Sodium taurodeoxycholate hydrate Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Sodium taurodeoxycholate hydrate is a bile salt-related, anionic detergent used for isolation of membrane proteins including inner mitochondrial membrane proteins. It has also been used in a study to investigate polymorphic behavior in protein surfactant mixtures.
Sodium taurodeoxycholate hydrate has been used in a study to assess the effect of submicellar concentrations of bile salts on the lipid bilayer membrane. It has also been used in a study to investigate polymorphic behavior in protein-surfactant mixtures.

Verwenden

A hydrate form of sodium taurodeoxycholate (T009005), a steroid which rescues human colon cancer cells from apoptosis by activating EGFR-dependent PI3K/Akt signaling.

Allgemeine Beschreibung

Sodium tauroursodeoxycholate is a bile salt which is naturally present in the small bowel.

l?uterung methode

The Na salt is dissolved in the smallest volume of H2O, a saturated solution of aqueous NaCl/Et2O is added and the mixture is stored at 0o for 24hours. Then shake the mixture well, keep it in the cold for another day and filter the crystals with gentle shaking, wash them with ice-cold saturated aqueous NaCl saturated with Et2O, dry them over CaCl2 and extract them with absolute EtOH. Add ~10mL of H2O to the solid followed by enough Et2O to incipient cloudiness. Store it overnight at 0o. Add ice-cold Et2O to make 250mL, collect the crystals, wash them with Et2O then pet ether and dry them in air. The purification can be repeated with NaCl and Et2O with ~85% recovery. NB: precipitation will not occur unless enough H2O is present. Its solubility in H2O is 10%. [Cortese J Am Chem Soc 59 2532 1937.] The free acid has m 141-144o. [Norman Ark Kemi 8 331 1956.] It forms mixed micelles and solubilises some membrane proteins [Hajjar et al. J Biol Chem 2 5 8 192 1983]. [Beilstein 10 IV 1611.]

Sodium taurodeoxycholate hydrate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Sodium taurodeoxycholate hydrate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.	+86-18600796368 +86-18600796368	sales@sjar-tech.com	China	395	58
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3009	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32951	60
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5906	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49374	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29814	58
Antai Fine Chemical Technology Co.,Limited	18503026267	info@antaichem.com	CHINA	9636	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32070	58
Hubei Ipure Biology Co., Ltd	+8613367258412	ada@ipurechemical.com	China	10319	58

207737-97-1()Verwandte Suche:

---

• 2-[[(3alpha,5beta,12alpha)-3,12-Dihydroxy-24-oxocholan-24-yl]amino]-ethanesulfonic acid monosodium salt hydrate
• TAURODEOXYCHOLIC ACID SODIUM SIGMAULTRA
• 2-([3α,12α-dihydroxy-24-oxo-5β-cholan-24-yl]amino)ethanesulfonic acid
• Taurodeoxycholic acid hydrate sodium salt, 2-([3α,12α-Dihydroxy-24-oxo-5β-cholan-24-yl]amino)ethanesulfonic acid
• N-(Deoxycholyl)taurine sodium salt, Taurodeoxycholic acid sodium salt, 3α,12α-Dihydroxy-5β-cholan-24-oic acid N-(2-sulfoethyl)amide sodium salt
• Sodium taurodeoxycholate hydrate,2-([3α,12α-Dihydroxy-24-oxo-5β-cholan-24-yl]amino)ethanesulfonic acid, Taurodeoxycholic acid sodium salt hydrate
• Ethanesulfonic acid,2-[[(3a,5b,12a)-3,12-dihydroxy-24-oxocholan-24-yl]aMino]-, sodiuM salt, hydrate (1:1:)
• 3α,12α-Dihydroxy-5β-cholan-24-oic acid N-(2-sulfoethyl)amide sodium salt
• N-(Deoxycholyl)taurine sodium salt
• 2-([3α,12α-Dihydroxy-24-oxo-5β-cholan-24-yl]amino)ethanesulfonic acid, Taurodeoxycholic acid sodium salt hydrate
• SODIUM TAURODEOXYCHOLATE HYDRATE BIO
• SODIUM TAURODEOXYCHOLATE HYDRATE
• Taurodeoxycholic Acid sodium salt hydrat
• Taurodeoxycholic Acid-[d6] Sodium Salt
• Taurodeoxycholic acid sodium hydrate
• Sodium Taurodeoxycholate Hydrate See T009005
• Sodium taurodeoxycholate, ≥99%
• Taurodeoxycholic Acid-D4 Sodium Salt DiHydrateQ: What is Taurodeoxycholic Acid-D4 Sodium Salt DiHydrate Q: What is the CAS Number of Taurodeoxycholic Acid-D4 Sodium Salt DiHydrate Q: What is the storage condition of Taurodeoxycholic Acid-D4 Sodium Salt DiHydrate Q: What are the applications of Taurodeoxycholic Acid-D4 Sodium Salt DiHydrate
• Sodium Taurodeoxycholate HydrateQ: What is Sodium Taurodeoxycholate Hydrate Q: What is the CAS Number of Sodium Taurodeoxycholate Hydrate Q: What is the storage condition of Sodium Taurodeoxycholate Hydrate Q: What are the applications of Sodium Taurodeoxycholate Hydrate
• sodium 2-{[(3alpha,5beta,12alpha)-3,12-dihydroxy-24-oxocholan-24-yl]amino}ethanesulfonate hydrate
• Sodium Taurodeoxycholate Hydrate (STDC Hydrate) extrapure, 97%
• Sodium 2-[[(3α,5β,12α)-3,12-dihydroxy-24-oxocholan-24-yl]amino]ethanesulfonate hydrate (1:1:?)
• Sodium 2-((R)-4-((3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)ethanesulfonate xhydrate
• 2H6]-Taurodeoxycholic Acid Sodium Salt
• 12α
• 5β
• sodium 2-[[(3α
• Taurodeoxycholic Acid-[d6] Sodium Salt in Methanol
• Taurodeoxycholic Acid Sodium Salt Hydrate in Methanol
• 207737-97-1
• C26H46NO6SxH2ONa