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Phenelzin

Phenelzine Struktur
51-71-8
CAS-Nr.
51-71-8
Bezeichnung:
Phenelzin
Englisch Name:
Phenelzine
Synonyma:
nadil;Nardil;W-1544;w1544-a;W 1544-A;Fenelzyne;Fenelzyna;Stinerval;Phenalzine;PHENELZINE
CBNumber:
CB0434063
Summenformel:
C8H12N2
Molgewicht:
136.19
MOL-Datei:
51-71-8.mol

Phenelzin Eigenschaften

Schmelzpunkt:
25°C
Siedepunkt:
bp0.1 74°
Dichte
1.0348 (rough estimate)
Brechungsindex
nD20 1.5494
pka
8.01±0.70(Predicted)
CAS Datenbank
51-71-8(CAS DataBase Reference)
NIST chemische Informationen
Hydrazine, (2-phenylethyl)-(51-71-8)
EPA chemische Informationen
Phenelzine (51-71-8)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xi
HazardClass  IRRITANT
Giftige Stoffe Daten 51-71-8(Hazardous Substances Data)
Toxizit?t LD50 oral in mouse: 130mg/kg
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H341 Kann vermutlich genetische Defekte verursachen. Keimzellmutagenit?t Kategorie 2 Warnung P201,P202, P281, P308+P313, P405,P501
Sicherheit
P201 Vor Gebrauch besondere Anweisungen einholen.
P202 Vor Gebrauch alle Sicherheitshinweise lesen und verstehen.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P308+P313 BEI Exposition oder falls betroffen: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen.
P405 Unter Verschluss aufbewahren.
P501 Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

Phenelzin Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Monoamine oxidase inhibitors (MAOIs) were the first antidepressant drugs introduced during the 1950s. Associated with many side effects and, in particular, drug–drug and drug–food interactions, their use declined with the subsequent introduction of the tricyclic antidepressants and specific serotonin reuptake inhibitors as first-line treatments for depression.

Verwenden

Phenelzine is a MAO inhibitor which is used for treating patients with depressive characteristics such as “atypical,” “nonendogenous,” or “neurotic” conditions in which a combination of anxiety, depression, or phobia are observed. Phenelzine is not a drug of first choice, and it is used in depressions that do not respond to other medicinal drugs.

Mechanism of action

Phenelzine is a hydrazine MAOI. Its mechanism of action is the prolonged, nonselective, irreversible inhibition of MAO. Phenelzine has been used with some success in the management of bulimia nervosa. The MAOIs, however, are potentially dangerous in patients with binge eating and purging behaviors, and the American Psychiatric Association states that MAOIs should be used with caution in the management of bulimia nervosa.

Sicherheitsprofil

Poison by ingestion, intraperitoneal, and subcutaneous routes. Human systemic effects by ingestion: ataxia, somnolence. An experimental teratogen. Experimental reproductive effects. Mutation data reported. Used as an antidepressant. When heated to decomposition it emits toxic fumes of NOx.

Environmental Fate

MAOIs are available orally. Accidental or intentional ingestion are the most common routes of exposure.

Phenelzin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Phenelzin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 69)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806
sales@capot.com China 29791 60
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21634 55
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 49374 58
Hubei Ipure Biology Co., Ltd
+8613367258412
ada@ipurechemical.com China 10319 58
Career Henan Chemica Co
+86-0371-86658258 +8613203830695
laboratory@coreychem.com China 30239 58
Shaanxi Didu New Materials Co. Ltd
+86-89586680 +86-13289823923
1026@dideu.com China 8670 58
TargetMol Chemicals Inc.

support@targetmol.com United States 38631 58
LEAPCHEM CO., LTD.
+86-852-30606658
market18@leapchem.com China 43340 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+undefined18621343501
product@acmec-e.com China 33338 58
Jilin Chinese Academy of Sciences-yanshen Technology
+undefined18143011203
info@chemextension.com China 42056 58

51-71-8(Phenelzin)Verwandte Suche:


  • (2-phenylethyl)-hydrazin
  • 1-(2-Phenylethyl)hydrazine
  • 1-hydrazino-2-phenylethane
  • 2-Phenethylhydrazine
  • Fenelzyna
  • Fenelzyne
  • Hydrazine, (2-phenylethyl)-
  • Hydrazine, phenethyl-
  • nadil
  • Nardil
  • Phenalzine
  • 2-PHENELZINE
  • (2-PHENYL-ETHYL)-HYDRAZINE
  • PHENETHYL HYDRAZINE
  • PHENELZINE
  • ASINEX-REAG BAS 07650440
  • BETA-PHENYLETHYLHYDRAZINE
  • phenethyl-hydrazin
  • Phenylethylhydrazine
  • Stinerval
  • W 1544-A
  • W-1544
  • w1544-a
  • Phenelzine USP/EP/BP
  • Phenelezine
  • 51-71-8
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