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(5α)-17-Allyl-4,5-epoxy-3,14-dihydroxymorphinan-6-onhydrochlorid

Naloxone hydrochloride  Struktur
357-08-4
CAS-Nr.
357-08-4
Bezeichnung:
(5α)-17-Allyl-4,5-epoxy-3,14-dihydroxymorphinan-6-onhydrochlorid
Englisch Name:
Naloxone hydrochloride
Synonyma:
NALOXONE HCL;narcan;en1530;Nalone;nalonee;nih7890;EN-15304;Narcanti;Naloxone hydrochlori;NALOXONE HYDROCHLORIDE
CBNumber:
CB1409273
Summenformel:
C19H22ClNO4
Molgewicht:
363.84
MOL-Datei:
357-08-4.mol

(5α)-17-Allyl-4,5-epoxy-3,14-dihydroxymorphinan-6-onhydrochlorid Eigenschaften

Schmelzpunkt:
200-2050C
RTECS-Nr.
QD2275000
storage temp. 
2-8°C
L?slichkeit
ethanol: 3.3 mg/mL stable for several months refrigerated if protected from light.
Aggregatzustand
powder
Farbe
white to off-white
Wasserl?slichkeit
Soluble in water (73 mg/ml), ethanol (3.3 mg/ml), methanol (50 mg/ml) and dimethyl sulfoxide (73 mg/ml). Insoluble in ether
Stabilit?t:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 2 months.
CAS Datenbank
357-08-4(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xi
R-S?tze: 36/37/38
S-S?tze: 22-24/25-26-36/37/39-36
WGK Germany  3
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P304+P340 BEI EINATMEN: Die Person an die frische Luft bringen und für ungehinderte Atmung sorgen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.
P405 Unter Verschluss aufbewahren.

(5α)-17-Allyl-4,5-epoxy-3,14-dihydroxymorphinan-6-onhydrochlorid Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-S?tze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.

Beschreibung

Naloxone (hydrochloride) (CRM) (Item No. ISO60191) is a certified reference material categorized as an opioid antagonist. Formulations containing naloxone have been used as antidotes for opioid overdose and the prevention of overdose. They have also been used in combination with buprenorphine (Item Nos. ISO60178 | 14025) in the treatment of opiate addiction and in pain management. This product is intended for research and forensic applications.

Chemische Eigenschaften

Crystalline Solid

Verwenden

Naloxone Hydrochloride is a specific opioid antagonist. Narcotic antagonist.

Definition

ChEBI: A hydrochloride resulting from the formal reaction of equimolar amounts of naloxone and hydrogen chloride. A specific opioid antagonist, it is used to reverse the effects of opioids, both following their use of opioids during surgery and in cases of known r suspected opioid overdose.

Biologische Aktivit?t

Opioid antagonist.

(5α)-17-Allyl-4,5-epoxy-3,14-dihydroxymorphinan-6-onhydrochlorid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


(5α)-17-Allyl-4,5-epoxy-3,14-dihydroxymorphinan-6-onhydrochlorid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 263)Lieferanten
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Guangzhou Tengyue Chemical Co., Ltd.
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Antai Fine Chemical Technology Co.,Limited
18503026267
info@antaichem.com CHINA 9636 58

357-08-4((5α)-17-Allyl-4,5-epoxy-3,14-dihydroxymorphinan-6-onhydrochlorid)Verwandte Suche:


  • NALOXONE HYDROCHLORIDE
  • (5ALPHA)-4,5-EPOXY-3,14-DIHYDRO-17-(2-PROPENYL)MORPHINAN-6-ONE HYDROCHLORIDE
  • 17-allyl-4,5-alpha-epoxy-3,14-dihydroxymorphinan-6-onehydrochloride
  • 4,5alpha-epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-one hydrochloride
  • en1530
  • l-n-allyl-14-hydroxynordihydromorphinonehydrochloride
  • morphinan-6-one,4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)-,hydrochloride,(5-a
  • nalonee
  • 17-allyl-4,5-alpha-epoxy-3,14-dihydroxy-morphinan-6-onhydrochloride
  • (5α)-4,5-Epoxy-3,14-dihydroxy-17-(2-propenyl)Morphinan-6-one Hydrochloride
  • 17-Allyl-4,5α-epoxy-3,14-dihydroxyMorphinan-6-one Hydrochloride
  • Morphinan-6-one,4,5-epoxy-3,14-dihydroxy-17-(2-propen-1-yl)-, hydrochloride (1:1), (5a)-
  • 17-Allyl-3,14-dihydroxy-4,5alpha-epoxyMorphinan-6-one hydrochloride
  • Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-(2-propen-1-yl)-, hydrochloride (1:1), (5α)-
  • nih7890
  • (5alpha)-17-allyl-4,5-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride
  • NALOXONE HYDROCHLORIDE OPIOID ANTAGONIST
  • NALOXONE HYDROCHLORIDE CRYSTALLINE
  • (5a)-4,5-Epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-one Hydrochloride
  • 17-Allyl-4,5a-epoxy-3,14-dihydroxymorphinan-6-one Hydrochloride
  • EN-15304
  • Nalone
  • Narcanti
  • Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)-, hydrochloride, (5.alpha.)-
  • (-)-N-Allyl-14-hydroxynordihydromorphinone hydrochloride
  • l-Naloxone hydrochloride
  • Morphinan-6-one, 17-allyl-4,5a-epoxy-3,14-dihydroxy-, hydrochloride (8CI)
  • Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)-, hydrochloride, (5a)- (9CI)
  • N-Allyldihydro-14-hydroxynormorphinone hydrochloride
  • Normorphinone, N-allyl-7,8-dihydro-14-hydroxy-, hydrochloride (7CI)
  • (5alpha)-4,5-Epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-one hydrochloride
  • (5α)-4,5-Epoxy-3,14-dihydro-17-(2-propenyl)morphinan-6-onehydrochloride
  • Naloxone hydrochloride (controlled)
  • Naloxone (hydrochloride) (CRM)
  • Naloxone hydrochloride USP/EP/BP
  • Naloxone hydrochlori
  • NALOXONE HCL
  • narcan
  • Naloxone Hydrochloride hydrate
  • Naloxone hydrochloride in methanol
  • 357-08-4
  • C19H21NO4HClH2O
  • C19H21NO4HCl
  • C19H22ClNO4
  • C19H21NO4HClC19H22ClNO4
  • API
  • Chiral Reagents
  • Drug Analogues
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Opioid receptor and opioid-like receptor
  • Opioids
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