成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

4-Amino-3-phenylbuttersure

Phenibut Struktur
1078-21-3
CAS-Nr.
1078-21-3
Bezeichnung:
4-Amino-3-phenylbuttersure
Englisch Name:
Phenibut
Synonyma:
Phenibut HCL;4-AMINO-3-PHENYLBUTYRIC ACID HCL;4-AMINO-3-PHENYLBUTANOIC ACID HYDROCHLORIDE;FENIBUT;Phenybut;Phenibut Powder;fenigam;phenylgam;Aminophenylbutyric acid;4-AMINO-3-PHENYLBUTIRIC ACID
CBNumber:
CB2316925
Summenformel:
C10H13NO2
Molgewicht:
179.22
MOL-Datei:
1078-21-3.mol

4-Amino-3-phenylbuttersure Eigenschaften

Schmelzpunkt:
252.5°C (rough estimate)
Siedepunkt:
311.75°C (rough estimate)
Dichte
1.1248 (rough estimate)
Brechungsindex
1.5710 (estimate)
L?slichkeit
Free base: 35 mg/mL in DMSO (195.29 mM) at 25 °C (SellekChem, 2019).Hydrochloride salt (Cayman, 2016): 25 mg/ml in DMF; 20 mg/ml in DMSO; 14 mg/ml in ethanol; 10 mg/mL in PBS (pH 7.2).
pka
4.10±0.10(Predicted)
Aggregatzustand
solid
Farbe
White
InChI
InChI=1S/C10H13NO2/c11-7-9(6-10(12)13)8-4-2-1-3-5-8/h1-5,9H,6-7,11H2,(H,12,13)
InChIKey
DAFOCGYVTAOKAJ-UHFFFAOYSA-N
SMILES
C(O)(=O)CC(C1=CC=CC=C1)CN
CAS Datenbank
1078-21-3(CAS DataBase Reference)
EPA chemische Informationen
Benzenepropanoic acid, .beta.-(aminomethyl)- (1078-21-3)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xi
HazardClass  IRRITANT
HS Code  2922498590
Toxizit?t TDLo orl-hmn: 5 mg/kg:CNS BEXBAN 57,52,64
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P302+P352 BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

4-Amino-3-phenylbuttersure Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Phenibut, also known as fenibut, phenigamma, and beta-phenyl-gamma-aminobutyric acid, is a derivative of the neurotransmitter GABA. It was developed in Russia,and there it has been used clinically since the 1960s to treat anxiety and related conditions,including insomnia(Lapin,2001). Phenibut has anxiolytic properties and is commonlycompared to benzodiazepines and baclofen.Structurally,phenibut issimilar to GABA, with the addition of the phenyl ring. This allows thecompound to more easily cross the blood-brain barrier, but also changesits activity profile (Shulgina,1986). Scientific studies demonstrate that phenibut can be safely used to treat anxiety, depression,epilepsy, speech disorders, and insomnia.

Verwenden

4-amino-3-phenylbutanoic acid (cas# 1078-21-3) is a GABAA receptor agonist, used for treatment of disorders influenced by dysfunction of pancreatic β cells and also used in combination with other agents.

synthetische

Phenibut was synthesized by Perekalin and his associates at the Department of Organic Chemistry of the Herzen Pedagogic Institute in St. Petersburg, the Russian Federation. In initial publications phenibut was known as phenigamma (Lapin, 2001, V. V. Perekalin, 1954).
Fenibut synthesis: from benzoyl chloride and ethyl acetoacetate as raw materials, through condensation and hydrolysis of ethyl benzoyl acetate, and then condensation of benzaldehyde and nitromethane to generate trans-nitrostyrene, and then the two are combined. Micheal addition, the adduct is then catalytically hydrogenated with Raney nickel, and finally hydrolyzed in concentrated hydrochloric acid to produce phenibate.
Synthesis of Phenibut (16) and Baclofen (17)
Synthesis of Phenibut (16) and Baclofen (17).

Application

Phenibut is an anxiolytic and nootropic drug, discovered in the Soviet Union used to treat several psychiatric disorders. It can be used in the treatment of anxiety, depression, asthenia, post-traumatic stress disorder, stuttering, and vestibular disorders.

Nebenwirkungen

When taken by mouth: Phenibut is likely unsafe. Phenibut can cause many side effects, including reduced consciousness, dizziness, nausea, poor balance, and fatigue. Taking large doses can cause trouble breathing, unconsciousness, and death.
Phenibut can cause dependence. People who use phenibut for 3 days or more and then stop taking it might experience withdrawal symptoms. These symptoms can include decreased appetite, nausea, muscle aches, fast heart rate, anxiety, agitation, trouble sleeping, and seizures.

Sicherheitsprofil

Moderately toxic by intraperitoneal route. Human systemic effects by ingestion: somnolence, hallucinations, distorted perception. Used as a mood elevator and tranquilizer. When heated to decomposition it emits toxic fumes of NOx.

Regulatory Status

USA - Phenibut is still an uncontrolled substance in the United States, and it is legal to sell and possess phenibut. It has not been approved for clinical use in the United States.
Europe - Unscheduled. It is not regulated by the European Medicines Agency. However, some nootropic substances such as piracetam are available only on prescription in some European Union countries and are freely available in others.
Russia - Phenibut is a licensed prescription medication used for a variety of conditions including anxiety, insomnia, post-traumatic stress disorders, depression, stuttering, tics, attention deficit disorders, and vestibular disorders. Russian cosmonauts were reported to have been supplied with the substance to help relieve tension, anxiety and fear (Buckley 2006).

4-Amino-3-phenylbuttersure Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


4-Amino-3-phenylbuttersure Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 385)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shaanxi Xianhe Biotech Co., Ltd
+8617709210191
Jerry@xhobio.com China 882 58
Guangzhou TongYi biochemistry technology Co.,LTD
+8613073028829
mack@tongyon.com China 2994 58
Baoji Guokang Bio-Technology Co., Ltd.
0917-3909592 13892490616
gksales1@gk-bio.com China 9312 58
Wuhan senwayer century chemical Co.,Ltd
+undefined-27-86652399 +undefined13627115097
market02@senwayer.com China 904 58
Shanghai Likang New Materials Co., Limited
+86-16631818819 +86-17736933208
3684455296@qq.com China 9300 58
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
+8615350851019
admin@86-ss.com China 1001 58
Hebei Lingding Biotechnology Co., Ltd.
+86-18031140164 +86-19933155420
erin@hbldbiotech.com China 58 58
Guangdong Junhua Chemical Co., Ltd
+86-075785239927 +86-13326778444
aron@hjococ.com China 35 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-81148696 +86-15536356810
1022@dideu.com China 3882 58
Dorne Chemical Technology co. LTD
+86-86-13583358881 +8618560316533
Ethan@dornechem.com China 3096 58

1078-21-3(4-Amino-3-phenylbuttersure)Verwandte Suche:


  • NA###4-Amino-3-phenylbutyric acid hydrochloride
  • TIMTEC-BB SBB001567
  • PHENIBUT
  • fenigama
  • pgaba
  • phenigam
  • phenigama
  • phenylgamma
  • AMINOBUTYRIC ACID, beta-PHENYL-gaMMa-(P)
  • Phenygam
  • 4-azanyl-3-phenyl-butanoic acid
  • (4-hydroxy-4-keto-2-phenyl-butyl)ammonium chloride
  • (4-hydroxy-4-oxo-2-phenylbutyl)ammonium chloride
  • (4-hydroxy-4-oxo-2-phenyl-butyl)ammonium chloride
  • (4-hydroxy-4-oxo-2-phenylbutyl)azanium chloride
  • (4-hydroxy-4-oxo-2-phenyl-butyl)azanium chloride
  • HYDROCINNAMIC ACID, beta-(AMINOMETHYL)-, HYDROCHLORIDE
  • 4-amino-3-phenylbutanoicacid
  • 4-amino-3-phenyl-butyricaci
  • beta-(aminomethyl)-benzenepropanoicaci
  • beta-(aminomethyl)benzenepropanoicacid
  • beta-(aminomethyl)hydrocinnamicacid
  • beta-phenyl-gamma-aminobutyrate
  • beta-phenyl-gamma-aminobutyricacid
  • 4-AMINO-3-PHENYL-BUTYRIC ACID
  • 4-AMINO-3-PHENYL BUTYRIC ACID HYDROCHLORIDE
  • 4-Amino-3-pheny-butyric acid
  • 4-Amino-3-phenyl
  • 4-AMINO-3-PHENY-BUTYRICACIDHYDROCHLORIDE
  • PHENYLBUT (4-AMINO-3-PHENYLBUTYRIC ACID HCL)
  • 3-PHENYL-4-AMINOBUTYRICACIDHCL
  • 4-Amino-3-phenylbutyric acid hydrchloride
  • B-(Aminomethyl)-benzenepropionic acid hydrochloride
  • Phenibut (4-AMino-3-phenylbutyric acid HCl)
  • Benzenepropanoic acid, b-(aMinoMethyl)-
  • Benzenepropanoic acid, .beta.-(aminomethyl)-
  • PHENIBUT
  • PHENIBUTCAS NO.: 1078-21-3 Phenibut CAS NO.1078-21-3
  • Nootropics Powder Nutrition Supplement Phenibut for Fatigue Reduce CAS 1078-21-3
  • Phenibut 4-Amino-3-Phenylbutyric Acid
  • 4-Amino-3-phenylbutanoic acid Hydrochloride, Phenibut
  • PhGABA
  • β-Phenyl-γ-aminobutyric acid
  • butyric Acid HydrochL
  • Benzenepropanoic acid, β-(aminomethyl)-
  • Phenibut Company Standards
  • Phenibut HCl Powder
  • 4-Amino-3-phenylbutanoic acid USP/EP/BP
  • Phenibut, 4-Amino-3-phenylbutanoic acid
  • Fenibut Phenibut
  • Hot Sale Phenibut Powder 99% Phenibut/Phenibut HCl CAS?1078-21-3
  • 4-Amino-3-Phenylbutanoic Acid/Phenibut
  • 4-AMINO-3-PHENYLBUTANOIC ACID HYDROCHLORIDE
  • 4-AMINO-3-PHENYLBUTIRIC ACID
  • -Amino-3-phenylbutyric acid hydrochloride
  • FENIBUT
  • Phenybut
  • fenigam
Copyright 2019 ? ChemicalBook. All rights reserved