Hexapeptide-11 Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Hexapeptide-11 is a novel modulator of the proteostasis network in human diploid fibroblasts.
Verwenden
Hexapeptide-11 reduces the appearance of fine lines and wrinkles, making this an excellent addition to all kinds of skin care and anti-aging products. It has a unique set of amino acids that help to manipulate collagen levels and boost elasticity in the skin.
Physiological effects
Exposure of fibroblasts to Hexapeptide-11 promoted dose and time-dependent activation of proteasome, autophagy, chaperones and antioxidant responses related genes. Moreover, it promoted increased nuclear accumulation of Nrf2; higher expression levels of proteasomal protein subunits and increased proteasome peptidase activities. In line with these findings we noted that Hexapeptide-11 conferred significant protection in fibroblasts against oxidative-stress-mediated premature cellular senescence, while at in vivo skin deformation assays in human subjects it improved skin elasticity.
Hexapeptide-11 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte