20ALPHA-HYDROXYCHOLESTEROL
|
|
|
- CAS-Nr.
- 516-72-3
- Englisch Name:
- 20ALPHA-HYDROXYCHOLESTEROL
- Synonyma:
- C05500;20-hydroxycholesterol;20A-HYDROXYCHOLESTEROL;20α-Hydroxy Cholesterol;Cholesterol Impurity 32;5-Cholestene-3B,20a-diol;5-cholestene-3β,20α-diol;Cholest-5-ene-3,20a-diol;Cholest-5-ene-3β,20-diol;20[S]-HYDROXYCHOLESTEROL
- CBNumber:
- CB2372501
- Summenformel:
- C27H46O2
- Molgewicht:
- 402.65
- MOL-Datei:
- 516-72-3.mol
|
20ALPHA-HYDROXYCHOLESTEROL Eigenschaften
- Schmelzpunkt:
- 136-137°C
- Siedepunkt:
- 512.3±23.0 °C(Predicted)
- Dichte
- 1.03±0.1 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,2-8°C
- L?slichkeit
- Soluble in DMSO or in Ethanol.
- Aggregatzustand
- Solid
- pka
- 15.04±0.70(Predicted)
- Farbe
- White
- Stabilit?t:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Sicherheit
20ALPHA-HYDROXYCHOLESTEROL Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
20(S)-hydroxy Cholesterol is an allosteric agonist of the smoothened (Smo) receptor that activates the hedgehog (Hh) signaling pathway with an EC
50 value of approxiately 3 μM in a gene transcription reporter assay using NIH3T3 cells. 20(S)-hydroxy Cholesterol is necessary for normal Hh signaling. It induces Smo accumulation in primary cilia, an early event in signaling, and binds to the extracellular, cysteine-rich domain of Smo. 20(S)-hydroxy Cholesterol also stimulates osteogenic differentiation of pluripotent bone marrow stromal cells, a process mediated
via Hh and Notch signaling.
Chemische Eigenschaften
White Solid
Verwenden
A metabolite of Cholesterol. Cholesterol oxidation product having cytotoxicity effects
Definition
ChEBI: An oxysterol that is cholesterol substituted by a hydroxy group at position 20.
20ALPHA-HYDROXYCHOLESTEROL Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
20ALPHA-HYDROXYCHOLESTEROL Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 67)Lieferanten
516-72-3()Verwandte Suche:
- 20alpha-Hydroxycholesterol (not deuterated)
- 5-Cholestene-3B,20a-diol
- Cholest-5-ene-3,20-diol, (3.beta.)-
- 5-cholestene-3β,20α-diol
- (3S,8S,9S,10R,13S,14S,17S)-17-[(2R)-2-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
- 20α-Hydroxycholesterol (not deuterated)
- (20S)-Cholest-5-ene-3,20-diol
- (3)-Cholest-5-ene-3,20-diol
- 20S-Cholest-5-ene-3,20-diol
- Cholest-5-ene-3,20a-diol
- (20S)-20-Hydroxycholesterol
- Cholest-5-ene-3β,20-diol
- C05500
- 20A-HYDROXYCHOLESTEROL
- 20ALPHA-HYDROXYCHOLESTEROL
- 20[S]-HYDROXYCHOLESTEROL
- 3BETA,20ALPHA-DIHYDROXY-5-CHOLESTENE
- 5-CHOLESTENE-3B,20ALPHA-DIOL
- 5-CHOLESTENE-3BETA,20ALPHA-DIOL
- 5-CHOLESTEN-3-BETA, 20-ALPHA-DIOL
- 20-hydroxycholesterol
- (3S,8S,9S,10R,13S,14S,17S)-17-((S)-2-hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
- 20(S)-hydroxyCholesterol (20α-Hydroxycholesterol)
- Cholest-5-ene-3,20-diol, (3β)-
- 20α-Hydroxy Cholesterol
- Cholesterol Impurity 32
- (8S,9S,10R,13S,14S,17S)-17-((R)-2-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
- 5-CHOLESTEN-3β, 20α-DIOL
- 516-72-3
- HU - HZ
- Alphabetic
- Analytical Standards
- Analytical Chromatography Product Catalog
- Intermediates & Fine Chemicals
- Metabolites & Impurities
- Pharmaceuticals
- Steroids
- Standards - 13C & 2H for GC-Mass Spectrometry
