80454-42-8
80454-42-8 結(jié)構(gòu)式
基本信息
中文別名
芍藥苷元酮芍藥甙元酮
英文別名
paeoniflorigenone2,5-Methano-1,3-benzodioxol-6(3aH)-one, 8-[(benzoyloxy)methyl]tetrahydro-3a-hydroxy-7a-methyl-, (2S,3aR,5R,7aS,8S)-
所屬類別
天然產(chǎn)物：萜類物理化學(xué)性質(zhì)
沸點(diǎn)481.1±45.0 °C(Predicted)
密度1.396±0.06 g/cm3(Predicted)
儲(chǔ)存條件4°C, protect from light
溶解度Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
酸度系數(shù)(pKa)11.81±0.60(Predicted)
形態(tài)粉末
顏色White to off-white
芍藥甙元酮價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2024/11/08 | HY-N3119 | 芍藥甙元酮 Paeoniflorigenone | 80454-42-8 | 1mg | 8000元 |
常見問題列表
生物活性
Paeoniflorigenone 是從牡丹皮中提取的一種有效成分，具有選擇性誘導(dǎo)腫瘤細(xì)胞凋亡 (apoptosis) 和抗增殖作用。體外研究
Paeoniflorigenone (0-30 μM; 0-72 hours) significantly decreases the cell proliferation of tumor cell lines and inhibits the proliferation of normal cell lines.
Paeoniflorigenone (0-30 μM; 24-72 hours) significantly induces apoptotic DNA fragmentation selectively in tumor cells.
Cell Proliferation Assay
| Cell Line: | TIG-1, 3T3-L1, HL60, Jurkat and HeLa cells |
| Concentration: | 0-30 μM |
| Incubation Time: | 0-72 hours |
| Result: | Significantly decreased the cell proliferation of tumor cell lines and inhibited the proliferation of normal cell lines. |
Apoptosis Analysis
| Cell Line: | TIG-1 and 3T3-L1 (normal cells), HL60, Jurkat, and HeLa cells (tumor cells) |
| Concentration: | 0, 1, 3, 10, 30 μM |
| Incubation Time: | 24 and 72 hours |
| Result: | Induced DNA fragmentation in three tumor cell lines, but not in two normal cell lines. |