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N-(Hydroxymethyl)phthalimide

N-(Hydroxymethyl)phthalimide Struktur
118-29-6
CAS-Nr.
118-29-6
Englisch Name:
N-(Hydroxymethyl)phthalimide
Synonyma:
AURORA KA-454;N-(HydroxymethyL;AKOS BBS-00004724;IFLAB-BB F0777-0575;PHTHALIMIDOMETHANOL;N-(Hydroxymethyl)ph;oxymethylphthalimide;Phthalimidylmethanol;N-Methylolphthalimide;Oxymethyl phthalimide
CBNumber:
CB1392676
Summenformel:
C9H7NO3
Molgewicht:
177.16
MOL-Datei:
118-29-6.mol

N-(Hydroxymethyl)phthalimide Eigenschaften

Schmelzpunkt:
147-149 °C (lit.)
Siedepunkt:
309.06°C (rough estimate)
Dichte
1.3312 (rough estimate)
Brechungsindex
1.5200 (estimate)
storage temp. 
Store below +30°C.
pka
13.17±0.10(Predicted)
Aggregatzustand
Fine Crystalline Powder
Farbe
White
BRN 
140946
InChIKey
MNSGOOCAMMSKGI-UHFFFAOYSA-N
CAS Datenbank
118-29-6(CAS DataBase Reference)
NIST chemische Informationen
1H-isoindole-1,3(2h)-dione, 2-(hydroxymethyl)-(118-29-6)
EPA chemische Informationen
N-(Hydroxymethyl)phthalimide (118-29-6)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
S-S?tze: 22-24/25
WGK Germany  3
RTECS-Nr. TI5270000
TSCA  Yes
HS Code  29251995
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P304+P340 BEI EINATMEN: Die Person an die frische Luft bringen und für ungehinderte Atmung sorgen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.
P405 Unter Verschluss aufbewahren.

N-(Hydroxymethyl)phthalimide Chemische Eigenschaften,Einsatz,Produktion Methoden

S-S?tze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.

Chemische Eigenschaften

white crystalline powder

Verwenden

N-(Hydroxymethyl)phthalimide is used as a reactant in the synthesis of 5-[(3-aralkyl amido/imidoalkyl)phenyl]-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazines as antiviral agents.

Definition

ChEBI: A primary alcohol comprising phthalimide carrying an N-hydroxymethyl substituent.

synthetische

To a flask equipped with a mechanical stirrer and condenser is added 511 gm (3.47 moles) of phthalimide, 260 ml of 40% formalin (3.47 moles), and 1750 ml of water. The mixture is refluxed for about 5-10 min or until a clear solution results (if any insoluble material remains, it is first filtered). Then the mixture is cooled for several hours. The resulting product is filtered with suction, washed with cold water, and air-dried to afford 594 gm (96%), m.p. 137-141°C.
NOTE: The product should not be oven-dried since it decomposes with the loss of formaldehyde. Recrystallization of the product from ethanol affords 94% recovery of the original material with the same melting point range.
Preparation of N-Hydroxymethylphthalimide

N-(Hydroxymethyl)phthalimide Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


N-(Hydroxymethyl)phthalimide Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 400)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hebei Weibang Biotechnology Co., Ltd
+8615531157085
abby@weibangbio.com China 8810 58
Hebei Mojin Biotechnology Co., Ltd
+86 13288715578 +8613288715578
sales@hbmojin.com China 12835 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325
sales1@chuanghaibio.com China 5889 58
Zibo Hangyu Biotechnology Development Co., Ltd
+86-0533-2185556 +8617865335152
Mandy@hangyubiotech.com China 10986 58
Shaanxi TNJONE Pharmaceutical Co., Ltd
+8618092446649
sarah@tnjone.com China 1143 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806
sales@capot.com China 29791 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886
info@dakenam.com China 18751 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21634 55
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29880 58
Hubei Jusheng Technology Co.,Ltd.
18871490254
linda@hubeijusheng.com CHINA 28172 58

118-29-6()Verwandte Suche:


  • 2-methylolisoindoline-1,3-quinone
  • PHTHALIMIDOMETHANOL
  • N-(HYDROXYMETHYL)PHTHALIMIDE
  • HYDROXYMETHYL PHTHALIMIDE
  • IFLAB-BB F0777-0575
  • AURORA KA-454
  • 2-(hydroxymethyl)-1h-isoindole-3(2h)-dione
  • 2-Hydroxymethyl-isoindole-1,3-dione
  • Methanol, phthalimido-
  • n-(hydroxymethyl)-phthalimid
  • N-Methylolphthalimide
  • Oxymethyl phthalimide
  • AKOS BBS-00004724
  • 2-(HYDROXYMETHYL)-1H-ISOINDOLE-1,3(2H)-DIONE
  • oxymethylphthalimide
  • Phthalimide, N-(hydroxymethyl)-
  • Phthalimidomethyl alcohol
  • phthalimidomethylalcohol
  • 4-(Hydroxymethyl)phthalimide, 97%
  • 1H-Isoindole-1,3(2H)-dione, 2-(hydroxymethyl)-
  • N-Hydroxymethylphthalimide, 97 %
  • N-(Hydroxymethyl)phthalimide, 98+%
  • 2-(Hydroxymethyl)-1,3-dihydro-2H-isoindole-1,3-dione
  • 2-(Hydroxymethyl)isoindoline-1,3-dione
  • Phthalimidylmethanol
  • N-(Hydroxymethyl)phthalimide,Phthalimidomethanol
  • N-(Hydroxymethyl)ph
  • 2-(hydroxymethyl)-1,3-isoindolinedione
  • 2-(Hydroxymethyl)-1H-isoindole-1,3(2H)-dione, (Phthalimid-1-yl)methanol
  • N-(HydroxyMrthyl)phthaliMide
  • N-(HYDROXYMETHYL)-PHTHALIMIDE FOR SYNTHE
  • N- hydroxyMethyladjacent benzenetwoMethyl iMide
  • N - hydroxy Methyl phthalates forMyl iMine
  • N-Hydroxymethylphthalimide
  • 2-(Hydroxymethyl)-1H-isoindole-1,3(2H)-dione, 2-(Hydroxymethyl)isoindolin-1,3-dione
  • N-(HydroxymethyL
  • N-Hydroxymethylphthalimide>
  • N-Hydroxyl-Methyl phthalimide
  • 2-ACETYL-5-CHLORO-73-METHYLTHIANAPHTHENE
  • N-(-2-HYDROXYMETHYL) PHTHALIMIDE
  • 118-29-6
  • N-Substituted Maleimides, Succinimides & Phthalimides
  • N-Substituted Phthalimides
  • ALCOHOL
  • Organic Building Blocks
  • Cyclic Imides
  • Carbonyl Compounds
  • Building Blocks
  • N-Substituted Maleimides, Succinimides & Phthalimides
  • N-Substituted Phthalimides
  • intermediates
  • fine chemicals
  • pharmacetical
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