Spectinomycin dihydrochloride pentahydrate
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- CAS-Nr.
- 22189-32-8
- Englisch Name:
- Spectinomycin dihydrochloride pentahydrate
- Synonyma:
- SPECTINOMYCIN HCL;SPECTINOMYCIN HYDROCHLORIDE;SPECTINOMYCIN PENTAHYDRATE DIHYDROCHLORIDE;M 141;D00869;U-18409AE;spectogard;Trobicin (tn);SPECTINOMYCIN 2HCL;Spectinomycin,≥98%
- CBNumber:
- CB1177273
- Summenformel:
- C14H27ClN2O8
- Molgewicht:
- 386.83
- MOL-Datei:
- 22189-32-8.mol
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Spectinomycin dihydrochloride pentahydrate Eigenschaften
- Schmelzpunkt:
- 205-207° (dec)
- alpha
- D +14.8° (c = 0.42 in water)
- storage temp.
- 2-8°C
- L?slichkeit
- H2O: 50 mg/mL, clear, faintly yellow
- Aggregatzustand
- powder
- Farbe
- white to off-white
- Wasserl?slichkeit
- Soluble in water.Soluble in water, methanol, dimethyl sulfoxide, ethanol and dimethyl formamide.
- Merck
- 14,8739
- BRN
- 5684150
- InChIKey
- DCHJOVNPPSBWHK-UXXUFHFZSA-N
- CAS Datenbank
- 22189-32-8
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| S-S?tze: |
24/25 |
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| WGK Germany |
2 |
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| RTECS-Nr. |
WG7400000 |
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| F |
10 |
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| HS Code |
29419090 |
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| Toxizit?t |
mouse,LD50,intramuscular,> 5gm/kg (5000mg/kg),BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY),Japanese Journal of Antibiotics. Vol. 29, Pg. 43, 1976. |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P271 |
Nur im Freien oder in gut belüfteten R?umen verwenden. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P302+P352 |
BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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Spectinomycin dihydrochloride pentahydrate Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Spectinomycin was found in the culture broth of Streptomyces spectabilis by Upjohn Co. in 1961. This antibiotic was intended for use in treating various infections, as are the other aminoglycoside antibiotics, but its activity is insufficient for clinical efficacy except against gonorrhea. Spectinomycin does not develop crossresistance with any other antibiotic and shows low toxicity; it is used by deep intramuscular injection for “single-session,” bolusinjection therapy of gonorrhea.
Chemische Eigenschaften
White or almost white, slightly hygroscopic powder.
Verwenden
Spectinomycin Dihydrochloride Pentahydrate is a new animal drug application (ANADA) administered in the drinking water of chickens as an aid in the control of airsacculitis; Also, it is an aminocylcitol antibiotic.
Definition
ChEBI: A hydrate that is the pentahydrate form of spectinomycin hydrochloride. An antibiotic that is active against gram-negative bacteria and used to treat gonorrhea.
Allgemeine Beschreibung
A broad spectrum aminoglycoside antibiotic that contains two glucose moieties. Footprint studies indicate that spectinomycin exerts regional effects on ribosomal structure. A resistance gene (
aph) which encodes a spectinomycin has been cloned from
Legionella pneumophila (disease agent for Legionnaire’s disease) kinase and expressed in
E. coli.
Potency: ≥500 μg/mg.
Spectinomycin dihydrochloride pentahydrate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Spectinomycin dihydrochloride pentahydrate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 291)Lieferanten
22189-32-8()Verwandte Suche:
- SPECTINOMYCIN 2HCL
- SPECTINOMYCIN DIHYDROCHLORIDE PENTAHYDRATE
- SPECTINOMYCIN, DIHYDROCHLORIDE, PENTAHYDRATE, STREPTOMYCES SPECIES
- U-18409AE
- M 141
- ACTINOSPECTACIN DIHYDROCHLORIDE PENTAHYDRATE
- ACTINOSPECTACIN DIHYDROCHLORIDE
- espectinomicinadihydrochloridepentahydrate
- m141dihydrochloridepentahydrate
- SPECTINOMYCIN.2HCLRESEARCH GRADE
- Spectinomycin Hydrochloride (200 mg)G0C310650ug/mg(ai)
- Spectinomycin Hydrochloride (200 mg)
- 2alpha,4abeta,5abeta,6beta,7beta,8beta,9alpha,9aalpha,10abeta)]-Decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis-(methylamino)-4H-pyrano[2,3-b][1,4]benzodioxin-4-one dihydrochloride pentahydrate
- Togamycin dihydrochloride pentahydrate
- D00869
- Spectinomycin hydrochloride (jp15/usp)
- Spectinomycin hydrochloride hydrate
- Trobicin (tn)
- SpectinoMycin-2HCl pentahydrate research grade
- Spectinomycin Hcl Sterile EP 5
- Spectinomycin dihydrochloride pentahydrate, 650 IU/mg
- SPECTINOMYCIN DIHYDROCHLORIDE PENTAH
- SPECTINOMYCIN DIHYDROCHLORIDE PENTAHYDRATE from Streptomyces sp.
- spectogard
- Spectinomycin HCL USP/BP
- SPECTINOMYCIN DIHYDROCHLORIDE CELL*CULTU RE TESTED
- SPECTINOMYCIN DIHYDROCHLORIDE PENT
- SPECTINOMYCIN DIHYDROCHLORIDE GAMMA-*IRR ADIATED MOL
- SPECTINOMYCIN DIHYDROCHLORIDE HYDRATE, B
- 4H-Pyrano2,3-b1,4benzodioxin-4-one, decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-, dihydrochloride, pentahydrate, (2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-
- SOECTINOMYCINHYDROCHLORIDEPENTAHYDRATE
- Dihydrochloride pentahydrate
- Spectinomycin hcl /Spectinomycin hydrochloride
- Spectinomycin dihydrochloride pentahydrate, potency: ≥603 μg/mg
- 4H-Pyrano[2,3-b][1,4]benzodioxin-4-one,decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-, hydrochloride,hydrate (1:2:5), (2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-
- Spectinomycin dihydrochloride pentahydrate, >=779 u/mg
- Spectinomycin for system suitability CRS
- Spectinomycin hydrochloride CRS
- Spectinomycin,≥98%
- Spectinomycin dihydrochL
- (2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-4a,7,9-Trihydroxy-2-methyl-6,8-bis(methylamino)decahydro-4H-benzo[b]pyrano[2,3-e][1,4]dioxin-4-one dihydrochloride pentahydrate
- Spectinomycin Dihydrochloride Pentahydrate Sterile
- Spectinomycin dihydrochloride pentahydrate USP/EP/BP
- Spectinomycin dihydrochloride 5-hydrate
- Spectinomycin Hydrochloride (1618003)
- SPECTINOMYCIN PENTAHYDRATE DIHYDROCHLORIDE
- SPECTINOMYCIN HCL
- SPECTINOMYCIN HYDROCHLORIDE
- Spectinomycin 2HCl 5H2O
- Spectinomycin dihydrochloride pentahydrate in methanol
- C16972700 Spectinomycin dihydrochloridEpenta
- 22189-32-8
- C14H24N2O72HCl5H2O
- C14H24N2O72ClH5H2O
- C14H36Cl2N2O12
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