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Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate

Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate Struktur
112889-02-8
CAS-Nr.
112889-02-8
Englisch Name:
Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate
Synonyma:
Raltitrexed Impurity 24;diethyl n-[5-methylamino-2-thenoyl]-l-glutamate;Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate USP/EP/BP;(S)-Diethyl 2-(5-(MethylaMino)thiophene-2-carboxaMido)pentanedioate;n-[[5-(methylamino)-2-thienyl]carbonyl]-l-glutamic acid diethyl ester;iethyl(2S)-2-[[5-(methylamino)thiophene-2-carbonyl]amino]pentanedioate;L-Glutamic acid, N-[[5-(methylamino)-2-thienyl]carbonyl]-, 1,5-diethyl ester
CBNumber:
CB0855299
Summenformel:
C15H22N2O5S
Molgewicht:
342.41
MOL-Datei:
112889-02-8.mol

Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate Eigenschaften

Siedepunkt:
519.6±50.0 °C(Predicted)
Dichte
1.231
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
12.89±0.46(Predicted)

Sicherheit

Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

N-[[5-(Methylamino)-2-thienyl]carbonyl]-L-glutamic Acid Diethyl Ester can be used as reactant/reagent for synthetic preparation of Raltitrexed (anticancer agent). An intermediate or impurity in the synthesis of Raltitrexed (R100500). Raltitrexed (R100500) is folate-based inhibitor of thymidylate synthase; rapidly and extensively metabolized to its more potent polyglutamate derivatives. Antineoplastic.

Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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112889-02-8()Verwandte Suche:


  • n-[[5-(methylamino)-2-thienyl]carbonyl]-l-glutamic acid diethyl ester
  • diethyl n-[5-methylamino-2-thenoyl]-l-glutamate
  • (S)-Diethyl 2-(5-(MethylaMino)thiophene-2-carboxaMido)pentanedioate
  • L-Glutamic acid, N-[[5-(methylamino)-2-thienyl]carbonyl]-, 1,5-diethyl ester
  • iethyl(2S)-2-[[5-(methylamino)thiophene-2-carbonyl]amino]pentanedioate
  • Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate USP/EP/BP
  • Raltitrexed Impurity 24
  • 112889-02-8
  • Raltitrexed
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