische Eigenschaften

white crystalline powder

Verwenden

A constituent of nucleic acids. It was isolated from yeast nucleic acid.

Definition

ChEBI: A pyrimidine ribonucleoside 5'-monophosphate having cytosine as the nucleobase.

Vorbereitung Methode

As a key intermediate in preparing several nucleotide derivatives, cytidine 5′-monophosphate (5′-CMP) is widely applied in food and pharmaceutical industries. Enzymatic synthesis of 5′-CMP is catalyzed by cytidine kinase (CK, EC 2.7.1.213), a type of nucleoside kinase that belongs to the PfkB family. Li et al. constructed a highly efficient biosynthesis system for manufacturing 5′-CMP in vitro. CK was used for the biotransformation of cytidine to 5′-CMP, while polyphosphate kinase (PPK) was coupled for adenosine triphosphate regeneration. Both CK and PPK were selected from extremophiles, possessing great potential for biocatalytic synthesis. After optimization, 96 mM 5′-CMP was produced within 6 h, and the yield reached nearly 100%[1].

Cytidin-3'-(dihydrogenphosphat) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Cytidin-3'-(dihydrogenphosphat) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 663)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hangzhou Weitai Biological Pharmaceutical Co.,Ltd.
+8613282012786
sales@weitai-pharmaceutical.com China 61 58
Hangzhou Meiya Pharmaceutical Co Ltd
+86-021-33686691 +8618001850931
sales@meiyapharm.com China 58 58
Xinxiang Aurora Biotechnology Co.,Ltd.
+86-0086-0373-3088722 +8618637352520
info@aurora-biotech.com China 93 58
Hebei Weibang Biotechnology Co., Ltd
+8615531157085
abby@weibangbio.com China 8810 58
Hebei Mojin Biotechnology Co., Ltd
+86 13288715578 +8613288715578
sales@hbmojin.com China 12835 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325
sales1@chuanghaibio.com China 5889 58
Hebei Kingfiner Technology Development Co.Ltd
+86-15532196582 +86-15373005021
lisa@kingfinertech.com China 3010 58
Chongqing Zhihe Biopharmaceutical Co., Ltd.
+86-18580541567; +8618580541567
sales@zhswyy.com China 301 58
airuikechemical co., ltd.
+undefined86-15315557071
sales02@sdzhonghuimaterial.com China 983 58
Hebei Saisier Technology Co., LTD
+86-18400010335 +86-18034520335
admin@hbsaisier.cn China 1015 58

63-37-6(Cytidin-3'-(dihydrogenphosphat))Verwandte Suche:


  • C-5'-P
  • C-5-P
  • CMP MONOHYDRATE
  • CYTIDINE-5'-MONOPHOSPHATE MONOHYDRATE
  • CYTIDINE-5'-MONOPHOSPHORIC ACID
  • 5'-CYTIDYLIC ACID
  • 5'-CYTIDYLIC ACID MONOHYDRATE
  • 5'-CMP
  • Cytidine Monophosphate and salts
  • Cytidine 5'-monophate
  • CYTIDINE 5'-MONOPHOSPHATE FREE ACIDSIGMA GRADE FRO
  • Cmp:Cytidine-5'-MonophosphateFreeAcid
  • CYTIDINE 5'-MONOPHOSPHATE, FREE ACID (5'-CMP)
  • [5-(4-amino-2-oxo-pyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxyphosphonic acid
  • 5''-CYTIDINE MONOPHOSPHORIC ACID(FREE ACID)
  • Cytidylic acid、CMP
  • Cytidine-5''-monophosphoric acid (and/or unspecified salts)
  • 5'-cytidylate monophosphate
  • Cytidine 3'-(dihydrogen phosphate)
  • 5-CYTIDYLICACID(5-CMP)
  • Cytidine 5’-Monophosphate(CMP)
  • CYTIDINE-5-MONOPHOSPHORIC ACID extrapure
  • 5μ-CMP, 5μ-Cytidylic acid, C-5μ-P
  • Cytidine mono(dihydrogen phosphate)
  • Cytodine monophosphate: (Cytidine 5-monophosphate free acid)
  • Cytidine-5'-monophosphoric acid hydrate,99%
  • ((2R,3S,4R,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl di
  • 5'-CMP 5'-Cytidylic acid C-5'-P CMP
  • 5'-CMP(Cytidine 5'-monophosphate free acid)
  • Cytidine-5'monophosphate(CMP),FREE ACID
  • CMP.H2
  • cytidylic acid ,5'-cMp
  • cytidine-5Monophophate
  • cmp(nucleotide)
  • cytidine5’-(dihydrogenphosphate)
  • cytidine5’-phosphate
  • cytidine5’-phosphoricacid
  • cytidinemonophosphate
  • CYTIDINE-5'-MONOPHOSPHATE(P)
  • ((2R,3S,4R,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihyd
  • 5'-CMPH2
  • 5'-Cytidylic Acid (500 mg)
  • 5 ' - Cyticline Monophosphoric Acid (Free Acid )
  • 4-aMino-1-(O5-phosphono-pentofuranosyl)-1H-pyriMidin-2-one
  • Cytidylic acid SynonyMs 5'-cytidylate Monophosphate
  • Cytidine 5'-monophosphate (5'-CMP)
  • Cytidine 5′-monophosphate, synthetic, 99%
  • 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-5-yldihydrogenphosphate
  • Cytidine -5'- Monophosphate(CMP-H)
  • Cytidine 5'-Monophosphate >
  • Cytidylic acid Solution, 100μg/mL
  • -cytidylate monophosphate
  • 5'-CYTIDYLATE MONOPHOSPHATE(CMP)
  • Cytidylic acid USP/EP/BP
  • CYTIDINE-5'-MONOPH0SPHATE
  • 5'-Cytidine monophosphate free acid
  • ((2R,3S,4R,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrog
  • Cytidine-5-Monophosphate (5-CMP) extrapure, 99%
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