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Enoximone

Enoximone Struktur
77671-31-9
CAS-Nr.
77671-31-9
Englisch Name:
Enoximone
Synonyma:
Perfan;Pedane;RMI-17043;ENOXIMONE;MDL-17043;Fenoximone;Enoximone USP/EP/BP;Enoximone, 10 mM in DMSO;4-Methyl-5-(4-(methylthio)benzoyl)-1H-imidazol-2(3H)-one;1,3-DIHYDRO-4-METHYL-5-[4-METHYLTHIOBENZOYL]-2H-IMIDAZOL-2-ONE
CBNumber:
CB2682723
Summenformel:
C12H12N2O2S
Molgewicht:
248.3
MOL-Datei:
77671-31-9.mol

Enoximone Eigenschaften

Schmelzpunkt:
255-258°C
Dichte
1.33
storage temp. 
Sealed in dry,Room Temperature
L?slichkeit
DMSO: 28 mg/mL, soluble
pka
10.37±0.70(Predicted)
Aggregatzustand
solid
Farbe
light yellow
CAS Datenbank
77671-31-9(CAS DataBase Reference)

Sicherheit

RIDADR  3249
WGK Germany  3
HazardClass  6.1(b)
PackingGroup  III

Enoximone Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Enoximone is a phosphodiesterase inhibitor indicated for selective use as a cardiostimulant in heart transplant patient maintenance. It is currently being investigated for other indications including acute congestive heart failure.

Verwenden

Enoximone is a phosphodiesterase inhibitor used in the treatment of congestive heart failure and is selective to phosphodiesterase 3. Potent PDE-3 inhibitor.

Biologische Aktivit?t

Inhibitor of type III phosphodiesterase (PDE3). Increases intracellular cyclic AMP (cAMP) concentrations and enhances myocardial contractility. Also induces concentration-dependent vasodilation in vitro .

Enoximone Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Nitrosylhydroxid Ethylacetat

Downstream Produkte

Enoximone Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 105)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 33024 60
CONIER CHEM AND PHARMA LIMITED 		+8618523575427
 sales@conier.com China 49732 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32159 58
Shaanxi Dideu Medichem Co. Ltd 		+86-029-89586680 +86-18192503167
 1026@dideu.com China 7722 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38630 58
Hu Bei Jiutian Bio-medical Technology CO.,Ltd 		027-88013699 17354350817
 Ryan@jiutian-bio.com China 6001 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525
 masar@topule.com China 8467 58
Aladdin Scientific
tp@aladdinsci.com United States 57505 58
Shaanxi Xianhe Biotech Co., Ltd 		+8617709210191
 Jerry@xhobio.com China 882 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131957 58

77671-31-9()Verwandte Suche:

  • ENOXIMONE
  • 2H-Imidazol-2-one, 1,3-dihydro-4-methyl-5-(4-(methylthio)benzoyl)-
  • Fenoximone
  • MDL-17043
  • Pedane
  • Perfan
  • RMI-17043
  • 4-methyl-5-(4-methylsulfanylbenzoyl)-1,3-dihydroimidazol-2-one
  • 1,3-DIHYDRO-4-METHYL-5-[4-METHYLTHIOBENZOYL]-2H-IMIDAZOL-2-ONE
  • 4-Methyl-5-[4-(methylthio)benzoyl]-1,3-dihydro-2H-imidazol-2-one
  • Enoximone USP/EP/BP
  • 4-Methyl-5-(4-(methylthio)benzoyl)-1H-imidazol-2(3H)-one
  • inhibit,Enoximone,bronchodilatory,CD11b,eosinophils,vasodilating,Phosphodiesterase (PDE),airway,cAMP,PDE3,PDE4A,Inhibitor,anti-inflammatory,Antiasthma
  • Enoximone, 10 mM in DMSO
  • 77671-31-9
  • BioChemical
  • Cell Signaling and Neuroscience
  • G Proteins and Cyclic Nucleotides
  • Phosphodiesterase Inhibitors
  • Cyclic Nucleotide Metabolism
  • Cell Biology
  • APIs
  • API
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