成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

PLX3397 (Pexidartinib)

PLX3397 (Pexidartinib) Struktur
1029044-16-3
CAS-Nr.
1029044-16-3
Englisch Name:
PLX3397 (Pexidartinib)
Synonyma:
Pexidartinib;Turalio;PLX-3397;Pexidartinib (PLX3397);[5-(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-pyridin-2-yl]-(6-trifluoromethyl-pyridin-3-ylmethyl)-amine;PLX339;CML261;FP113);CS-1695;Peridartinib
CBNumber:
CB22742977
Summenformel:
C20H15ClF3N5
Molgewicht:
417.81
MOL-Datei:
1029044-16-3.mol

PLX3397 (Pexidartinib) Eigenschaften

Dichte
1.458±0.06 g/cm3(Predicted)
storage temp. 
-20°C
L?slichkeit
Soluble in DMSO (up to at least 10 mg/ml)
pka
12.81±0.40(Predicted)
Aggregatzustand
solid
Farbe
White
Stabilit?t:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
CAS Datenbank
1029044-16-3
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

PLX3397 (Pexidartinib) Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Colony stimulating factor 1 (CSF1) is a cytokine that is involved in the recruitment and activation of tissue macrophages. It exerts these effects by binding to its corresponding receptor tyrosine kinase, the cFMS/CSF1 receptor (CSF1R). Pexidartinib is a brain-penetrant inhibitor of CSF1R, as well as c-Kit and FLT3 (IC50s = 20, 10, and 160 nM in vitro, respectively). It has been used in combination with paclitaxel to block macrophage recruitment in mammary tumor-bearing mice, thus slowing primary tumor development and metastasis. Pexidartinib has also been used to block microglial stimulation of glioblastoma invasion in both cell culture and a mouse model of glioblastoma multiforme.

Verwenden

Pexidartinib is RTK inhibitor. It can be used in pharmacological activity, therapeutic use, and biological study of inhibition of colony stimulating factor-1 receptor improves antitumor efficacy of BRAF inhibition.

Trademarks

Turalio

PLX3397 (Pexidartinib) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

PLX3397 (Pexidartinib) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 157)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hangzhou FandaChem Co.,Ltd. 		+8615858145714
 FandaChem@Gmail.com China 9087 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32957 60
Biochempartner 		0086-13720134139
candy@biochempartner.com CHINA 965 58
BOC Sciences 		+1-631-485-4226
inquiry@bocsci.com United States 19553 58
TopScience Biochemical 		00852-68527855
info@itopbiochem.com China Hong Kong 902 58
career henan chemical co 		+86-0371-86658258 +8613203830695
 factory@coreychem.com China 29811 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226
 sales@hzclap.com CHINA 6312 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250
 1026@dideu.com China 22784 58
Chemia Biotechnology（Shanghai） Co., Ltd 		+8613816753574
 info@chemia-pharm.com CHINA 311 58

1029044-16-3()Verwandte Suche:

  • 5-((5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl)-N-((6-(trifluoromethyl)pyridin-3-yl)methyl)
  • 3-Pyridinemethanamine,N-[5-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-2-pyridinyl]-6-(trifluoromethyl)-
  • N-[5-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-2-pyridinyl]-6-(trifluoromethyl)-3-pyridinemethanamine
  • PLX3397 (Pexidartinib)
  • PLX339
  • 5-((5-chloro-1H-pyrrolo[2,3-b]pyridin-2-yl)methyl)-N-((6-(trifluoromethyl)pyridin-3-yl)methyl)pyridin-2-amine
  • 5-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-N-[[6-(trifluoromethyl)pyridin-3-yl]methyl]pyridin-2-amine
  • CS-1695
  • PLX3397;PLX 3397;PLX-3397
  • PLX3397 (Pexidartinib) USP/EP/BP
  • Peridartinib
  • CML261
  • FP113)
  • PLX-3397
  • Pexidartinib (PLX3397)
  • Pexidartinib
  • [5-(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-pyridin-2-yl]-(6-trifluoromethyl-pyridin-3-ylmethyl)-amine
  • Turalio
  • 13C,2H4]-Peridartinib
  • PLX3397,inhibit,PLX 3397,CSF-1 receptor,SCFR,Pexidartinib,Inhibitor,c-Fms,Apoptosis,CSF-1R,colony stimulating factor 1 receptor,CSF1R,CD117,c-Kit
  • 5-[[5-Chloropyrrolo[2,3-b]pyridin-3-yl]methyl]-2-[[[6-(trifluoromethyl)-3-pyridyl]methyl]amino]pyridine
  • Morinidazole Impurity 14
  • 1-(5-methyl-2-nitro-1H-imidazol-1-yl)-3-morpholinopropan-2-ol
  • 1029044-16-3
  • 1029004-16-3
  • C20H15ClF3N5
  • Inhibitors
  • API
Copyright 2019 ? ChemicalBook. All rights reserved