Lofexidine hydrochloride
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- CAS-Nr.
- 21498-08-8
- Englisch Name:
- Lofexidine hydrochloride
- Synonyma:
- BA-168;loxacor;Baq 168;BRITLOFEX;MDL-14042A;lofetensin;LOFEXIDINE HCL;LOFETENSIN,LOXACOR;loxacorhydrochloride;lofetensinhydrochloride
- CBNumber:
- CB0731948
- Summenformel:
- C11H13Cl3N2O
- Molgewicht:
- 295.59
- MOL-Datei:
- 21498-08-8.mol
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Lofexidine hydrochloride Eigenschaften
- Schmelzpunkt:
- 230-232°C
- storage temp.
- -20°C Freezer
- L?slichkeit
- H2O: soluble20mg/mL, clear
- Aggregatzustand
- powder
- Farbe
- white to beige
- InChI
- InChI=1S/C11H12Cl2N2O.ClH/c1-7(11-14-5-6-15-11)16-10-8(12)3-2-4-9(10)13;/h2-4,7H,5-6H2,1H3,(H,14,15);1H
- InChIKey
- DWWHMKBNNNZGHF-UHFFFAOYSA-N
- SMILES
- C1(=C(Cl)C=CC=C1Cl)OC(C)C1=NCCN1.Cl
- CAS Datenbank
- 21498-08-8(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
T |
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| R-S?tze: |
25 |
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| S-S?tze: |
45 |
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| RIDADR |
UN 2811 6.1 / PGIII |
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| WGK Germany |
3 |
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| HazardClass |
6.1 |
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| Toxizit?t |
LD50 in mice, rats, dogs (mg/kg): between 74-147 orally (all species); between 8-18 i.v. (all species) (Tsai) |
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| Bildanzeige (GHS) |
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H301 |
Giftig bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 3 |
Achtung |
![GHS hazard pictograms]() src="/GHS06.jpg" width="20" height="20" /> |
P264, P270, P301+P310, P321, P330,P405, P501 |
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| Sicherheit |
| P301+P310 |
BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
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Lofexidine hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
Crystalline Solid
Verwenden
Lofexidine hydrochloride is an α2-adrenergic receptor agonist (Kd = 7.6 nM for rat cerebral cortex membranes) that has transient antihypertensive effects. It is used in managing opioid withdrawal symptoms during detoxification from heroin and methadone.
Lofexidine hydrochloride Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Lofexidine hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 135)Lieferanten
21498-08-8()Verwandte Suche:
- 2-[1-(2,6-dichlorophenoxy)ethyl]-2-imidazoline hydrochloride
- 2-[1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-1h-imidazole hydrochloride
- 2-(1-(2,6-dichlorophenoxy)ethyl)-2-imidazolinmonohydrochloride
- LOFETENSIN,LOXACOR
- LOFEXIDINE HCL
- LOFEXIDINE, HYDROCHLORIDE
- MDL-14042A
- BA-168
- BRITLOFEX
- 2-(1-(2,6-dichlorophenoxy)ethyl)-4,5-dihydro-1h-imidazolmonohydrochlorid
- 2-(1-(2,6-dichlorphenoxy)aethyl)-2-imidazolin-hydrochlorid
- lofetensin
- lofetensinhydrochloride
- loxacor
- loxacorhydrochloride
- MDL-14042A, Ba-168, Britlofex, Lofetensin,Loxacor
- 1H-IMidazole,2-[1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-, hydrochloride (1:1)
- Baq 168
- Lofexidine hydrochloride###Lofexidine
- 2-[1-(2,6-Dichlorophenoxy)ethyl]-4,5-dihydro-
- Lofexidine hydrochloride USP/EP/BP
- 21498-08-8
- C11H13Cl3N2O
- C11H12Cl2N2OHCl
- C11H12Cl2N2OClH
- Aromatics
- Heterocycles
- Active Pharmaceutical Ingredients
- BRITLOFEX
- Intermediates & Fine Chemicals
- Pharmaceuticals
