6-Aminopenicillansure
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- CAS-Nr.
- 551-16-6
- Bezeichnung:
- 6-Aminopenicillansure
- Englisch Name:
- 6-Aminopenicillanic acid
- Synonyma:
- 6-APA;6-amino penicillanic acid(6-APA);6-Amino;Flucloxacillin EP Impurity C;AMoxicillin Related CoMpound A;6-AMINO-2,2-DIMETHYL-5-OXOPERHYDROAZETO[2,1-B][1,3]THIAZOLE-3-CARBOXYLIC ACID;Amoxicillin Related Compound A (15 mg) ((2S,5R,6R)-6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid);penin;6-aps;penicin
- CBNumber:
- CB1410046
- Summenformel:
- C8H12N2O3S
- Molgewicht:
- 216.26
- MOL-Datei:
- 551-16-6.mol
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6-Aminopenicillansure Eigenschaften
- Schmelzpunkt:
- 198-200 °C (dec.)(lit.)
- Siedepunkt:
- 460.2±45.0 °C(Predicted)
- alpha
- 276.3 º (c=1.2, 0.1N HCl 22 ºC)
- Dichte
- 1.3418 (rough estimate)
- Brechungsindex
- 1.6300 (estimate)
- storage temp.
- 2-8°C
- L?slichkeit
- 2.46g/l
- Aggregatzustand
- Fine Powder
- pka
- pKa 2.3 (Uncertain)
- Farbe
- White to cream
- PH
- 3.4 (100g/l, H2O)
- Optische Aktivit?t
- [α]22/D +276.3°, c = 1.2 in 0.1 M HCl
- Wasserl?slichkeit
- Soluble in water and hydrochoric acid.
- Merck
- 14,458
- BRN
- 15080
- Stabilit?t:
- Light sensitive
- InChIKey
- NGHVIOIJCVXTGV-SDKNWNMFSA-N
- LogP
- -3.87 at 22.5℃
- CAS Datenbank
- 551-16-6(CAS DataBase Reference)
- EPA chemische Informationen
- 6-Aminopenicillanic acid (551-16-6)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
| P337+P313 |
Bei anhaltender Augenreizung: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen. |
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6-Aminopenicillansure Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R42/43:Sensibilisierung durch Einatmen und Hautkontakt m?glich.
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
S37:Geeignete Schutzhandschuhe tragen.
S24:Berührung mit der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
WHITE TO CREAM FINE POWDER
Verwenden
(+)-6-Aminopenicillanic Acid is the core structure in penicillins, obtained from the fermentation brew of the Penicillium mold. (+)-6-Aminopenicillanic Acid is used as the main starting block for the
preparation of numerous semisynthetic penicillins.
Definition
ChEBI: A penicillanic acid compound having a (6R)-amino substituent. The active nucleus common to all penicillins, it may be substituted at the 6-amino position to form the semisynthetic penicillins, resulting in a variety of antibacterial and ph
rmacologic characteristics.
Allgemeine Beschreibung
Chemical structure: ?-lactam
Sicherheitsprofil
Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits very toxic fumes of NOx and SOx.
l?uterung methode
This acid crystallises from water. [Kleppe & Stroninger J Biol Chem 254 4856 1979,Beilstein 27 III/IV 2858.]
6-Aminopenicillansure Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
[2S-[2α,5α,6β(S*)]]-6-[[[[(4-Ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptan-2-carbonsure
Carbenicillin
6-(2-Phenylacetamido)penicillansure
Imipenem
Oxacillin sodium monohydrate
Natrium-[2S-(2α,5α,6β)]-6-[[[3-(2-chlor-6-fluorphenyl)-5-methylisoxazol-4-yl]carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptan-2-carboxylat
[2S-(2α,5α,6α)]-6-Brom-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptan-2-carbonsure
(2S-cis)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptan-2-carbonsure
(3S)-6,6-DIBROMO-2,2-DIMETHYLPENAM-3-CARBOXYLIC ACID 1,1-DIOXIDE
Meticillin
4-Thiazolecarboxylic acid
6β-Phthalimidopenicillanic Acid
6-Aminopenicillansure Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 529)Lieferanten
| Firmenname |
Telefon |
E-Mail |
Land |
Produktkatalog |
Edge Rate |
|
Hebei Weibang Biotechnology Co., Ltd
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+8615531157085
|
abby@weibangbio.com |
China |
8810 |
58 |
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Hebei Mojin Biotechnology Co., Ltd
|
+86 13288715578 +8613288715578
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sales@hbmojin.com |
China |
12835 |
58 |
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Hebei Yanxi Chemical Co., Ltd.
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+8617531190177
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peter@yan-xi.com |
China |
5857 |
58 |
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Hebei Chuanghai Biotechnology Co,.LTD
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+86-13131129325
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sales1@chuanghaibio.com |
China |
5889 |
58 |
|
Hebei Weibang Biotechnology Co., Ltd
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+8617732866630
|
bess@weibangbio.com |
China |
18151 |
58 |
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Hangzhou ICH Biofarm Co., Ltd
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+86-0571-28186870; +undefined8613073685410
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sales@ichemie.com |
China |
1001 |
58 |
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airuikechemical co., ltd.
