7179-49-9
中文名稱
鹽酸林可霉素(一水物)
英文名稱
Lincomycin hydrochloride monohydrate
CAS
7179-49-9
EINECS 編號(hào)
212-726-7
分子式
C18H37ClN2O7S
MDL 編號(hào)
MFCD00167245
分子量
461.01
MOL 文件
7179-49-9.mol
更新日期
2024/11/07 11:02:35
7179-49-9 結(jié)構(gòu)式
基本信息
中文別名
鹽酸林可霉素6-(1-甲-反-丙基-L-2-吡咯烷甲酰氨基)-1-硫代-6,8-二脫氧-D-赤式-A-D-半乳辛吡喃糖苷鹽酸
潔霉素鹽酸鹽
林可霉素
鹽酸潔霉素
林可霉素鹽酸鹽
6,8-二脫氧-6-(1-甲基-4-丙基-L-2-吡咯烷甲酰氨基)-1-硫代-D-赤式-alpha-D-半乳辛吡喃糖苷鹽酸鹽(一水物)
鹽酸林可霉素(一水物)
英文別名
LINCOCIN HYDROCHLORIDE MONOHYDRATElincomycin hydrochloride bp98
LINCOMYCIN HYDROCHLORIDE MONOHYDRATE
lincorex
methyl (2s-trans)-6,8-dideoxy-6-[[(1-methyl-4-propylpyrrolidin-2-yl)carbonyl]amino]-1-thio-d-erythro-alpha-d-galacto-octopyranoside monohydrochloride
d-erythro-d-galacto-octopyranoside,methyl6,8-dideoxy-6-(1-methyl-4-propyl-2-pyrrolidinecarboxamido)-1-thio-,monohydrochloride,hemihydrate
frademicina
lincocinhydrochloridehydrate
lincomycin,hydrochloride,hemihydrate
lincomycin,hydrochloridehydrate
methyl6,8-dideoxy-6-(1-methyl-4-propyl-2-d-erythro-d-galacto-octopyranosid
mycivin
pyrrolidinecarboxamido)-1-thio-,monohydrochloride,hemihydrate
waynecomycin
LINCOMYCIN HYDROCHLORIDE, HYDRATE, VETRA
LINCOMYCINHYDROCHLORIDE,MONOHYDRATE,USP
Lincocin
Lincomycin hydrochloride BP98
Lincomycin hydrochloride monohydrate
Lincorex
所屬類別
原料藥：林可胺類藥物理化學(xué)性質(zhì)
外觀性狀白色結(jié)晶性粉未，微臭，味苦。該藥抗菌譜廣，無(wú)過(guò)敏性，穿透力強(qiáng)，是髓炎等骨科病的首選抗菌藥物。
熔點(diǎn)156-158°
比旋光度D25 +143° (water)
儲(chǔ)存條件2-8°C
溶解度Very soluble in water, slightly soluble in ethanol (96 per cent), very slightly soluble in acetone.
形態(tài)neat
顏色White to Almost white
Merck5500
InChIKeyLFZGYTBWUHCAKF-DCNJEFSFSA-N
CAS 數(shù)據(jù)庫(kù)7179-49-9(CAS DataBase Reference)
安全數(shù)據(jù)
警示詞警告
危險(xiǎn)性描述H315-H319-H335
危險(xiǎn)品標(biāo)志Xi
危險(xiǎn)類別碼36/37/38
安全說(shuō)明26
WGK Germany2
RTECS號(hào)RH6315500
海關(guān)編碼29419090
應(yīng)用領(lǐng)域
用途一
與紅霉素相似，對(duì)革蘭陽(yáng)性菌有強(qiáng)大的抗菌作用用途二
與紅霉素相似，對(duì)革蘭氏陽(yáng)性菌有強(qiáng)大的抗菌作用。鹽酸林可霉素(一水物)價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2024/08/19 | L0166 | 鹽酸林可霉素一水合物 Lincomycin Hydrochloride Monohydrate | 7179-49-9 | 5G | 720元 |
| 2024/08/19 | L0166 | 鹽酸林可霉素一水合物 Lincomycin Hydrochloride Monohydrate | 7179-49-9 | 25G | 1390元 |
| 2024/08/19 | S5295 | 鹽酸林可霉素(一水物) Lincomycin Hydrochloride Monohydrate | 7179-49-9 | 25mg | 794.47元 |
常見(jiàn)問(wèn)題列表
生物活性
Lincomycin hydrochloride monohydrate 是窄譜抗生素, 具有與紅霉素相似的效力, 對(duì)革蘭氏陽(yáng)性球菌具有很好的作用效果, 主要抑制細(xì)菌細(xì)胞蛋白質(zhì)的合成。體內(nèi)研究
Lincomycin (25 and 50 mg/kg, intravenously) depresses neuromuscular transmission to a degree which depended on stimulation frequencies in the rabbit sciatic nerve-gastrocnemius muscle preparation.
| Animal Model: | Adult albino New Zealand rabbits weighing 2.5-3.5 kg. |
| Dosage: | 25 and 50 mg/kg. |
| Administration: | Intravenously. |
| Result: | Depressed neuromuscular transmission. |