Glutathion
|
|
|
- CAS-Nr.
- 70-18-8
- Bezeichnung:
- Glutathion
- Englisch Name:
- Glutathione
- Synonyma:
- GSH;L-GLUTATHIONE REDUCED;REDUCED GLUTATHIONE;Glutathion;glutatione;GLUTATHIONE REDUCED FORM;isethion;Glutathione powder;Atomolan;glutatiol
- CBNumber:
- CB6320803
- Summenformel:
- C10H17N3O6S
- Molgewicht:
- 307.32
- MOL-Datei:
- 70-18-8.mol
|
Glutathion Eigenschaften
- Schmelzpunkt:
- 192-195 °C (dec.) (lit.)
- Siedepunkt:
- 754.5±60.0 °C(Predicted)
- alpha
- -16.5 º (c=2, H2O)
- Dichte
- 1.4482 (rough estimate)
- Brechungsindex
- -17 ° (C=2, H2O)
- storage temp.
- 2-8°C
- L?slichkeit
- H2O: 50 mg/mL
- Aggregatzustand
- powder
- pka
- pK1 2.12; pK2 3.53; pK3 8.66; pK4 9.12(at 25℃)
- Farbe
- White
- PH
- 3 (10g/l, H2O, 20°C)
- Geruch (Odor)
- Odorless
- Optische Aktivit?t
- -21.327 (H2O)
- Wasserl?slichkeit
- soluble
- Merck
- 14,4475
- BRN
- 1729812
- Sequenz
- H-γ-Glu-Cys-Gly-OH
- Stabilit?t:
- Stable. Incompatible with strong oxidizing agents.
- InChIKey
- RWSXRVCMGQZWBV-WDSKDSINSA-N
- LogP
- -1.645 (est)
- CAS Datenbank
- 70-18-8(CAS DataBase Reference)
- EPA chemische Informationen
- Glutathione (70-18-8)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
|
| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
|
|
| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
|
Glutathion Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R68:Irreversibler Schaden m?glich.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S27:Beschmutzte, getr?nkte Kleidung sofort ausziehen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Beschreibung
Glutathione (GSH) is a tripeptide (γ-
glutamylcysteinylglycine) widely distributed in both plants and animals. GSH serves as a nucleophilic co-
substrate to glutathione transferases in the detoxification of xenobiotics and is an essential electron donor to glutathione peroxidases in the reduction of hydroperoxides. GSH is also involved in amino acid transport and maintenance of protein sulfhydryl reduction status. The concentration of GSH ranges from a few micromolar in plasma to several millimolar in tissues such as liver.
Chemische Eigenschaften
White cryst. powder
Definition
ChEBI: A tripeptide compound consisting of glutamic acid attached via its side chain to the N-terminus of cysteinylglycine.
Allgemeine Beschreibung
Glutathione (GSH) is the most important nonprotein thiol widely distributed in animal tissues, plants, and microorganisms. GSH is also a key determinant of redox signaling and protection against oxidative stress.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Sicherheitsprofil
Moderately toxic by
intravenous route. Experimental
reproductive effects. Human mutation data
reported. When heated to decomposition it
emits very toxic fumes of SOx and NOx.
l?uterung methode
Crystallise L-glutathione from 50% aqueous EtOH, dry it in a vacuum and
Glutathion Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Glutathion Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 1133)Lieferanten
70-18-8(Glutathion)Verwandte Suche:
- glutide
- glutinal
- l-glutatione
- N(N-L-.gamma.-Glutamyl-L-cysteinyl)glycine
- n-(n-l-gamma-glutamyl-l-cysteinyl)-glycin
- neuthion
- panaron
- tathion
- tathione
- triptide
- L-Glutathione reduced Vetec(TM) reagent grade, >=98%
- TWEEN 80 REAGENT GRADE
- glutathiose
- L-Glutathione Reduced(GSH)
- Gamma Glu-L-Cys-Gly-OH
- Glutathione(Reduced Form), free acid, Animal-Free
- γ-Glutamylcysteinylglycine
- GLYCINE,N-(N-GAMMA-GLUTAMYL-CYSTEINYL)-
- REDUCEDGLUTHATIONE
- GLUTATHIONE PHARMACEUTICAL GRADE
- L-GLUTATHIONE REDUCED ( INJECTABLE GRADE )
- L-GLUTATHIONE REDUCED ( ORAL GRADE )
- G1UTATHION
- L-.GLUTATHIONE (REDUCED) [N-(N-L-G-GLUTAMYL-L-CYSTEINYL)GLYCINE]
- Bakezyme RX
- GLUTAMYCYSTEINYLGLYCINE
- GLUTATHIONE REDUCED extrapure for
- 2-Amino-4-[[1-(carboxymethylcarbamoyl)-2-sulfanyl-ethyl]carbamoyl]butanoic acid
- Glutathione, 98%, reduced, for analysis
- Glutathione,98%,for analysis,reduced
- Glycine, N-(N-L-gamma-glutamyl-L-cysteinyl)-
- Glutathion，oxidation
- L-Glutathione ,99%
- L-GLUTATHIONE (REDUCED FORM)CRYST. RESEARCH GRADE
- L-Glutathione reduced,γ-L-Glutamyl-L-cysteinyl-glycine, GSH
- L-Glutathione ,99% [for analysis,reduced]
- Glutathione Readuced
- Glutathione (300 mg)
- lutathione, reduced Glutathione
- Glutathione USP
- L-Glutathione, for analysis, reduced
- (S)-2-AMino-5-(((R)-1-((carboxyMethyl)aMino)-3-Mercapto-1-oxopropan-2-yl)aMino)-5-oxopentanoic acid
- Glutathione reduced SynonyMs 5-L-GlutaMyl-L-cysteinylglycine
- Glutathione
5-L-Glutamyl-L-cysteinylglycine
- glutathione,r-glutamyl cysteingl +glycine
- 5-L-Glutamyl-L-cysteinylglycine
- γ-L-Glutamyl-L-cysteinyl-glycine
- gamma-L-Glutamyl-L-cysteinylglycine~GSH
- Glutathione reduced (GSH)
- Glutathione, Reduced, Free Acid
- GLUTATHIONE FREE ACID REDUCED FORM*CELL CULTURE TES
- GLUTATHIONE REDUCED FORM FREE ACID
- GLUTATHIONE FREE ACID REDUCED FORM*CRYSTALLINE
- GLUTATHIONE REDUCED FORM FREE ACID*SIGMA ULTRA
- L-Gluthathione
- Glutathione(Reduced)ForBiochemistry
- N-(N-L-γ-Glutamyl-L-cysteinyl)glycine
- Glutathione, reduced, for analysis, 98%