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+undefined86-15315557071
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sales02@sdzhonghuimaterial.com |
China |
983 |
58 |
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Hebei Ganmiao New material Technology Co., LTD
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+86-17332992504 +86-17332992504
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sales8@hbganmiao.com |
China |
300 |
58 |
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BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
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+86-18600796368 +86-18600796368
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sales@sjar-tech.com |
China |
456 |
58 |
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Henan Tianfu Chemical Co.,Ltd.
|
+86-0371-55170693 +86-19937530512
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info@tianfuchem.com |
China |
21634 |
55 |
551-16-6(6-Aminopenicillansure)Verwandte Suche:
- 6-AMINO-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID
- (+)-6-AMINOPENICILLANIC ACID
- 6-AMINOPENICILLANIC ACID
- 6-AMINO PENICILLINIC ACID
- 7-AMINO-3,3-DIMETHYL-6-OXO-2-THIA-5-AZABICYCLO[3.2.0]HEPTANE-4-CARBOXYLIC ACID
- (25,5R,6R)-6-AMINO-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID
- (2S,5R,6R)-6-AMINO-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO-[3.2.0]HEPTANE-2-CARBOXYLIC ACID
- aminopenicillanicacid
- penicin
- penin
- phenacyl6-aminopenicillinate
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-amino-3,3-dimethyl-7-oxo-, [2S-(2alpha,5alpha,6beta)]-
- 6-Aminopenicillanic acid;6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; 6-APA
- 6-Aminopenicillanicacid,98%
- 6-Amino-2,2-dimethyl-5-oxoperhydroazeto[2,1-b][1,3]thiazole-3-carboxylic acid 98%
- 6-Aminopenicillansure
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-amino-3,3-dimethyl-7-oxo-,[2S-(2.alpha.,5.alpha.,6.beta.)]
- 6-AMINOPENICILLANIC ACID 99%
- (2S,5R,6R)-6-Amino-2,2-dimethyl-5-oxoperhydroazeto[2,1-b][1,3]thiazole-3-carboxylic acid 98%
- (2S,5R,6R)-6-Amino-2,2-dimethyl-5-oxoperhydroazeto[2,1-b][1,3]thiazole-3-carboxylic acid
- AMoxicillin IMpurity A (SulbactaM IMpurity B)
- Piperacillin IMpurity H
- Amoxicillin EP Impurity A
- (+)-6-Aminopenicillanic acid, >=99.0%
- Penicillan intermediate: penicillan core
- 6-Aminopenicillanic acid for synthesis
- (2S,5R,6R)-6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
6-APA
6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
6-amino-2,2-dimethyl-5-oxoperhydroazeto[2,1-b][1
- 4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,6-amino-3,3-dimethyl-7-oxo
- 5alpha,6beta)]-[2s-(2alpha
- 6-amino-3,3-dimethyl-7-oxo-,[2S-(2.alpha.,5.alpha.,6.beta.)]-4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid
- 6-aps
- 6-APA, (2S,5R,6R)-6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-amino-3,3-dimethyl-7-oxo-, (2S,5R,6R)-
- (2S,5β)-6α-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2β-carboxylic acid
- (2β,5β)-6α-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2β-carboxylic acid
- (6R)-6-Aminopenicillanic acid
- 6-Aminopenicillanic acid,96%
- 6-AMinopenicillanic acid, 96% 25GR
- [2S-(2α,5α,6β)]-6-AMino-3,3-diMethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid
- NSC 50071
- 4-AMino-5-nitroso-2,6-pyriMidinediol-13C2
- 5-Nitroso-6-aMinouracil-13C2
- 6-AMino-5-nitroso-2,4(1H,3H)-pyriMidinedione-13C2
- 6-AMino-5-nitroso-2,4-pyriMidinediol-13C2
- 6-AMino-5-nitroso-22,4(1H,3H)-pyriMidinedione-13C2
- 6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid
6-APA
- 6-amino-2,2-dimethyl-5-oxoperhydroazeto[2,1-b][1
- (+)-6-Aminopenicillanic acid,(2S,5R,6R)-6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-APA
- (2S,5R,6R)-6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid (6-Aminopenicillanic Acid)
- SulbactaM IMpurity B (AMoxicillin IMpurity A)
- Amoxicillin EP Impurity A(Sulbactam EP Impurity B)
- Sulbactam impurity B
- 6-aminopenicilanic acid(6-APA)
- Cloxacillin Impurity 3(Cloxacillin EP Impurity C)
- Dicloxacillin Impurity 3(Dicloxacillin EP Impurity C)
- Flucloxacillin Impurity 3(Flucloxacillin EP Impurity C)
- Piperacillin Impurity 8(EP Impurity H)
- Sulbactam Impurity 2(Sulbactam EP Impurity B)
