644-78-0
中文名稱
2-羥基查酮
英文名稱
2-HYDROXYCHALCONE
CAS
644-78-0
EINECS 編號
211-422-1
分子式
C15H12O2
MDL 編號
MFCD00016449
分子量
224.25
MOL 文件
644-78-0.mol
更新日期
2023/03/20 19:41:19
644-78-0 結(jié)構(gòu)式
基本信息
中文別名
2-羥基查酮2-羥基查耳酮,98+%
英文別名
2-(2-HYDROXYBENZAL)ACETOPHENONE2-(2-HYDROXYBENZYLIDENE)ACETOPHENONE
2-HYDROXYBENZYLIDENE ACETOPHENONE
2-HYDROXYCHALCONE
BENZYLIDENE-2-HYDROXYACETOPHENONE
(E)-3-(2-HYDROXYPHENYL)-1-PHENYLPROP-2-EN-1-ONE
HYDROXYCHALCONE, 2-
SALICYLALACETOPHENONE
TRANS-2-HYDROXYBENZYLIDENEACETOPHENONE
TRANS-2-HYDROXYCHALCONE
(2-Hydroxybenzylidene)acetophenone~3-(2-Hydroxyphenyl)-1-phenyl-2-propen-1-one
2-Hydroxychalcone, 98+%
3-(2-hydroxyphenyl)-1-phenyl-2-propen-1-one
2-HYDROXYCHALCONE(UNSPECIFIEDISOMER)
3-(2-hydroxyphenyl)-1-phenylprop-2-en-1-one
o-Hydroxychalcone
α-(o-Hydroxybenzylidene)acetophenone
所屬類別
生物化工：提取物物理化學(xué)性質(zhì)
熔點144-150 °C(lit.)
沸點396.3±34.0 °C(Predicted)
密度1.191±0.06 g/cm3(Predicted)
酸度系數(shù)(pKa)9.26±0.35(Predicted)
形態(tài)粉末
顏色黃色
BRN2049134
CAS 數(shù)據(jù)庫644-78-0(CAS DataBase Reference)
常見問題列表
生物活性
2-hydroxychalcone 是一種天然黃酮，是一種抗氧化劑，抑制脂質(zhì)過氧化。2-hydroxychalcone 通過下調(diào) Bcl-2 誘導(dǎo)凋亡。2-Hydroxychalcone 可抑制NF-kB 的激活。體外研究
2-Hydroxychalcone inhibits invasion of triple negative breast cancer cells.
2-hydroxychalcone inhibits the adhesion of peripheral neutrophils to the endothelial cell monolayers by inhibiting the expression of ICAM-1, VCAM-1, and E-selectin in a concentration-dependent manner.