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Tubocuraranium, 6,6',7',12'-Tetramethoxy-2,2,2',2'-tetramethyl-, Dijodid

TETRANDRINI DIMETHIODIDUM Struktur
7601-55-0
CAS-Nr.
7601-55-0
Bezeichnung:
Tubocuraranium, 6,6',7',12'-Tetramethoxy-2,2,2',2'-tetramethyl-, Dijodid
Englisch Name:
TETRANDRINI DIMETHIODIDUM
Synonyma:
Metubine;metubineiodide;methyl-curarin;metocurineiodide;TETRANDRINI DIMETHIODIDUM;dimethyltubocurarineiodide;Dimethylchondrocurarineiodide;d-tubocurarineiodidedimethylether;dimethyletherofd-tubocurarineiodide;(+)-o,o’-dimethylchondrocurarinediiodide
CBNumber:
CB2676607
Summenformel:
C40H48I2N2O6
Molgewicht:
906.63
MOL-Datei:
7601-55-0.mol

Tubocuraranium, 6,6',7',12'-Tetramethoxy-2,2,2',2'-tetramethyl-, Dijodid Eigenschaften

alpha 
D22 +148 to +158° (c = 0.25)

Sicherheit

RIDADR  3249
HazardClass  6.1(b)
PackingGroup  III

Tubocuraranium, 6,6',7',12'-Tetramethoxy-2,2,2',2'-tetramethyl-, Dijodid Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Neuromuscular blocking agent.

Allgemeine Beschreibung

Metocurine iodide, ( )-O,O -dimethylchondrocurarine diiodide (Metubine iodide),is prepared from natural crude curare by extracting the curarewith methanolic potassium hydroxide. When theextract is treated with an excess of methyl iodide, the ( )-tubocurarine is converted to the diquaternary dimethylether and crystallizes out as the iodide (see “TubocurarineChloride”). Other ethers besides the dimethyl ether havebeen made and tested. For example, the dibenzyl ether wasone third as active as tubocurarine chloride, and the diisopropylcompound had only one half the activity. For comparison,the dimethyl ether has approximately 4 times theactivity of tubocurarine chloride.
The pharmacological action of this compound is the sameas that of tubocurarine chloride, namely, a nondepolarizingcompetitive blocking effect on the motor end plate of skeletalmuscles. It is considerably more potent than d-tubocurarine,however, and has the added advantage of exerting much lesseffect on respiration. The effect on respiration is not a significantfactor in therapeutic doses. Accidental overdosage iscounteracted best by forced respiration.

Tubocuraranium, 6,6',7',12'-Tetramethoxy-2,2,2',2'-tetramethyl-, Dijodid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Tubocuraranium, 6,6',7',12'-Tetramethoxy-2,2,2',2'-tetramethyl-, Dijodid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 14)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shaanxi Dideu Medichem Co. Ltd
+86-29-81148696 +86-15536356810
1022@dideu.com China 3882 58
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714
fandachem@gmail.com China 9218 55
Hangzhou Yuhao Chemical Technology Co., Ltd 0571-82693216
info@yuhaochemical.com China 9387 52

7601-55-0(Tubocuraranium, 6,6',7',12'-Tetramethoxy-2,2,2',2'-tetramethyl-, Dijodid)Verwandte Suche:


  • TETRANDRINI DIMETHIODIDUM
  • (+)-o,o’-dimethylchondrocurarinediiodide
  • metubineiodide
  • Tubocuraranium, 6,6',7',12'-tetramethoxy-2,2,2',2'-tetramethyl-, diiodide
  • 6,6’,7’,12’-tetramethoxy-2,2,2’,2’-tetramethyl-tubocuraraniudiiodide
  • 6,6’,7’,12’-tetramethoxy-2,2,2’,2’-tetramethyltubocuraraniumdiiodide
  • dimethyletherofd-tubocurarineiodide
  • dimethyltubocurarineiodide
  • d-tubocurarineiodidedimethylether
  • methyl-curarin
  • metocurineiodide
  • Dimethylchondrocurarineiodide
  • Metubine
  • 7601-55-0
  • C40H48N2O62I
  • C40H48I2N2O6
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