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GNE-781

GNE-781 Struktur
1936422-33-1
CAS-Nr.
1936422-33-1
Englisch Name:
GNE-781
Synonyma:
GNE-781;GNE-781,Histone Acetyltransferase,Inhibitor,HATs,Epigenetic Reader Domain,GNE 781,HAT,inhibit,GNE781;3- (7-(difluoromethyl)-6-(1-methylpyrazol-4-yl)-3.4-dihydro-2H-quinohn-1-yl]-N-methyl-1-(oxan-4-yl)-6,7-dihydro-4H-pyrazolo[4.3-c]pyridine-5-carboxamide;3-(7-(difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)-N-methyl-1-(tetrahydro-2H-pyran-4-yl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxamide;5H-Pyrazolo[4,3-c]pyridine-5-carboxamide, 3-[7-(difluoromethyl)-3,4-dihydro-6-(1-methyl-1H-pyrazol-4-yl)-1(2H)-quinolinyl]-1,4,6,7-tetrahydro-N-methyl-1-(tetrahydro-2H-pyran-4-yl)-
CBNumber:
CB04667955
Summenformel:
C27H33F2N7O2
Molgewicht:
525.59
MOL-Datei:
1936422-33-1.mol

GNE-781 Eigenschaften

Schmelzpunkt:
135-140oC
Siedepunkt:
800.7±65.0 °C(Predicted)
Dichte
1.45±0.1 g/cm3(Predicted)
storage temp. 
Refrigerator
L?slichkeit
DMSO (Slightly), Methanol (Slightly)
pka
14.19±0.20(Predicted)
Aggregatzustand
Solid
Farbe
White to Pale Yellow

Sicherheit

GNE-781 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

GNE-781 is a highly advanced, potent and selective bromodomain inhibitor of cyclic adenosine monophosphate response element binding protein, binding protein (CBP). Inhibition of the bromodomain of the transcriptional regulator CBP/P300 is an especially interesting new therapeutic approach in oncology.

GNE-781 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


GNE-781 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 38)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32951 60
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 49374 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32072 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226
sales@hzclap.com CHINA 6312 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471
sales@sarms4muscle.com China 10473 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207
sales@molcore.com China 49734 58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd
+86-18341751992 +86-15382112998
757984502@qq.com China 892 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 57505 58
Shanghai SuperLan Chemcial Technique Centre 021-2022843681 15618226720
lucy@atkchemical.com China 8752 58
Wuhan Acumen Bio-Technology Co.,ltd 027-027-16602739303 16602739303
673003916@qq.com China 3059 58

  • GNE-781
  • 5H-Pyrazolo[4,3-c]pyridine-5-carboxamide, 3-[7-(difluoromethyl)-3,4-dihydro-6-(1-methyl-1H-pyrazol-4-yl)-1(2H)-quinolinyl]-1,4,6,7-tetrahydro-N-methyl-1-(tetrahydro-2H-pyran-4-yl)-
  • 3-(7-(difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)-N-methyl-1-(tetrahydro-2H-pyran-4-yl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxamide
  • 3- (7-(difluoromethyl)-6-(1-methylpyrazol-4-yl)-3.4-dihydro-2H-quinohn-1-yl]-N-methyl-1-(oxan-4-yl)-6,7-dihydro-4H-pyrazolo[4.3-c]pyridine-5-carboxamide
  • GNE-781,Histone Acetyltransferase,Inhibitor,HATs,Epigenetic Reader Domain,GNE 781,HAT,inhibit,GNE781
  • 1936422-33-1
  • 1396422-33-1
  • C27H33F2N7O2
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